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Actinic keratosis (CUI C0022602) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0022602

NCI Thesaurus Code: C3148  (see NCI Thesaurus info)

Semantic Type: Neoplastic Process

NCIt Definition: A precancerous lesion of the skin composed of atypical keratinocytes. It is characterized by the presence of thick, scaly patches of skin. Several histologic variants have been described, including atrophic, acantholytic, and hyperkeratotic variants.

PDQ Definition: A precancerous lesion of the skin composed of atypical keratinocytes. It is characterized by the presence of thick, scaly patches of skin. Several histologic variants have been described, including atrophic, acantholytic, and hyperkeratotic variants. Check for active clinical trials using this agent. (NCI Thesaurus)

NCI-GLOSS Definition: A thick, scaly patch of skin that may become cancer. It usually forms on areas exposed to the sun, such as the face, scalp, back of the hands, or chest. It is most common in people with fair skin.

MSH Definition: White or pink lesions on the arms, hands, face, or scalp that arise from sun-induced DNA DAMAGE to KERATINOCYTES in exposed areas. They are considered precursor lesions to superficial SQUAMOUS CELL CARCINOMA.

Synonyms & Abbreviations: (see Synonym Details)
Actinic (Solar) Keratosis
Actinic Keratoses
Actinic keratosis (disorder)
Actinic keratosis (morphologic abnormality)
ACTINIC KERATOSIS
AK - Actinic keratosis
Atrophic keratosis
Hyperplastic keratosis
Keratinocytic intraepidermal neoplasia
Keratoses, Actinic
Keratosis NOS
Keratosis, Actinic [Disease/Finding]
KERATOSIS, ACTINIC
Senile Hyperkeratosis
Senile keratoma
Senile keratosis
SENILE SOLAR KERATOSIS
SK - Solar keratosis
Solar keratosis

External Source Codes: 
NCI Thesaurus Code C3148 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source CTRP NCI
CTV3ID M226. SNOMEDCT_US
CTV3ID XUMNh SNOMEDCT_US
DATE_LAST_MODIFIED 2007-05-21 PDQ
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DX 20090101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20030731 SNOMEDCT_US
HN 2009 MSH
IAN DEFAULT ICD10
INCLUSION_TERM Keratosis: NOS ICD10
INCLUSION_TERM Keratosis: senile ICD10
INCLUSION_TERM Keratosis: solar ICD10
MDA 20080708 MSH
MESH_DEFINITION White or pink lesions on the arms, hands, face, or scalp that arise from sun-induced DNA DAMAGE to KERATINOCYTES in exposed areas. They are considered precursor lesions to superficial SQUAMOUS CELL CARCINOMA. NDFRT
MESH_DUI D055623 NDFRT
MESH_NAME Keratosis, Actinic NDFRT
MESH_UI M0518969 NDFRT
MN C04.834.450 MSH
MN C17.800.428.570 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MODULE_ID 731000124108 SNOMEDCT_US
MODULE_NAME US National Library of Medicine maintained module SNOMEDCT_US
NCI_THESAURUS_CODE C3148 PDQ
NDFRT_KIND DISEASE_KIND NDFRT
Neoplastic_Status Undetermined NCI
NUI N0000181025 NDFRT
ORDER_NO 14201 ICD10CM
ORIG_STY Disease/diagnosis PDQ
PID 1237 PDQ
PM 2009 MSH
PRIMARY_PATH 10000614$10052567$10011063$10040785$Actinic keratosis$Skin preneoplastic conditions NEC$Cornification and dystrophic skin disorders$Skin and subcutaneous tissue disorders MDR
PRIMARY_SOC 10040785 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3286623 RXNORM
RXAUI 3287680 RXNORM
RXAUI 3287681 RXNORM
RXCUI 1023186 RXNORM
SMQ_TERM_ADDVERSION 10.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 14.0 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_STATUS I MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMEDID M-72850 SNOMEDCT_US
SNOMEDID R-F8714 SNOMEDCT_US
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS L57.0 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~L57.0 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS L57.0 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~L57.0 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~M226. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUMNh SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~M-72850 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~R-F8714 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T715471 MSH
TERMUI T715472 MSH
TH NLM (2009) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0022602

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