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Juxtaglomerular Apparatus (CUI C0022445) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0022445

NCI Thesaurus Code: C32891  (see NCI Thesaurus info)

Semantic Type: Body Part, Organ, or Organ Component

NCIt Definition: Cellular population adjacent to the renal corpuscle, composed of the macula densa, the juxtaglomerular cells, and the extraglomerular mesangial cells. It regulates the blood pressure by activating the renin-angiotensin-aldosterone system.

CSP Definition: specialized cells containing secretory granules, located in the tunica media of the afferent glomerular arterioles; major structural component responsible for the release of renin; play a major role in renal autoregulation.

MSH Definition: A complex of cells consisting of juxtaglomerular cells, extraglomerular mesangium lacis cells, the macula densa of the distal convoluted tubule, and granular epithelial peripolar cells. Juxtaglomerular cells are modified SMOOTH MUSCLE CELLS found in the walls of afferent glomerular arterioles and sometimes the efferent arterioles. Extraglomerular mesangium lacis cells are located in the angle between the afferent and efferent glomerular arterioles. Granular epithelial peripolar cells are located at the angle of reflection of the parietal to visceral angle of the renal corpuscle.

Synonyms & Abbreviations: (see Synonym Details)
Apparatus, Juxtaglomerular
Juxtaglomerular apparatus structure (body structure)
Juxtaglomerular apparatus structure
juxtaglomerular apparatus
Juxtaglomerular complex

External Source Codes: 
NCI Thesaurus Code C32891 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AB AH BS CH CY DE DG EM EN GD IM IN IR ME MI PA PH PP PS RE SE SU TR UL VI MSH
AUTHORITY Bloom & Fawcett 94:746 FMA
AUTHORITY Unified Medical Language System FMA
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CTV3ID XS0ri SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 1680-2683 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FX D012083 MSH
HN 66(64) MSH
ICD-O-3_CODE C64.9 SNOMEDCT_US
MDA 19990101 MSH
MMR 20080708 MSH
MN A05.810.453.324.359.520 MSH
MN A05.810.453.736.520.520 MSH
PM 66 MSH
SUBSET_MEMBER 446608001~MAPTARGET~C64.9 SNOMEDCT_US
SUBSET_MEMBER 723264001 SNOMEDCT_US
SUBSET_MEMBER 734138000~TARGETCOMPONENT~362219002 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XS0ri SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T022834 MSH
TH NLM (1964) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0022445

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