skip navigation links
National Cancer Institute
Enterprise Vocabulary Services
Box
NCIm Version: 201706 Version 2.8 (using LexEVS 6.5)
SearchBox Top
SearchBox Bottom
Hairy Cell Leukemia (CUI C0023443) Suggest changes to this concept
Add to Cart

Terms & Properties Synonym Details Relationships Sources View All  
Terms & Properties

Concept Unique Identifier (CUI): C0023443

NCI Thesaurus Code: C7402  (see NCI Thesaurus info)

Semantic Type: Neoplastic Process

NCIt Definition: A neoplasm of small B-lymphocytes with "hairy" projections in bone marrow, spleen, and peripheral blood. Most patients present with splenomegaly and pancytopenia. (WHO, 2001)

GARD Definition: Hairy cell leukemia is a rare, slow-growing cancer of the blood in which the bone marrow makes too many B cells (lymphocytes), a type of white blood cell that fights infection. The condition is named after these excess B cells which look 'hairy' under a microscope. As the number of leukemia cells increases, fewer healthy white blood cells, red blood cells and platelets are produced. The underlying cause of this condition is unknown. While there is no cure, treatment can lead to remission which can last for years.    - this information is from GARD/ORDR/NCATS.

PDQ Definition: A rare neoplasm of small B-lymphocytes with "hairy" projections in bone marrow, spleen, and peripheral blood. Most patients are middle-aged to elderly adults and present with splenomegaly and pancytopenia. (WHO, 2001) Check for active clinical trials using this agent. (NCI Thesaurus)

NCI-GLOSS Definition: A rare type of leukemia in which abnormal B-lymphocytes (a type of white blood cell) are present in the bone marrow, spleen, and peripheral blood. When viewed under a microscope, these cells appear to be covered with tiny hair-like projections.

CTEP Definition: CTEP_For_FDA: 10019053/Hairy cell leukemia

CSP Definition: neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of hairy or flagellated cells in the blood and bone marrow.

MSH Definition: A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of "hairy" or "flagellated" cells in the blood and bone marrow.

Synonyms & Abbreviations: (see Synonym Details)
Hairy-cell leukaemia
Hairy-cell leukemia
Hairy cell leukaemia
Hairy cell leukaemia (clinical)
HAIRY CELL LEUKEMIA
Hairy Cell Leukemias
Hairy cell leukemia (clinical)
Hairy cell leukemia (disorder)
Hairy cell leukemia (morphologic abnormality)
Hairy cell leukemia NOS
hairy T cell leukemia
HCL
HCL - Hairy cell leukaemia
HCL - Hairy cell leukemia
Leukaemic reticuloendotheliosis
Leukaemic reticuloendotheliosis (clinical) [obs]
Leukemia, Hairy Cell
Leukemia, Hairy Cell [Disease/Finding]
Leukemias, Hairy Cell
LEUKEMIA HAIRY CELL
Leukemic Reticuloendothelioses
Leukemic reticuloendotheliosis
Leukemic reticuloendotheliosis (clinical) [obs]
LRE - Leukaemic reticuloendotheliosis
LRE - Leukemic reticuloendotheliosis
Reticuloendothelioses, Leukemic
RETICULOENDOTHELIOSIS, LEUKEMIC

External Source Codes: 
NCI Thesaurus Code C7402 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN since the disease is chronic, do not coordinate with CHRONIC DISEASE; note entry term RETICULOENDOTHELIOSIS, LEUKEMIC;: RETICULOENDOTHELIOSIS, AVIAN is also available MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CODE_REF (C42.1) ICDO
Contributing_Source CTEP NCI
Contributing_Source CTRP NCI
CTV3ID B624. SNOMEDCT_US
CTV3ID BBrA8 SNOMEDCT_US
DATE_CREATED 2013-01-09T00:04:00 GARD
DATE_LAST_MODIFIED 2013-01-09T00:04:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2004-1799 CSP
DISEASE_IDENTIFIER_ID 18971 GARD
DISEASE_IDENTIFIER_ID 18972 GARD
DX 19780101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
HAS_GARD_PAGE true GARD
HN 78 MSH
IAN DEFAULT ICD10
ICD-O-3_Code 9940/3 NCI
ICD-O-3_CODE 9940/3 SNOMEDCT_US
ICE Hairy-cell leukemia ICD9CM
IDENTIFIER_TYPE_ID 1 GARD
INCLUSION_TERM Leukaemic reticuloendotheliosis ICD10
IS_ACTIVE true GARD
IS_RARE true GARD
IS_SPANISH false GARD
MDA 19770427 MSH
MESH_DEFINITION A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of "hairy" or "flagellated" cells in the blood and bone marrow. NDFRT
MESH_DUI D007943 NDFRT
MESH_NAME Leukemia, Hairy Cell NDFRT
MESH_UI M0012387 NDFRT
MMR 20090803 MSH
MN C04.557.337.415 MSH
MN C15.604.515.553 MSH
MN C20.683.515.517 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NCI_THESAURUS_CODE C7402 PDQ
NDFRT_KIND DISEASE_KIND NDFRT
Neoplastic_Status Malignant NCI
NUI N0000001820 NDFRT
ORDER_NO 02597 ICD10CM
ORIG_STY Neoplasm diagnosis PDQ
PID 1651 PDQ
PM 78 MSH
PRIMARY_PATH 10019053$10024295$10024324$10029104$Hairy cell leukaemia$Leukaemias chronic lymphocytic$Leukaemias$Neoplasms benign, malignant and unspecified (incl cysts and polyps) MDR
PRIMARY_SOC 10029104 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/6560/hairy-cell-leukemia/resources/1 GARD
RXAUI 3170819 RXNORM
RXAUI 3188875 RXNORM
RXAUI 3188876 RXNORM
RXAUI 3189149 RXNORM
RXAUI 3231816 RXNORM
RXCUI 1022561 RXNORM
SMQ_TERM_ADDVERSION 10.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 20.0 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 118613001 NDFRT
SNOMED_CID 188644003 NDFRT
SNOMEDID DC-F2300 SNOMEDCT_US
SNOMEDID M-99403 SNOMEDCT_US
SUBSET_MEMBER 446608001~MAPTARGET~9940/3 SNOMEDCT_US
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS C91.4 | POSSIBLE REQUIREMENT FOR MORPHOLOGY CODE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~C91.4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS C91.40 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~C91.40 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~B624. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~BBrA8 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~DC-F2300 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~M-99403 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERM_LEVEL 4 ICDO
TERM_LEVEL Synonym ICDO
TERMUI T023655 MSH
TERMUI T023656 MSH
TERMUI T023657 MSH
TERMUI T023658 MSH
TH NLM (1978) MSH
TH ORD (2010) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0023443

Mainbox Bottom