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Hydroquinone (CUI C0020306) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0020306

NCI Thesaurus Code: C29823  (see NCI Thesaurus info)

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

NCIt Definition: Produced as an inhibitor, an antioxidant, and an intermediate in the synthesis of dyes, motor fuels, and oils; in photographic processing; and naturally in certain plant species, Hydroquinone is a phenol derivative with antioxidant properties that can cause toxicity in several organs, notably the kidney. Used as a topical treatment for skin hyperpigmentation and in various cosmetic products, it is metabolized mainly to glutathione conjugates and forms mutagenic DNA adducts in in-vitro systems. (NCI04)

CSP Definition: 1,4-dihydroxybenzene.

Synonyms & Abbreviations: (see Synonym Details)
1,4 benzenediol
1,4-benzenediol
1,4-dihydroxybenzene
Benzoquinol
beta-quinol
Hydroquinol
Hydroquinone (substance)
hydroquinone [Chemical/Ingredient]
hydroquinone
p-Dihydroxybenzene
Para-dihydroxybenzene
Product containing hydroquinone (medicinal product)
Product containing hydroquinone
quinol

External Source Codes: 
NCI Thesaurus Code C29823 (see NCI Thesaurus info)
CAS Registry Number 123-31-9 (see NLM ChemIDplus info)
FDA UNII Code XV74C1N1AE
NSC Code 9247 (see NCI DTP info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:17594 NCI
Chemical_Formula C6H6O2 NCI
Contributing_Source FDA NCI
CTV3ID mq1.. SNOMEDCT_US
CTV3ID XUWw7 SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2532-3296 CSP
EFFECTIVE_TIME 20030131 SNOMEDCT_US
EFFECTIVE_TIME 20160131 SNOMEDCT_US
FDA_UNII_CODE XV74C1N1AE DRUGBANK
FDA_UNII_CODE XV74C1N1AE NDFRT
FR 1476 MSH
HM D006873 MSH
LEVEL Ingredient NDFRT
MDA 19811113 MSH
MESH_DUI C031927 NDFRT
MESH_NAME hydroquinone NDFRT
MESH_UI M0099980 NDFRT
MMR 20141027 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000007082 NDFRT
NUI N0000147180 NDFRT
PA D000975 MSH
PA D009153 MSH
PA D011837 MSH
RN 123-31-9 MSH
RR 57218-73-2 (Pb(2+)[2:1] salt) MSH
RR 62723-60-8 (Cu(1+) salt) MSH
RR 64887-62-3 (mono-Cu(2+) salt) MSH
RXAUI 172807 RXNORM
RXAUI 2071476 RXNORM
RXAUI 2937483 RXNORM
RXAUI 3091277 RXNORM
RXAUI 3170331 RXNORM
RXAUI 3170332 RXNORM
RXAUI 3259225 RXNORM
RXAUI 3260890 RXNORM
RXAUI 3260891 RXNORM
RXAUI 3279241 RXNORM
RXAUI 3279292 RXNORM
RXCUI 5509 RXNORM
SC 1 MSH
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SRC Biochim Biophys Acta 1981;665(2):234 MSH
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SUBSET_MEMBER 900000000000497000~MAPTARGET~XUWw7 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T129983 MSH
TERMUI T129984 MSH
TERMUI T426685 MSH
TH NLM (1981) MSH
TH NLM (2000) MSH
TH USAN (1982) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^1490^Active/Master NDFRT
VANDF_RECORD 50.6^1285^Active/Master NDFRT
VUID 4018886 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0020306

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