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Horner Syndrome (CUI C0019937) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0019937

NCI Thesaurus Code: C28155  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: Interruption of sympathetic innervation to eye and face.

GARD Definition: Horner's syndrome consists of miosis (constriction of the pupil), ptosis (drooping of the upper eyelid), and anhidrosis (absence of sweating of the face).   It is caused by injury to the sympathetic nerves of the face. In rare cases, Horner's syndrome is congenital (present from birth) and associated with a lack of pigmentation of the iris (colored part of the eye). - this information is from GARD/ORDR/NCATS.

HPO Definition: An abnormality resulting from a lesion of the sympathetic nervous system characterized by a combination of unilateral ptosis, miosis, and often ipsilateral hypohidrosis and conjunctival injection. [HPO:probinson]

NCI-GLOSS Definition: A condition in which one side of the face is flushed, does not produce sweat, and has a constricted pupil and drooping eyelid. It can be caused by an injury to, or paralysis of, nerves in the neck, or by a tumor.

NICHD Definition: Interruption of sympathetic nerve innervation to eye and face.

CSP Definition: syndrome associated with defective sympathetic innervation to one side of the face, including the eye; clinical features include miosis, mild blepharoptosis, and hemifacial anhidrosis (decreased sweating); lesions of the brain stem, cervical spinal cord, first thoracic nerve root, apex of the lung, carotid artery, cavernous sinus, and apex of the orbit may cause this condition.

MSH Definition: A syndrome associated with defective sympathetic innervation to one side of the face, including the eye. Clinical features include MIOSIS; mild BLEPHAROPTOSIS; and hemifacial ANHIDROSIS (decreased sweating)(see HYPOHIDROSIS). Lesions of the BRAIN STEM; cervical SPINAL CORD; first thoracic nerve root; apex of the LUNG; CAROTID ARTERY; CAVERNOUS SINUS; and apex of the ORBIT may cause this condition. (From Miller et al., Clinical Neuro-Ophthalmology, 4th ed, pp500-11)

Synonyms & Abbreviations: (see Synonym Details)
Bernard Horner syndrome
Bernard Syndromes
Bernard Syndrome
Bernard's syndrome
Bernard(-Horner) syndrome
Bernard-Horner Syndrome
Bernards Syndrome
Cervical sympathetic paralysis (disorder)
CERVICAL SYMPATHETIC PARALYSIS SYNDROME
Cervical sympathetic paralysis
Claude Bernard Horner Syndrome
CLAUDE BERNARD-HORNER SYNDROME
Horner Syndrome [Disease/Finding]
HORNER SYNDROME
Horner's Syndrome
Horners Syndrome
Ocular Ophthalmoplegia, Sympathetic
Ocular Ophthalmoplegias, Sympathetic
Ocular-Ophthalmoplegia, Sympathetic
Ocular-Ophthalmoplegias, Sympathetic
Oculosympathetic Palsy
Oculosympathetic Syndromes
Oculosympathetic Syndrome
Ophthalmoplegia, Sympathetic Ocular
OPHTHALMOPLEGIA, SYMPATHETIC
Ophthalmoplegias, Sympathetic Ocular
Sympathetic Ocular Ophthalmoplegias
Sympathetic Ocular Ophthalmoplegia
Sympathetic Ocular-Ophthalmoplegias
Sympathetic Ocular-Ophthalmoplegia
Syndrome, Bernard's
Syndrome, Bernard
Syndrome, Claude Bernard-Horner
Syndrome, Horner's
Syndrome, Horner
Syndrome, Oculosympathetic
Syndromes, Bernard
Syndromes, Oculosympathetic

External Source Codes: 
NCI Thesaurus Code C28155 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID F1701 SNOMEDCT_US
DATE_CREATED 2013-01-09T00:04:00 GARD
DATE_LAST_MODIFIED 2013-01-09T00:04:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 1114-9021 CSP
DISEASE_IDENTIFIER_ID 19078 GARD
DISEASE_IDENTIFIER_ID 19079 GARD
DX 20000101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
HAS_GARD_PAGE true GARD
HN 2000(1966) MSH
HPO_COMMENT Ptosis, miosis, and occasionally apparent enophthalmos and anhidrosis on one side of the face, loss of ciliospinal reflex and blood shot conjunctiva. HPO
IAN DEFAULT ICD10
IDENTIFIER_TYPE_ID 1 GARD
INCLUSION_TERM Bernard(-Horner) syndrome ICD10
IS_ACTIVE true GARD
IS_RARE true GARD
IS_SPANISH false GARD
MDA 19990101 MSH
MESH_DEFINITION A syndrome associated with defective sympathetic innervation to one side of the face, including the eye. Clinical features include MIOSIS; mild BLEPHAROPTOSIS; and hemifacial ANHIDROSIS (decreased sweating)(see HYPOHIDROSIS). Lesions of the BRAIN STEM; cervical SPINAL CORD; first thoracic nerve root; apex of the LUNG; CAROTID ARTERY; CAVERNOUS SINUS; and apex of the ORBIT may cause this condition. (From Miller et al., Clinical Neuro-Ophthalmology, 4th ed, pp500-11) NDFRT
MESH_DUI D006732 NDFRT
MESH_NAME Horner Syndrome NDFRT
MESH_UI M0010542 NDFRT
MMR 19991130 MSH
MN C10.177.350 MSH
MN C10.597.690.362.500 MSH
MN C11.710.528.500 MSH
MN C23.888.592.708.362.500 MSH
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Horner Syndrome NCI
NUI N0000001555 NDFRT
ORDER_NO 06474 ICD10CM
PM 2000; see HORNER'S SYNDROME 1966-1999 MSH
PRIMARY_PATH 10020392$10003839$10029317$10029205$Horner's syndrome$Autonomic nervous system disorders$Neuromuscular disorders$Nervous system disorders MDR
PRIMARY_SOC 10029205 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/6670/horners-syndrome/resources/1 GARD
REF http://orcid.org/0000-0001-5208-3432 HPO
RXAUI 3117451 RXNORM
RXAUI 3117453 RXNORM
RXAUI 3133769 RXNORM
RXAUI 3173412 RXNORM
RXAUI 3173413 RXNORM
RXAUI 3173417 RXNORM
RXAUI 3209833 RXNORM
RXAUI 3210347 RXNORM
RXAUI 3241906 RXNORM
RXCUI 1022520 RXNORM
SID HP:0000596 HPO
SNOMED_CID 192915005 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS G90.2 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~G90.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS G90.09 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G90.09 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~F1701 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T020316 MSH
TERMUI T020317 MSH
TERMUI T365364 MSH
TERMUI T365365 MSH
TERMUI T365366 MSH
TERMUI T365367 MSH
TERMUI T365368 MSH
TERMUI T373520 MSH
TH NLM (1966) MSH
TH NLM (1990) MSH
TH NLM (2000) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0019937

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