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Hyperprolactinemia (CUI C0020514) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0020514

NCI Thesaurus Code: C113168  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: Abnormally high level of prolactin in the blood.

HPO Definition: The presence of abnormally increased levels of prolactin in the blood. Prolactin is a peptide hormone produced by the anterior pituitary gland that plays a role in breast development and lactation during pregnancy. [DDD:spark, HPO:probinson]

NICHD Definition: Supranormal concentration of prolactin.

CSP Definition: increased levels of prolactin in the blood, which may be associated with amenorrhea and galactorrhea; relatively common etiologies include prolactinoma, medication effect, kidney failure, granulomatous diseases of the pituitary gland, and disorders which interfere with the hypothalamic inhibition of prolactin release; ectopic (non-pituitary) production of prolactin may also occur.

MSH Definition: Increased levels of PROLACTIN in the BLOOD, which may be associated with AMENORRHEA and GALACTORRHEA. Relatively common etiologies include PROLACTINOMA, medication effect, KIDNEY FAILURE, granulomatous diseases of the PITUITARY GLAND, and disorders which interfere with the hypothalamic inhibition of prolactin release. Ectopic (non-pituitary) production of prolactin may also occur. (From Joynt, Clinical Neurology, 1992, Ch36, pp77-8)

Synonyms & Abbreviations: (see Synonym Details)
HPRL
HYPERPROLACTINAEMIA
Hyperprolactinemia (disorder)
Hyperprolactinemia [Disease/Finding]
Hyperprolactinemias
hyperprolactinemia
Hypersecretion Syndrome, Prolactin
INAPPROPRIATE PROLACTIN SECRET SYNDROME
Inappropriate Prolactin Secretion Syndrome
Inappropriate Prolactin Secretion
INAPPROPRIATE PROLACTIN SECRET
Inappropriate Secretion Prolactin
Prolactin excess
PROLACTIN HYPERSECRET SYNDROME
Prolactin Hypersecretion Syndrome
PROLACTIN INAPPROPRIATE SECRET
Prolactin Secretion, Inappropriate
Prolactin, Inappropriate Secretion
Secretion Prolactin, Inappropriate
Secretion, Inappropriate Prolactin
Syndrome, Prolactin Hypersecretion

External Source Codes: 
NCI Thesaurus Code C113168 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID X40KY SNOMEDCT_US
DATE_CREATED 2013-01-09T00:04:00 GARD
DATE_LAST_MODIFIED 2013-01-09T00:04:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2335-9353 CSP
DISEASE_IDENTIFIER_ID 12026 GARD
DX 19860101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
GENELOCUS ,5,p,1,3,.,2, OMIM
GENESYMBOL HPRL OMIM
GENESYMBOL MFAB OMIM
GENESYMBOL PRLR OMIM
HN 1986 MSH
IAN DEFAULT ICD10
IDENTIFIER_TYPE_ID 1 GARD
IS_ACTIVE true GARD
MDA 19850311 MSH
MESH_DEFINITION Increased levels of PROLACTIN in the BLOOD, which may be associated with AMENORRHEA and GALACTORRHEA. Relatively common etiologies include PROLACTINOMA, medication effect, KIDNEY FAILURE, granulomatous diseases of the PITUITARY GLAND, and disorders which interfere with the hypothalamic inhibition of prolactin release. Ectopic (non-pituitary) production of prolactin may also occur. (From Joynt, Clinical Neurology, 1992, Ch36, pp77-8) NDFRT
MESH_DUI D006966 NDFRT
MESH_NAME Hyperprolactinemia NDFRT
MESH_UI M0010850 NDFRT
MIMTYPE 3 OMIM
MIMTYPEMEANING Phenotype description, molecular basis known. OMIM
MIMTYPEVALUE pound OMIM
MMR 20100625 MSH
MN C10.228.140.617.738.250.450 MSH
MN C19.700.355.600 MSH
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Hyperprolactinemia NCI
NUI N0000001609 NDFRT
ORDER_NO 04302 ICD10CM
PM 1986 MSH
PRIMARY_PATH 10020737$10002700$10021112$10014698$Hyperprolactinaemia$Anterior pituitary hyperfunction$Hypothalamus and pituitary gland disorders$Endocrine disorders MDR
PRIMARY_SOC 10014698 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3174464 RXNORM
RXAUI 3174465 RXNORM
RXAUI 3178801 RXNORM
RXAUI 3178802 RXNORM
RXAUI 3224009 RXNORM
RXAUI 3224029 RXNORM
RXAUI 3605901 RXNORM
RXCUI 1024103 RXNORM
SNOMED_CID 237662005 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS E22.1 | POSSIBLE REQUIREMENT FOR AN EXTERNAL CAUSE CODE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~E22.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS E22.1 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E22.1 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X40KY SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T020918 MSH
TERMUI T368520 MSH
TERMUI T368521 MSH
TERMUI T368522 MSH
TERMUI T368523 MSH
TERMUI T735933 MSH
TH NLM (1986) MSH
TH NLM (2000) MSH
TH NLM (2011) MSH
TH ORD (2010) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
USE_ADDITIONAL code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) ICD10CM

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0020514

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