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Hypersensitivity (CUI C0020517) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0020517

NCI Thesaurus Code: C3114  (see NCI Thesaurus info)

Semantic Type: Pathologic Function

NCIt Definition: An immune response that occurs following exposure to an innocuous antigen, but that does not require the presence of preformed antibodies to the antigen.

GO Definition: An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system. [GOC:jal, ISBN:0781735149]

SNOMEDCT_US Definition: A pathological process initiated by exposure to a defined stimulus at a dose tolerated by normal persons. It may be the manifestation of a disposition to hypersensitivity.

SNOMEDCT_US Definition: The disposition to develop an allergic reaction.

MEDLINEPLUS Definition: 

An allergy is a reaction by your immune system to something that does not bother most other people. People who have allergies often are sensitive to more than one thing. Substances that often cause reactions are

Normally, your immune system fights germs. It is your body's defense system. In most allergic reactions, however, it is responding to a false alarm. Genes and the environment probably both play a role.

Allergies can cause a variety of symptoms such as a runny nose, sneezing, itching, rashes, swelling, or asthma. Allergies can range from minor to severe. Anaphylaxis is a severe reaction that can be life-threatening. Doctors use skin and blood tests to diagnose allergies. Treatments include medicines, allergy shots, and avoiding the substances that cause the reactions.

NIH: National Institute of Allergy and Infectious Diseases

NICHD Definition: An excessive immune system response to a substance that is not usually considered harmful.

NCI-GLOSS Definition: An exaggerated response by the immune system to a drug or other substance.

FDA Definition: Hypersensitivity; a local or general reaction of an organism following contact with a specific allergen to which it has been previously exposed and to which it has become sensitized.

CSP Definition: state of previously immunized body in which tissue damage results from the immune response to a further dose of antigen.

MSH Definition: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.

Synonyms & Abbreviations: (see Synonym Details)
Allergic disorders
Allergic disposition (disorder)
Allergic disposition
Allergic reactions
Allergic Reaction
Allergies
Allergy, unspecified
Allergy
Hypersensitive
Hypersensitivities
Hypersensitivity [Disease/Finding]
Hypersensitivity NOS
Hypersensitivity reaction (disorder)
HYPERSENSITIVITY REACTION (NOS)
Hypersensitivity reaction
Hypersensitivity symptom
hypersensitivity
HYSN
REACTION HYPERSENSITIVITY (NOS)
Sensitive
Sensitivity

External Source Codes: 
NCI Thesaurus Code C3114 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN IM; use qualif with caution; /drug ther: consider also ANTI-ALLERGIC AGENTS; atopic = HYPERSENSITIVITY, IMMEDIATE; to food = FOOD HYPERSENSITIVITY; to light = PHOTOSENSITIVITY DISORDERS; RESPIRATORY HYPERSENSITIVITY is also available; in occup or environ exposure MULTIPLE CHEMICAL SENSITIVITY is also available MSH
AQL BL CF CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source FDA NCI
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID XUdqG SNOMEDCT_US
CTV3ID XUm5p SNOMEDCT_US
DATE_CREATED 10/22/1998 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 1524-8093 CSP
DX 19660101 MSH
EC chemically induced:Drug Hypersensitivity MSH
EFFECTIVE_TIME 20130731 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
FDA_Table Patient Code (Appendix B) NCI
FX D003888 MSH
FX D018777 MSH
FX D018926 MSH
GO_NAMESPACE biological_process GO
GXR Wikipedia:Hypersensitivity GO
HN 66; was ALLERGY 1963-65 MSH
MDA 19990101 MSH
MESH_DEFINITION Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen. NDFRT
MESH_DUI D006967 NDFRT
MESH_NAME Hypersensitivity NDFRT
MESH_UI M0010851 NDFRT
MMR 19991103 MSH
MN C20.543 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MODULE_ID 731000124108 SNOMEDCT_US
MODULE_NAME US National Library of Medicine maintained module SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/allergy.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Simplified https://www.nlm.nih.gov/medlineplus/languages/allergy.html#Chinese - Simplified MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Traditional https://www.nlm.nih.gov/medlineplus/languages/allergy.html#Chinese - Traditional MEDLINEPLUS
MP_OTHER_LANGUAGE_URL French https://www.nlm.nih.gov/medlineplus/languages/allergy.html#French MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Hindi https://www.nlm.nih.gov/medlineplus/languages/allergy.html#Hindi MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Japanese https://www.nlm.nih.gov/medlineplus/languages/allergy.html#Japanese MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Korean https://www.nlm.nih.gov/medlineplus/languages/allergy.html#Korean MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Russian https://www.nlm.nih.gov/medlineplus/languages/allergy.html#Russian MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Somali https://www.nlm.nih.gov/medlineplus/languages/allergy.html#Somali MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/allergy.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Ukrainian https://www.nlm.nih.gov/medlineplus/languages/allergy.html#Ukrainian MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Allergy and Infectious Diseases http://www.niaid.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Hypersensitivity Reaction NCI
NUI N0000001610 NDFRT
ORDER_NO 80201 ICD10CM
PM 66; was ALLERGY 1963-65 MSH
PRIMARY_PATH 10020751$10027654$10001708$10021428$Hypersensitivity$Allergic conditions NEC$Allergic conditions$Immune system disorders MDR
PRIMARY_SOC 10021428 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3107743 RXNORM
RXAUI 3174503 RXNORM
RXAUI 3174512 RXNORM
RXCUI 1022134 RXNORM
SMQ_TERM_ADDVERSION 16.0 MDR
SMQ_TERM_ADDVERSION 19.0 MDR
SMQ_TERM_ADDVERSION 8.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_CAT B MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 16.0 MDR
SMQ_TERM_LMVERSION 19.0 MDR
SMQ_TERM_LMVERSION 8.1 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 106190000 NDFRT
SNOMED_CID 127072000 NDFRT
SNOMED_CID 269284003 NDFRT
SNOMEDID DF-00C3D SNOMEDCT_US
SNOMEDID F-04E21 SNOMEDCT_US
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS T78.4 | POSSIBLE REQUIREMENT FOR AN EXTERNAL CAUSE CODE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~T78.4 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS T78.40X? | DESCENDANTS NOT EXHAUSTIVELY MAPPED | EPISODE OF CARE INFORMATION NEEDED | POSSIBLE REQUIREMENT FOR AN EXTERNAL CAUSE CODE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~T78.40X? SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUdqG SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUm5p SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~DF-00C3D SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~F-04E21 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T020919 MSH
TERMUI T020920 MSH
TH NLM (1966) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

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