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Hypoglycemia (CUI C0020615) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0020615

NCI Thesaurus Code: C3126  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: Abnormally low level of glucose in the blood.

RADLEX Definition: A syndrome of abnormally low blood glucose level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the central nervous system resulting in hunger; sweating; paresthesia; impaired mental function; seizures; coma; and even death. [MeSH]

HPO Definition: A decreased concentration of glucose in the blood. [HPO:curators]

MEDLINEPLUS Definition: 

Hypoglycemia means low blood glucose, or blood sugar. Your body needs glucose to have enough energy. After you eat, your blood absorbs glucose. If you eat more sugar than your body needs, your muscles, and liver store the extra. When your blood sugar begins to fall, a hormone tells your liver to release glucose.

In most people, this raises blood sugar. If it doesn't, you have hypoglycemia, and your blood sugar can be dangerously low. Signs include

  • Hunger
  • Shakiness
  • Dizziness
  • Confusion
  • Difficulty speaking
  • Feeling anxious or weak

In people with diabetes, hypoglycemia is often a side effect of diabetes medicines. Eating or drinking something with carbohydrates can help. If it happens often, your health care provider may need to change your treatment plan.

You can also have low blood sugar without having diabetes. Causes include certain medicines or diseases, hormone or enzyme deficiencies, and tumors. Laboratory tests can help find the cause. The kind of treatment depends on why you have low blood sugar.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

CTCAE Definition: A disorder characterized by laboratory test results that indicate a low concentration of glucose in the blood.

NCI-GLOSS Definition: Abnormally low blood sugar.

NICHD Definition: Abnormally low level of glucose in the blood.

CSP Definition: syndrome of abnormally low blood glucose level; clinical hypoglycemia has diverse etiologies; severe hypoglycemia eventually lead to glucose deprivation of the central nervous system resulting in hunger, sweating, paresthesia, impaired mental function, seizures, coma, and even death.

MSH Definition: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.

Synonyms & Abbreviations: (see Synonym Details)
Blood Glucose, Low
Glucose, Low Blood
Hypoglycaemia NOS
Hypoglycaemia, unspecified
HYPOGLYCAEMIA
Hypoglycaemic disorder
Hypoglycaemic syndrome
Hypoglycemia (disorder)
Hypoglycemia [Disease/Finding]
Hypoglycemia NOS
Hypoglycemia, unspecified
hypoglycemia
Hypoglycemic disorder (disorder)
Hypoglycemic disorder
Hypoglycemic syndrome (disorder)
Hypoglycemic syndrome
Hypoglykämie
Low Blood Glucose
Low blood sugar

