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Hypogonadism (CUI C0020619) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0020619

NCI Thesaurus Code: C9227  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A disorder characterized by decreased function of the gonads. Clinical manifestations in both males and females include poor libido, infertility, and osteoporosis. Additional signs in males include erectile dysfunction, muscle atrophy, gynecomastia and increased abdominal fat. In females, additional signs include shrinking of the breasts and loss of, or failure to develop menstruation.

HPO Definition: A decreased functionality of the gonad. [HPO:curators]

NICHD Definition: Decreased or absent production of sex steroids by the ovaries or testes.

CSP Definition: condition resulting from or characterized by abnormally decreased functional activity of the gonads, with retardation of growth and sexual development.

MSH Definition: Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).

Synonyms & Abbreviations: (see Synonym Details)
Decreased activity of gonads
Gonadotropin Deficiency
Hypogonadism (disorder)
Hypogonadism [Disease/Finding]
hypogonadism
Hypogonadotropism

External Source Codes: 
NCI Thesaurus Code C9227 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN for male or female; do not routinely interpret hypogonadism in male as EUNUCHISM: use terminology of author MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID X40Ov SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2586-8835 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20070731 SNOMEDCT_US
HN 1966 MSH
HPO_COMMENT Reduced functioning of the gonads (ovaries or testes) with reduced production of sex hormones. HPO
MDA 19990101 MSH
MESH_DEFINITION Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism). NDFRT
MESH_DUI D007006 NDFRT
MESH_NAME Hypogonadism NDFRT
MESH_UI M0010905 NDFRT
MMR 20120703 MSH
MN C19.391.482 MSH
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Hypogonadism NCI
NUI N0000001636 NDFRT
PM 1966 MSH
PRIMARY_PATH 10058359$10014691$10014701$10014698$Hypogonadism$Endocrine abnormalities of gonadal function NEC$Endocrine disorders of gonadal function$Endocrine disorders MDR
PRIMARY_SOC 10014698 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
REF orcid.org/0000-0001-6908-9849 HPO
RXAUI 3174790 RXNORM
RXAUI 3174791 RXNORM
RXCUI 1025388 RXNORM
SMQ_TERM_ADDVERSION 14.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LMVERSION 14.1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 48130008 NDFRT
SNOMEDID DB-12702 SNOMEDCT_US
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~IF FEMALE CHOOSE E28.3 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~IF MALE CHOOSE E29.1 | MAP IS CONTEXT DEPENDENT FOR GENDER | POSSIBLE REQUIREMENT FOR AN EXTERNAL CAUSE CODE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~IFA 248152002 | Female (finding) | SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~IFA 248153007 | Male (finding) | SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~E28.3 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~E29.1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~DESCENDANTS NOT EXHAUSTIVELY MAPPED | MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF FEMALE CHOOSE E28.39 | DESCENDANTS NOT EXHAUSTIVELY MAPPED | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF MALE CHOOSE E29.1 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | DESCENDANTS NOT EXHAUSTIVELY MAPPED | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 248152002 | Female (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 248153007 | Male (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E28.39 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E29.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X40Ov SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~DB-12702 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T021003 MSH
TH NLM (1966) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0020619

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