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Infertility (CUI C0021359) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0021359

NCI Thesaurus Code: C3836  (see NCI Thesaurus info)

Semantic Type: Pathologic Function

NCIt Definition: Inability to conceive for at least one year after trying and having unprotected sex. Causes of female infertility include endometriosis, fallopian tubes obstruction, and polycystic ovary syndrome. Causes of male infertility include abnormal sperm production or function, blockage of the epididymis, blockage of the ejaculatory ducts, hypospadias, exposure to pesticides, and health related issues.

MEDLINEPLUS Definition: 

Infertility means not being able to become pregnant after a year of trying. If a woman can get pregnant but keeps having miscarriages or stillbirths, that's also called infertility.

Infertility is fairly common. After one year of having unprotected sex, about 15 percent of couples are unable to get pregnant. About a third of the time, infertility can be traced to the woman. In another third of cases, it is because of the man. The rest of the time, it is because of both partners or no cause can be found.

There are treatments that are specifically for men or for women. Some involve both partners. Drugs, assisted reproductive technology, and surgery are common treatments. Happily, many couples treated for infertility go on to have babies.

NIH: National Institute of Child Health and Human Development

NCI-GLOSS Definition: The inability to produce children.

MSH Definition: A reduced or absent capacity to reproduce.

Synonyms & Abbreviations: (see Synonym Details)
Cannot achieve a pregnancy
Difficulty conceiving
FERTILITY DISORDERS
fertility issues
Infertile (finding)
Infertile
Infertility [Disease/Finding]
Infertility NOS
infertility
Sterile
sterility

