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Membranous glomerulonephritis (CUI C0017665) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0017665

NCI Thesaurus Code: C34645  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A slowly progressive inflammation of the glomeruli characterized by immune complex deposits at the glomerular basement membrane, resulting in a thickened membrane, and nephrotic syndrome.

GARD Definition: Membranous nephropathy is a kidney disease characterized by inflammation of the structures inside the kidney that help filter wastes and fluids. When the glomerular basement membrane becomes thickened, it does not work normally, allowing large amounts of protein to be lost in the urine. Symptoms develop gradually and may include swelling, fatigue, weight gain, and high blood pressure. In many cases, the underlying cause of membranous nephropathy is not known. Some cases are associated with other conditions (lupus), infections (hepatitis B and C), cancer or as a side effect of certain medications. The goal of treatment is to reduce symptoms and slow the progression of the disease.  
- this information is from GARD/ORDR/NCATS.

HPO Definition: A type of glomerulonephropathy characterized by thickening of the basement membrane and deposition of immune complexes in the subepithelial space. [Eurenomics:fschaefer]

NICHD Definition: A condition characterized by thickening of the glomerular basement membrane, resulting from subepithelial or intramembranous immune complex deposition.

CSP Definition: characterized histologically by proteinaceous deposits on the glomerular capillary basement membrane or by thickening of the membrane; clinically similar to chronic glomerulonephritis, occasionally with transient nephrotic syndrome.

MSH Definition: A type of glomerulonephritis that is characterized by the accumulation of immune deposits (COMPLEMENT MEMBRANE ATTACK COMPLEX) on the outer aspect of the GLOMERULAR BASEMENT MEMBRANE. It progresses from subepithelial dense deposits, to basement membrane reaction and eventual thickening of the basement membrane.

Synonyms & Abbreviations: (see Synonym Details)
Chronic nephritic syndrome w diffuse membranous glomrlneph
Chronic nephritic syndrome with diffuse membranous glomerulonephritis
Chronic nephritic syndrome, diffuse membranous glomerulonephritis
Chronic nephritic syndrome; Diffuse membranous glomerulonephritis
Extramembranous glomerulonephritis
Extramembranous Glomerulopathy
Glomerulonephritides, Membranous
Glomerulonephritis membranous
Glomerulonephritis, Membranous [Disease/Finding]
GLOMERULONEPHRITIS, MEMBRANOUS
Glomerulonephropathy, Membranous
Glomerulopathy, Extramembranous
GLOMERULOPATHY, MEMBRANOUS
Membranous Glomerulonephritides
Membranous glomerulonephritis (disorder)
Membranous glomerulonephritis NOS
membranous glomerulonephritis
Membranous Glomerulonephropathy
Membranous Glomerulopathy
Membranous GN
Membranous nephropathy NOS
membranous nephropathy
MGN - Membranous glomerulonephritis
MGN
NEPHROPATHY, MEMBRANOUS

External Source Codes: 
NCI Thesaurus Code C34645 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN do not confuse with GLOMERULONEPHRITIS, MEMBRANOPROLIFERATIVE; do not make diagnoses: use the term used by the author MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID K021. SNOMEDCT_US
DATE_CREATED 2013-01-09T00:04:00 GARD
DATE_CREATED 2014-01-16T01:22:41Z HPO
DATE_LAST_MODIFIED 2013-01-09T00:04:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 4006-0062 CSP
DISEASE_IDENTIFIER_ID 19573 GARD
DISEASE_IDENTIFIER_ID 19574 GARD
DISEASE_IDENTIFIER_ID 19575 GARD
DISEASE_IDENTIFIER_ID 19576 GARD
DISEASE_IDENTIFIER_ID 19577 GARD
DX 19890101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
HAS_GARD_PAGE true GARD
HN 1989; for HEYMANN NEPHRITIS use GLOMERULONEPHRITIS 1987-2006 MSH
IAN DEFAULT ICD10
IDENTIFIER_TYPE_ID 1 GARD
IS_ACTIVE true GARD
IS_RARE true GARD
IS_SPANISH false GARD
MDA 19880608 MSH
MESH_DEFINITION A type of glomerulonephritis that is characterized by the accumulation of immune deposits (COMPLEMENT MEMBRANE ATTACK COMPLEX) on the outer aspect of the GLOMERULAR BASEMENT MEMBRANE. It progresses from subepithelial dense deposits, to basement membrane reaction and eventual thickening of the basement membrane. NDFRT
MESH_DUI D015433 NDFRT
MESH_NAME Glomerulonephritis, Membranous NDFRT
MESH_UI M0023781 NDFRT
MMR 20060705 MSH
MN C12.777.419.570.363.625 MSH
MN C13.351.968.419.570.363.625 MSH
MN C20.111.535 MSH
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Membranous Nephropathy NCI
NUI N0000003237 NDFRT
ORDER_NO 23237 ICD10CM
PM 1989; for HEYMANN NEPHRITIS see GLOMERULONEPHRITIS 1987-2006 MSH
PRIMARY_PATH 10018372$10018365$10029149$10038359$Glomerulonephritis membranous$Glomerulonephritis and nephrotic syndrome$Nephropathies$Renal and urinary disorders MDR
PRIMARY_SOC 10038359 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/9180/membranous-nephropathy/resources/1 GARD
RXAUI 3156437 RXNORM
RXAUI 3165695 RXNORM
RXAUI 3165696 RXNORM
RXAUI 3197414 RXNORM
RXAUI 3197416 RXNORM
RXAUI 3197419 RXNORM
RXAUI 3205627 RXNORM
RXCUI 1022469 RXNORM
SMQ_TERM_ADDVERSION 16.0 MDR
SMQ_TERM_ADDVERSION 19.0 MDR
SMQ_TERM_ADDVERSION 9.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_CAT B MDR
SMQ_TERM_CAT F MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 16.0 MDR
SMQ_TERM_LMVERSION 19.0 MDR
SMQ_TERM_LMVERSION 9.0 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SMQ_TERM_WEIGHT 1 MDR
SNOMED_CID 77182004 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS N05.2 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~N05.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS N05.9 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~N05.9 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~K021. SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T045564 MSH
TERMUI T045565 MSH
TERMUI T045566 MSH
TERMUI T045567 MSH
TERMUI T045569 MSH
TERMUI T656822 MSH
TH NLM (1989) MSH
TH NLM (2007) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0017665

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