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Linoleic Acid (CUI C0023749) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0023749

NCI Thesaurus Code: C615  (see NCI Thesaurus info)

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

Semantic Type: Biologically Active Substance

NCIt Definition: A polyunsaturated essential fatty acid found mostly in plant oils. It is used in the biosynthesis of prostaglandins and cell membranes.

CRCH Definition: Polyunsaturated fatty acid with 18 carbons and 2 double bonds at the 6th and 9th carbons from the methyl end

MSH Definition: A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed)

Synonyms & Abbreviations: (see Synonym Details)
(Z,Z)-9,12-Octadecadienoic Acid
9,12 Octadecadienoic Acid
9,12-Linoleic Acid
9,12-Octadecadienoic Acid
Acid, 9,12-Octadecadienoic
Cis, cis-octadeca-9,12-dienoic acid
Fatty Acid 18:2 n-6
Linoleic acid (substance)
Linoleic Acid [Chemical/Ingredient]
linoleic acid
Linolic Acid
OCTADECADIENOIC ACID 009 012

External Source Codes: 
NCI Thesaurus Code C615 (see NCI Thesaurus info)
CAS Registry Number 60-33-3 (see NLM ChemIDplus info)
CAS Registry Number 2197-37-7 (see NLM ChemIDplus info)
FDA UNII Code 9KJL21T0QJ
NSC Code 281243 (see NCI DTP info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN LINOLEIC ACIDS and LINOLEIC ACIDS, CONJUGATED are also available MSH
AQL AD AE AG AI AN BI BL CF CH CL CS CT DF EC GE HI IM IP ME PD PH PK PO RE SD SE ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHEBI_ID CHEBI:17351 NCI
Chemical_Formula CH3(CH2)4(CH=cisCHCH2)2(CH2)6COOH NCI
Contributing_Source CRCH NCI
Contributing_Source CTRP NCI
Contributing_Source FDA NCI
CTV3ID X80O5 SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DX 19980101 MSH
EC analogs & derivatives:Linoleic Acids MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
Essential_Fatty_Acid Y NCI
FDA_UNII_CODE 9KJL21T0QJ NDFRT
HN 98; use LINOLEIC ACID (NM) 1981-97 MSH
INFOODS F18D2CN6 NCI
LEVEL Ingredient NDFRT
Macronutrient Y NCI
MDA 19970620 MSH
MESH_DEFINITION A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed) NDFRT
MESH_DUI D019787 NDFRT
MESH_NAME Linoleic Acid NDFRT
MESH_UI M0029355 NDFRT
MMR 20160701 MSH
MN D10.251.355.310.515.500 MSH
MN D10.251.355.343.500.500 MSH
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006866 NDFRT
NUI N0000148142 NDFRT
Nutrient Y NCI
PM 98; LINOLEIC ACID was indexed under LINOLEIC ACIDS 1981-97 & FATTY ACIDS, UNSATURATED 1981-83 MSH
RN 9KJL21T0QJ MSH
RR 19704-83-7 (Ca salt(Z,Z)-isomer) MSH
RR 2197-37-7 (Linoleic Acid) MSH
RR 2420-42-0 ((Z,E)-isomer) MSH
RR 2420-55-5 ((E,Z)-isomer) MSH
RR 3131-66-6 (14C-labeled cpd(Z,Z)-isomer) MSH
RR 3414-89-9 (K salt(Z,Z)-isomer) MSH
RR 506-21-8 ((E,E)-isomer) MSH
RR 57431-47-7 (Na salt(E,E)-isomer) MSH
RR 60-33-3 ((Z,Z)-isomer) MSH
RR 7721-14-4 (NH4 salt(Z,Z)-isomer) MSH
RR 822-17-3 (Na salt(Z,Z)-isomer) MSH
RXAUI 207018 RXNORM
RXAUI 2072069 RXNORM
RXAUI 3094670 RXNORM
RXAUI 3187084 RXNORM
RXAUI 3187085 RXNORM
RXAUI 3189638 RXNORM
RXAUI 3189641 RXNORM
RXAUI 4234153 RXNORM
RXAUI 4234265 RXNORM
RXAUI 4238757 RXNORM
RXCUI 6400 RXNORM
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SUBSET_MEMBER 900000000000497000~MAPTARGET~X80O5 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T058833 MSH
TERMUI T058834 MSH
TH FDA SRS (2014) MSH
TH NLM (1998) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
Unit g NCI
US_Recommended_Intake Y NCI
USDA_ID 675 NCI
VANDF_RECORD 50.416^2877^Active/Master NDFRT
VANDF_RECORD 50.6^4091^Active/Master NDFRT
VUID 4020238 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0023749

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