External Source Codes: 
NCI Thesaurus Code C3836 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN general or unspecified as male or female; prefer the specifics; PLANT INFERTILITY is available MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source CTRP NCI
CTV3ID X76Lv SNOMEDCT_US
DATE_CREATED 06/10/1999 MEDLINEPLUS
DATE_FIRST_PUBLISHED 2012-02-18 PDQ
DATE_LAST_MODIFIED 2012-04-08 PDQ
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 1138-0208 CSP
DX 19830101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
HN 83; was STERILITY 1963-82 MSH
HN ETOH descriptor 2000. AOD
MDA 19990101 MSH
MESH_DEFINITION Inability to reproduce after a specified period of unprotected intercourse. Reproductive sterility is permanent infertility. NDFRT
MESH_DUI D007246 NDFRT
MESH_NAME Infertility NDFRT
MESH_UI M0011302 NDFRT
MMR 20160616 MSH
MN C12.294.365 MSH
MN C13.351.500.365 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/infertility.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Arabic https://www.nlm.nih.gov/medlineplus/languages/infertility.html#Arabic MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Somali https://www.nlm.nih.gov/medlineplus/languages/infertility.html#Somali MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/infertility.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Child Health and Human Development http://www.nichd.nih.gov/ MEDLINEPLUS
NCI_THESAURUS_CODE C3836 PDQ
NDFRT_KIND DISEASE_KIND NDFRT
NUI N0000001684 NDFRT
OL use INFERTILITY to search STERILITY 1966-82 MSH
ORIG_STY Secondary related condition PDQ
PM 83; was STERILITY 1963-82 MSH
PRIMARY_PATH 10021926$10013357$10013356$10038604$Infertility$Sexual function and fertility disorders NEC$Sexual function and fertility disorders$Reproductive system and breast disorders MDR
PRIMARY_SOC 10038604 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3181002 RXNORM
RXAUI 3181003 RXNORM
RXCUI 1023984 RXNORM
SMQ_TERM_ADDVERSION 14.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 14.1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 8619003 NDFRT
SNOMEDID F-80410 SNOMEDCT_US
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~IF FEMALE CHOOSE N97.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~IF MALE CHOOSE N46 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~IFA 248152002 | Female (finding) | SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~IFA 248153007 | Male (finding) | SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~N46 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~N97.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF FEMALE CHOOSE N97.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFERTILITY CAUSED BY RADIATION AND IF FEMALE CHOOSE N97.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFERTILITY CAUSED BY RADIATION AND IF MALE CHOOSE N46.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFERTILITY CAUSED BY RADIATION CHOOSE T66.XXX? | EPISODE OF CARE INFORMATION NEEDED | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT | POSSIBLE REQUIREMENT FOR AN EXTERNAL CAUSE CODE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFERTILITY DUE TO DRUG THERAPY AND IF FEMALE CHOOSE N97.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFERTILITY DUE TO DRUG THERAPY AND IF MALE CHOOSE N46.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFERTILITY DUE TO DRUG THERAPY CHOOSE T50.905? | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | EPISODE OF CARE INFORMATION NEEDED | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFERTILITY DUE TO GERMINAL CELL APLASIA CHOOSE N46.01 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFERTILITY DUE TO INFECTION AND IF FEMALE CHOOSE N97.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFERTILITY DUE TO INFECTION AND IF MALE CHOOSE N46.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFERTILITY DUE TO INFECTION CHOOSE B99.9 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFERTILITY DUE TO SYSTEMIC DISEASE AND IF FEMALE CHOOSE N97.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFERTILITY DUE TO SYSTEMIC DISEASE AND IF MALE CHOOSE N46.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF MALE CHOOSE N46.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF PRIMARY INFERTILITY AND IF FEMALE CHOOSE N97.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF PRIMARY INFERTILITY AND IF MALE CHOOSE N46.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF SECONDARY INFERTILITY AND IF FEMALE CHOOSE N97.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF SECONDARY INFERTILITY AND IF MALE CHOOSE N46.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF UNEXPLAINED INFERTILITY AND IF FEMALE CHOOSE N97.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF UNEXPLAINED INFERTILITY AND IF MALE CHOOSE N46.9 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~10 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~11 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~12 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~13 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~14 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~15 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~16 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~17 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~18 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~19 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~5 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~6 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~7 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~8 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 21071002 | Infertility due to germinal cell aplasia (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 237145004 | Unexplained infertility (finding) | AND IFA 248152002 | Female (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 237145004 | Unexplained infertility (finding) | AND IFA 248153007 | Male (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 237145004 | Unexplained infertility (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 248152002 | Female (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 248153007 | Male (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 297106006 | Primary infertility (finding) | AND IFA 248152002 | Female (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 297106006 | Primary infertility (finding) | AND IFA 248153007 | Male (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 297106006 | Primary infertility (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 297121000 | Secondary infertility (finding) | AND IFA 248152002 | Female (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 297121000 | Secondary infertility (finding) | AND IFA 248153007 | Male (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 297121000 | Secondary infertility (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 52937008 | Infertility due to infection (finding) | AND IFA 248152002 | Female (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 52937008 | Infertility due to infection (finding) | AND IFA 248153007 | Male (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 52937008 | Infertility due to infection (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 53821008 | Infertility caused by radiation (finding) | AND IFA 248152002 | Female (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 53821008 | Infertility caused by radiation (finding) | AND IFA 248153007 | Male (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 53821008 | Infertility caused by radiation (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 58423003 | Infertility due to systemic disease (finding) | AND IFA 248152002 | Female (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 58423003 | Infertility due to systemic disease (finding) | AND IFA 248153007 | Male (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 58423003 | Infertility due to systemic disease (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 80330000 | Infertility due to drug therapy (finding) | AND IFA 248152002 | Female (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 80330000 | Infertility due to drug therapy (finding) | AND IFA 248153007 | Male (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 80330000 | Infertility due to drug therapy (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~B99.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~N46.01 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~N46.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~N97.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~T50.905? SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~T66.XXX? SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X76Lv SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~F-80410 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T021724 MSH
TH BIOETHICS (1974) MSH
TH NLM (1983) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0021359

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