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Leprosy (CUI C0023343) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0023343

NCI Thesaurus Code: C84824  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A bacterial granulomatous infection caused by Mycobacterium leprae. It is a progressive disease affecting the skin, peripheral nerves, and limbs. If untreated, it causes permanent tissue damage leading to autoamputations.

GARD Definition: Hansen's disease (also known as leprosy) is a rare bacterial infection that affects the skin, nerves and mucous membranes. After exposure, it may take anywhere from 2 to 10 years to develop features of the condition. Once present, common signs and symptoms include skin lesions; muscle weakness or paralysis; eye problems that may lead to blindness; nosebleeds; severe pain; and/or numbness in the hands, feet, arms and legs. Hansen's disease is caused by the bacterium Mycobacterium leprae; however, the way in which the bacterium is transmitted (spread) is poorly understood. It appears that only about 5% of people are susceptible to the condition. Hansen's disease is easily treated with combination antibiotics for 6 months to 2 years. - this information is from GARD/ORDR/NCATS.

NICHD Definition: An infection predominantly that is caused by Mycobacterium leprae, which causes a progressive disease affecting the skin, peripheral nerves, and limbs. If untreated, it usually causes permanent tissue damage leading to autoamputations.

CSP Definition: chronic granulomatous infection caused by Mycobacterium leprae; granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves; two polar or principal types are lepromatous and tuberculoid.

MSH Definition: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.

Synonyms & Abbreviations: (see Synonym Details)
Disease, Hansen's
Disease, Hansen
HANSEN DISEASE
HANSEN DIS
Hansen's disease
Hansens Disease
HANSENS DIS
Infection due to Mycobacterium leprae
Leprosies
Leprosy (disorder)
Leprosy [Disease/Finding]
Leprosy [Hansen's disease]
Leprosy NOS
Leprosy, unspecified
leprosy
Leprous infections
Mycobacterium leprae infection NOS
Mycobacterium leprae infection

External Source Codes: 
NCI Thesaurus Code C84824 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN general or unspecified; prefer specifics; coordinate with NEGLECTED DISEASES if pertinent; rat leprosy = MYCOBACTERIUM INFECTIONS (IM) + MYCOBACTERIUM LEPRAEMURIUM (IM); ENL (erythema nodosum leprosum) = LEPROSY, LEPROMATOUS (IM) + ERYTHEMA NODOSUM (IM) MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH TM UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID A30.. SNOMEDCT_US
DATE_CREATED 2013-01-09T00:04:00 GARD
DATE_LAST_MODIFIED 2013-01-09T00:04:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 0368-2390 CSP
DISEASE_IDENTIFIER_ID 4117 GARD
DX 19660101 MSH
EFFECTIVE_TIME 20020731 SNOMEDCT_US
EXCLUDES1 sequelae of leprosy (B92) ICD10CM
FX D007917 MSH
HAS_GARD_PAGE true GARD
IAN DEFAULT ICD10
IDENTIFIER_TYPE_ID 1 GARD
INCLUSION_TERM infection due to Mycobacterium leprae ICD10
IS_ACTIVE true GARD
IS_RARE true GARD
IS_SPANISH false GARD
MDA 19990101 MSH
MESH_DEFINITION A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid. NDFRT
MESH_DUI D007918 NDFRT
MESH_NAME Leprosy NDFRT
MESH_UI M0012361 NDFRT
MMR 20121204 MSH
MN C01.252.410.040.552.386 MSH
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Leprosy NCI
NUI N0000001810 NDFRT
ORDER_NO 00211 ICD10CM
ORDER_NO 00219 ICD10CM
PRIMARY_PATH 10024229$10024230$10028440$10021881$Leprosy$Leprous infections$Mycobacterial infectious disorders$Infections and infestations MDR
PRIMARY_SOC 10021881 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/6886/hansens-disease/resources/1 GARD
RXAUI 3170970 RXNORM
RXAUI 3170971 RXNORM
RXAUI 3188645 RXNORM
RXAUI 3188646 RXNORM
RXCUI 1026701 RXNORM
SNOMED_CID 81004002 NDFRT
SOS Includes: Hansen's disease; infection by Mycobacterium leprae ICD9CM
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS A30.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~A30.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS A30.9 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~A30.9 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~A30.. SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T023601 MSH
TERMUI T023602 MSH
TERMUI T023603 MSH
TH NLM (1992) MSH
TH ORD (2010) MSH
TH POPLINE (1994) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0023343

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