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Hemoglobin SC Disease (CUI C0019034) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0019034

NCI Thesaurus Code: C34676  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A hemoglobinopathy that is considered a hybrid of sickle cell disease and hemoglobin C disease. Patients present with the symptoms of sickle cell disease but the latter are less frequent and severe compared to sickle cell disease.

NICHD Definition: A variant of sickle cell disease due to heterozygosity for hemoglobin S and hemoglobin C mutations. Patients present with the symptoms of sickle cell disease but the symptoms are less frequent and severe compared to patients with full sickle cell disease.

MSH Definition: One of the sickle cell disorders characterized by the presence of both hemoglobin S and hemoglobin C. It is similar to, but less severe than sickle cell anemia.

Synonyms & Abbreviations: (see Synonym Details)
Disease, Hemoglobin SC
Disease, SC
Diseases, Hemoglobin SC
Diseases, SC
Double heterozygous for Hb S and Hb D
Haemoglobin S-C disease
Haemoglobin S/C disease
Haemoglobin SC disease
Hb SC disease
Hb SC-disease
Hb-S/Hb-C disease
Hb-SC disease
Hb-SC
Hb-SS/hb-C dis w/o crsis
HbS-HbC disease
HbSC disease
Hemoglobin S-C disease
Hemoglobin S/C disease
Hemoglobin SC Disease [Disease/Finding]
Hemoglobin SC Diseases
Hemoglobin SC disease
HEMOGLOBIN SC DIS
SC Disease, Hemoglobin
SC Diseases, Hemoglobin
SC Diseases
SC Disease
SC DIS
Sickle cell - hemoglobin C disease
Sickle cell anaemia with haemoglobin C disease
Sickle cell anemia with hemoglobin C disease
Sickle cell haemoglobin C
Sickle cell Hb-C disease
Sickle Cell Hemoglobin C Disease
SICKLE CELL HEMOGLOBIN C DIS
Sickle cell hemoglobin C
Sickle cell-haemoglobin C disease
Sickle cell-hemoglobin C disease (disorder)
SICKLE CELL-HEMOGLOBIN C DISEASE
Sickle-cell/Hb-C disease without crisis
Sickle-cell/Hb-C disease

External Source Codes: 
NCI Thesaurus Code C34676 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN a sickle cell anemia; do not use /congen & do not coord with INFANT, NEWBORN, DISEASES; do not confuse with HEMOGLOBIN C DISEASE MSH
AQL BL CF CI CL CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID D1063 SNOMEDCT_US
DATE_CREATED 2015-01-20T00:03:00 GARD
DATE_LAST_MODIFIED 2015-01-20T00:03:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DISEASE_IDENTIFIER_ID 29690 GARD
DISEASE_IDENTIFIER_ID 29692 GARD
DX 19910101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
GLOBAL_ID 35434009 LNC
GLOBAL_ID_CODE_SYSTEM SCT LNC
HAS_GARD_PAGE true GARD
HN 91(84); was see under ANEMIA, SICKLE CELL 1984-90 MSH
ICE Hb-S/Hb-C disease ICD9CM
IDENTIFIER_SOURCE Orp GARD
IDENTIFIER_TYPE_ID 1 GARD
IS_ACTIVE true GARD
IS_RARE true GARD
IS_SPANISH false GARD
LAST_REVIEW_ACTION Related Disease Added GARD
MDA 19830503 MSH
MESH_DEFINITION One of the sickle cell disorders characterized by the presence of both hemoglobin S and hemoglobin C. It is similar to, but less severe than sickle cell anemia. NDFRT
MESH_DUI D006450 NDFRT
MESH_NAME Hemoglobin SC Disease NDFRT
MESH_UI M0010124 NDFRT
MMR 20010725 MSH
MN C15.378.071.141.150.150.440 MSH
MN C15.378.420.155.440 MSH
MN C16.320.070.150.440 MSH
MN C16.320.365.155.440 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Hemoglobin SC Disease NCI
NUI N0000001471 NDFRT
ORDER_NO 03378 ICD10CM
ORDER_NO 03379 ICD10CM
PM 91; was see under ANEMIA, SICKLE CELL 1984-90 MSH
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/6584/hemoglobin-sc-disease/resources/1 GARD
RXAUI 3171779 RXNORM
RXAUI 3171780 RXNORM
RXAUI 3233323 RXNORM
RXAUI 3238184 RXNORM
RXCUI 1023928 RXNORM
SMQ_TERM_ADDVERSION 10.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 14.0 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 35434009 NDFRT
SNOMEDID DC-20410 SNOMEDCT_US
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS D57.2 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~D57.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS D57.20 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF SICKLE CELL-HEMOGLOBIN C DISEASE WITH CRISIS CHOOSE D57.219 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 417517009 | Sickle cell-hemoglobin C disease with crisis (disorder) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~D57.20 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~D57.219 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~D1063 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~DC-20410 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T019476 MSH
TERMUI T019477 MSH
TERMUI T019478 MSH
TH NLM (1984) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0019034

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