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Chronic Obstructive Airway Disease (CUI C0024117) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0024117

NCI Thesaurus Code: C3199  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema.

RADLEX Definition: A disease of chronic diffuse irreversible airflow obstruction. Subcategories of copd include chronic bronchitis and pulmonary emphysema. [MeSH]

MEDLINEPLUS Definition: 

COPD (chronic obstructive pulmonary disease) makes it hard for you to breathe. The two main types are chronic bronchitis and emphysema. The main cause of COPD is long-term exposure to substances that irritate and damage the lungs. This is usually cigarette smoke. Air pollution, chemical fumes, or dust can also cause it.

At first, COPD may cause no symptoms or only mild symptoms. As the disease gets worse, symptoms usually become more severe. They include

  • A cough that produces a lot of mucus
  • Shortness of breath, especially with physical activity
  • Wheezing
  • Chest tightness

Doctors use lung function tests, imaging tests, and blood tests to diagnose COPD. There is no cure. Treatments may relieve symptoms. They include medicines, oxygen therapy, surgery, or a lung transplant. Quitting smoking is the most important step you can take to treat COPD.

NIH: National Heart, Lung, and Blood Institute

NCI-GLOSS Definition: A type of lung disease marked by permanent damage to tissues in the lungs, making it hard to breathe. Chronic obstructive pulmonary disease includes chronic bronchitis, in which the bronchi (large air passages) are inflamed and scarred, and emphysema, in which the alveoli (tiny air sacs) are damaged. It develops over many years and is usually caused by cigarette smoking.

CSP Definition: chronic, irreversible obstruction of air flow from the lungs.

MSH Definition: A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.

Synonyms & Abbreviations: (see Synonym Details)
-- COPD
CAFL - Chronic airflow limitation
CAL - Chronic airflow limitation
Chronic airflow limitation
Chronic airway disease
Chronic airway obstruction
Chronic irreversible airway obstruction
Chronic obstruct airways disease
Chronic obstructive airway disease NOS
Chronic Obstructive Airway Disease
CHRONIC OBSTRUCTIVE AIRWAY DIS
Chronic obstructive airways disease
Chronic obstructive lung disease (disorder)
Chronic obstructive lung disease NOS
chronic obstructive lung disease
CHRONIC OBSTRUCTIVE LUNG DIS
CHRONIC OBSTRUCTIVE PULM DIS
Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease NOS
Chronic Obstructive Pulmonary Disease, (COPD)
Chronic obstructive pulmonary disease, unspecified
chronic obstructive pulmonary disease
Chronisch obstruktive Lungenerkrankung
COAD - Chronic obstructive airways disease
COAD
COLD (chronic obstructive lung disease)
COLD - Chronic obstructive lung disease
COLD
COPD - Chronic obstructive pulmonary disease
COPD NOS
COPD, Chronic Obstructive Pulmonary Disease
COPD
Disease (COPD), Chronic Obstructive
HYPERACTIVE AIRWAY DISEASE
Obstructive airways disease (chronic)
Obstructive Pulmonary Disease (COPD), Chronic
PULM DIS CHRONIC OBSTRUCTIVE
Pulmonary Disease (COPD), Chronic Obstructive
Pulmonary Disease, Chronic Obstructive [Disease/Finding]
Pulmonary Disease, Chronic Obstructive
small airways disease

External Source Codes: 
NCI Thesaurus Code C3199 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN LUNG DISEASES, OBSTRUCTIVE is also available MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source CTRP NCI
Contributing_Source FDA NCI
CTV3ID XU7bI SNOMEDCT_US
DATE_CREATED 10/22/1998 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 4004-0004 CSP
DX 20020101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
FDA_Table Patient Code (Appendix B) NCI
GENELOCUS ,2,2,q,1,2, OMIM
GENESYMBOL HMOX1D OMIM
GENESYMBOL HMOX1 OMIM
HN 2002; use LUNG DISEASES, OBSTRUCTIVE 1984-2001 MSH
IAN DEFAULT ICD10
INCLUSION_TERM Chronic obstructive: airway disease NOS ICD10
INCLUSION_TERM Chronic obstructive: lung disease NOS ICD10
MDA 20010725 MSH
MESH_DEFINITION A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA. NDFRT
MESH_DUI D029424 NDFRT
MESH_NAME Pulmonary Disease, Chronic Obstructive NDFRT
MESH_UI M0384655 NDFRT
MIMTYPE 5 OMIM
MIMTYPEMEANING Mendelian phenotype or locus, molecular basis unknown. OMIM
MIMTYPEVALUE perc OMIM
MMR 20120703 MSH
MN C08.381.495.389 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MODULE_ID 731000124108 SNOMEDCT_US
MODULE_NAME US National Library of Medicine maintained module SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/copd.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Arabic https://www.nlm.nih.gov/medlineplus/languages/copd.html#Arabic MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Bosnian https://www.nlm.nih.gov/medlineplus/languages/copd.html#Bosnian MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Simplified https://www.nlm.nih.gov/medlineplus/languages/copd.html#Chinese - Simplified MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Traditional https://www.nlm.nih.gov/medlineplus/languages/copd.html#Chinese - Traditional MEDLINEPLUS
MP_OTHER_LANGUAGE_URL French https://www.nlm.nih.gov/medlineplus/languages/copd.html#French MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Hindi https://www.nlm.nih.gov/medlineplus/languages/copd.html#Hindi MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Japanese https://www.nlm.nih.gov/medlineplus/languages/copd.html#Japanese MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Korean https://www.nlm.nih.gov/medlineplus/languages/copd.html#Korean MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Portuguese https://www.nlm.nih.gov/medlineplus/languages/copd.html#Portuguese MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Russian https://www.nlm.nih.gov/medlineplus/languages/copd.html#Russian MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Somali https://www.nlm.nih.gov/medlineplus/languages/copd.html#Somali MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/copd.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Tagalog https://www.nlm.nih.gov/medlineplus/languages/copd.html#Tagalog MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Vietnamese https://www.nlm.nih.gov/medlineplus/languages/copd.html#Vietnamese MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Heart, Lung, and Blood Institute http://www.nhlbi.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NUI N0000011155 NDFRT
ORDER_NO 12581 ICD10CM
PM 2002; see LUNG DISEASES, OBSTRUCTIVE 1984-2001 MSH
PRIMARY_PATH 10009033$10006484$10006436$10038738$Chronic obstructive pulmonary disease$Bronchospasm and obstruction$Bronchial disorders (excl neoplasms)$Respiratory, thoracic and mediastinal disorders MDR
PRIMARY_SOC 10038738 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3126632 RXNORM
RXAUI 3127589 RXNORM
RXAUI 3133440 RXNORM
RXAUI 3133441 RXNORM
RXAUI 3133442 RXNORM
RXAUI 3226023 RXNORM
RXAUI 3226024 RXNORM
RXCUI 1024395 RXNORM
SNOMED_CID 13645005 NDFRT
SNOMEDID D2-60000 SNOMEDCT_US
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS J44.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~J44.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS J44.9 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~J44.9 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU7bI SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~D2-60000 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T024359 MSH
TERMUI T024360 MSH
TERMUI T024361 MSH
TERMUI T024362 MSH
TERMUI T024364 MSH
TERMUI T024365 MSH
TH NLM (1998) MSH
TH OMIM (2013) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0024117

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