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Membranoproliferative Glomerulonephritis (CUI C0017662) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0017662

NCI Thesaurus Code: C34644  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: Inflammation of the glomeruli characterized by deposits at the intraglomerular mesangium, resulting in thickening of the glomerular basement membrane, activation of complement, and impaired kidney function secondary to damaged glomeruli.

HPO Definition: Proliferation of mesangial cells, increase in the mesangial extracellular matrix, and a thickening of the glomerular capillary walls. [Eurenomics:fschaefer, MeSH:D015432]

NICHD Definition: Proliferative glomerulonephritis characterized by mesangial hypercellularity, endocapillary proliferation and glomerular capillary wall remodeling.

MSH Definition: Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN.

Synonyms & Abbreviations: (see Synonym Details)
Chronic glomerulonephritis, lobular
Glomerulonephritides, Hypocomplementemic
Glomerulonephritides, Membranoproliferative
Glomerulonephritides, Mesangiocapillary
Glomerulonephritis membranoproliferative
GLOMERULONEPHRITIS, HYPOCOMPLEMENTEMIC, CHRONIC
Glomerulonephritis, Hypocomplementemic
Glomerulonephritis, Membranoproliferative [Disease/Finding]
GLOMERULONEPHRITIS, MEMBRANOPROLIFERATIVE
GLOMERULONEPHRITIS, MESANGIOCAPILLARY
Hypocomplementemic Glomerulonephritides
Hypocomplementemic Glomerulonephritis
Lobular glomerulonephritis
MCGN - Mesangiocapillary glomerulonephritis
MCGN
Membranoproliferative Glomerulonephritides
Membranoproliferative glomerulonephritis NOS
Membranoproliferative glomerulonephritis
Mesangiocapillary Glomerulonephritides
Mesangiocapillary glomerulonephritis (disorder)
Mesangiocapillary glomerulonephritis
MPGN - Membranoproliferative glomerulonephritis
MPGN
Primary membranoproliferative glomerulonephritis

External Source Codes: 
NCI Thesaurus Code C34644 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN do not confuse with GLOMERULONEPHRITIS, MEMBRANOUS; do not make diagnoses: use the term used by the author MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID K022. SNOMEDCT_US
DATE_CREATED 2014-01-21T00:01:00 GARD
DATE_LAST_MODIFIED 2014-01-21T00:01:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DISEASE_IDENTIFIER_ID 23074 GARD
DISEASE_IDENTIFIER_ID 23075 GARD
DISEASE_IDENTIFIER_ID 23076 GARD
DX 19890101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
HAS_GARD_PAGE true GARD
HN 89 MSH
IDENTIFIER_SOURCE Orp GARD
IDENTIFIER_TYPE_ID 1 GARD
IS_ACTIVE true GARD
IS_RARE true GARD
IS_SPANISH false GARD
LAST_REVIEW_ACTION Modified GARD
LAST_REVIEW_DATE 2014-01-21T00:00:00 GARD
MDA 19880608 MSH
MESH_DEFINITION Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN. NDFRT
MESH_DUI D015432 NDFRT
MESH_NAME Glomerulonephritis, Membranoproliferative NDFRT
MESH_UI M0023780 NDFRT
MMR 20130708 MSH
MN C12.777.419.570.363.615 MSH
MN C13.351.968.419.570.363.615 MSH
MN C20.425 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Membranoproliferative Glomerulonephritis NCI
NUI N0000003236 NDFRT
PM 89 MSH
PRIMARY_PATH 10018370$10018365$10029149$10038359$Glomerulonephritis membranoproliferative$Glomerulonephritis and nephrotic syndrome$Nephropathies$Renal and urinary disorders MDR
PRIMARY_SOC 10038359 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/11982/membranoproliferative-glomerulonephritis/resources/1 GARD
RXAUI 3165688 RXNORM
RXAUI 3165693 RXNORM
RXAUI 3165694 RXNORM
RXAUI 3165697 RXNORM
RXAUI 3195400 RXNORM
RXAUI 3197406 RXNORM
RXAUI 3197835 RXNORM
RXCUI 1025782 RXNORM
SMQ_TERM_ADDVERSION 16.0 MDR
SMQ_TERM_ADDVERSION 19.0 MDR
SMQ_TERM_ADDVERSION 9.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_CAT B MDR
SMQ_TERM_CAT F MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 16.0 MDR
SMQ_TERM_LMVERSION 19.0 MDR
SMQ_TERM_LMVERSION 9.0 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SMQ_TERM_WEIGHT 1 MDR
SNOMED_CID 80321008 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS N05.5 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~N05.5 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS N05.5 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~N05.5 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~K022. SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T045558 MSH
TERMUI T045559 MSH
TERMUI T045560 MSH
TERMUI T045561 MSH
TERMUI T045562 MSH
TERMUI T045563 MSH
TH NLM (1989) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0017662

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