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Liver Cirrhosis, Alcoholic (CUI C0023891) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0023891

NCI Thesaurus Code: C34782  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A disorder of the liver characterized by the presence of fibrotic scar tissue instead of healthy liver tissue. This condition is attributed to excessive consumption of alcoholic beverages.

CSP Definition: liver disease in alcoholics in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

MSH Definition: FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING.

Synonyms & Abbreviations: (see Synonym Details)
Alcohol cirrhosis liver
Alcoholic cirrhosis (disorder)
Alcoholic cirrhosis NOS
Alcoholic cirrhosis of liver
alcoholic cirrhosis
Alcoholic Hepatic Cirrhosis
alcoholic liver cirrhosis
Cirrhosis alcoholic
CIRRHOSIS, ALCOHOLIC
Hepatic Cirrhosis, Alcoholic
Liver Cirrhosis, Alcoholic [Disease/Finding]
Liver Cirrhosis, Alcoholic

External Source Codes: 
NCI Thesaurus Code C34782 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL BL CF CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CTV3ID XUdBK SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 1754-7677 CSP
DX 19780101 MSH
EFFECTIVE_TIME 20060131 SNOMEDCT_US
HN 78 MSH
IAN DEFAULT ICD10
ICE Florid cirrhosis; Laennec's cirrhosis (alcoholic) ICD9CM
INCLUSION_TERM Alcoholic cirrhosis NOS ICD10
MDA 19770329 MSH
MESH_DEFINITION FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING. NDFRT
MESH_DUI D008104 NDFRT
MESH_NAME Liver Cirrhosis, Alcoholic NDFRT
MESH_UI M0012638 NDFRT
MMR 20130708 MSH
MN C06.552.630.380 MSH
MN C06.552.645.590 MSH
MN C25.775.100.087.645.550 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DISEASE_KIND NDFRT
NUI N0000001863 NDFRT
ORDER_NO 13534 ICD10CM
PM 78 MSH
PRIMARY_PATH 10009208$10019669$10019654$10019805$Cirrhosis alcoholic$Hepatic fibrosis and cirrhosis$Hepatic and hepatobiliary disorders$Hepatobiliary disorders MDR
PRIMARY_SOC 10019805 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3107452 RXNORM
RXAUI 3172140 RXNORM
RXAUI 3189942 RXNORM
RXAUI 3189943 RXNORM
RXCUI 1022062 RXNORM
SMQ_TERM_ADDVERSION 8.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 12.1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 420054005 NDFRT
SOS A severe form of alcoholic liver disease, characterized by necrosis and permanent architectural distortion of the liver due to fibrous tissue formation and regeneratory nodules. This is a strictly histological definition, but diagnosis is often made on clinical grounds only. Alcoholic liver cirrhosis occurs mainly in the 40-60 year age group, after at least 10 years of hazardous drinking. Individuals show symptoms and signs of hepatic decompensation such as ascites, ankle edema, jaundice, bruising, gastrointestinal hemorrhage from esophageal varices, and confusion or stupor due to hepatic encephalopathy. About 30 percent of patients are "well compensated" at the time of diagnosis and present with nonspecific complaints such as abdominal pain, bowel disturbance, weight loss, and muscle wasting and weakness. Liver cancer is a late complication of cirrhosis in approximately 15 percent of cases. AOD
SOS Alcoholic cirrhosis is sometimes termed portal cirrhosis or Laennec's cirrhosis, although these terms do not necessarily imply an alcoholic causation. In nontropical countries with substantial alcohol consumption, alcohol use is a dominant cause of cirrhosis. Due to under-recording of the alcohol connection, total cirrhosis mortality rather than "cirrhosis with mention of alcoholism" is often used as an alcohol problems indicator (see for example the Jellinek formula). AOD
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS K70.3 | POSSIBLE REQUIREMENT FOR CAUSATIVE AGENT CODE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~K70.3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS K70.30 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~K70.30 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUdBK SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T024188 MSH
TERMUI T024189 MSH
TERMUI T550624 MSH
TH NLM (1978) MSH
TH NLM (2005) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0023891

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