External Source Codes: 
NCI Thesaurus Code C3126 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN for hypoglycemic effects caused by plants or extracts use HYPOGLYCEMIC AGENTS MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source CTCAE NCI
Contributing_Source CTRP NCI
Contributing_Source FDA NCI
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID X40Jn SNOMEDCT_US
CTV3ID Xa9Ao SNOMEDCT_US
CTV3ID XU3fz SNOMEDCT_US
DATE_CREATED 04/18/2000 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 0551-5561 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EXCLUDES1 diabetes with hypoglycemia (E08.649, E10.649, E11.649, E13.649) ICD10CM
EXTERNALLY_DEFINED N LNC
FDA_Table Patient Code (Appendix B) NCI
IAN DEFAULT ICD10
ICE Hypoglycemia: {NOS; reactive; spontaneous} ICD9CM
IPX -E15 ICPC
IPX -E16 ICPC
MDA 19990101 MSH
MESH_DEFINITION A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH. NDFRT
MESH_DUI D007003 NDFRT
MESH_NAME Hypoglycemia NDFRT
MESH_UI M0010901 NDFRT
MMR 20100625 MSH
MN C18.452.394.984 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/hypoglycemia.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Arabic https://www.nlm.nih.gov/medlineplus/languages/hypoglycemia.html#Arabic MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Simplified https://www.nlm.nih.gov/medlineplus/languages/hypoglycemia.html#Chinese - Simplified MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Traditional https://www.nlm.nih.gov/medlineplus/languages/hypoglycemia.html#Chinese - Traditional MEDLINEPLUS
MP_OTHER_LANGUAGE_URL French https://www.nlm.nih.gov/medlineplus/languages/hypoglycemia.html#French MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Hindi https://www.nlm.nih.gov/medlineplus/languages/hypoglycemia.html#Hindi MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Japanese https://www.nlm.nih.gov/medlineplus/languages/hypoglycemia.html#Japanese MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Korean https://www.nlm.nih.gov/medlineplus/languages/hypoglycemia.html#Korean MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Portuguese https://www.nlm.nih.gov/medlineplus/languages/hypoglycemia.html#Portuguese MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Russian https://www.nlm.nih.gov/medlineplus/languages/hypoglycemia.html#Russian MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Somali https://www.nlm.nih.gov/medlineplus/languages/hypoglycemia.html#Somali MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/hypoglycemia.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Ukrainian https://www.nlm.nih.gov/medlineplus/languages/hypoglycemia.html#Ukrainian MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Vietnamese https://www.nlm.nih.gov/medlineplus/languages/hypoglycemia.html#Vietnamese MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Diabetes and Digestive and Kidney Diseases http://www.niddk.nih.gov/ MEDLINEPLUS
NCI_THESAURUS_CODE C3126 PDQ
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Hypoglycemia NCI
NUI N0000001635 NDFRT
ORDER_NO 04283 ICD10CM
ORIG_STY Secondary related condition PDQ
PID 4463 PDQ
PRIMARY_PATH 10020993$10021001$10018424$10027433$Hypoglycaemia$Hypoglycaemic conditions NEC$Glucose metabolism disorders (incl diabetes mellitus)$Metabolism and nutrition disorders MDR
PRIMARY_SOC 10027433 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
REF orcid.org/0000-0001-5208-3432 HPO
RXAUI 3174781 RXNORM
RXAUI 3174782 RXNORM
RXCUI 1026036 RXNORM
SID HP:0003356 HPO
SMQ_TERM_ADDVERSION 19.0 MDR
SMQ_TERM_ADDVERSION 9.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 19.0 MDR
SMQ_TERM_LMVERSION 9.0 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 190433001 NDFRT
SNOMED_CID 237630007 NDFRT
SNOMED_CID 271327008 NDFRT
SNOMED_CID 302866003 NDFRT
SOS Excludes: hypoglycemia: {with coma (251.0); in diabetes mellitus (249.8, 250.8)}; leucine-induced (270.3) ICD9CM
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS E16.1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS E16.2 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~E16.1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~E16.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS E16.2 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS E16.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF AGE AT ONSET OF CLINICAL FINDING BEFORE 1.0 YEAR CHOOSE E16.1 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF ALIMENTARY HYPOGLYCEMIA CHOOSE E16.1 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF IATROGENIC NEONATAL HYPOGLYCEMIA CHOOSE P70.3 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF LATE DUMPING SYNDROME CHOOSE K91.1 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF NEONATAL HYPOGLYCEMIA CHOOSE P70.4 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF POST GASTROINTESTINAL TRACT SURGERY HYPOGLYCEMIA CHOOSE E16.1 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF POST GASTROINTESTINAL TRACT SURGERY HYPOGLYCEMIA CHOOSE T81.9XX? | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | EPISODE OF CARE INFORMATION NEEDED | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~5 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~6 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~7 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 197483008 | Post gastrointestinal tract surgery hypoglycemia | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 235667000 | Late dumping syndrome | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 237639008 | Alimentary hypoglycemia | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 276562001 | Iatrogenic neonatal hypoglycemia | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 445518008 | Age at onset of clinical finding (observable entity) | < 1.0 year SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 52767006 | Neonatal hypoglycemia | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E16.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E16.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~K91.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~P70.3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~P70.4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~T81.9XX? SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X40Jn SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~Xa9Ao SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU3fz SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T020995 MSH
TH NLM (1966) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

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