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NCIm Version: 201808 (Browser Version 2.9, using LexEVS 6.5.1)
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Foam Cell (CUI C0016390) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0016390

NCI Thesaurus Code: C12560  (see NCI Thesaurus info)

Semantic Type: Cell

NCIt Definition: A type of macrophage that ingests low-density lipoproteins found in fatty deposits on blood vessel walls, resulting in a foamy appearance.

HPO Definition: The presence of foam cells, which cells in an atheroma that can be derived from either macrophages or smooth muscle cells that have taken up modified low density lipoprotein particles and thereby take on a foamy appearance. [HPO:probinson]

FMA Definition: Macrophage located in wall of blood vessel and which contains lipid.

MSH Definition: Lipid-laden macrophages originating from monocytes or from smooth muscle cells.

Synonyms & Abbreviations: (see Synonym Details)
Cell, Foam
Cells, Foam
Foam cell (cell)
Foam cells
foam cell
Foamy Macrophage
Presence of foam cells

External Source Codes: 
NCI Thesaurus Code C12560 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN "lipid-laden macrophages"; A 11 qualif MSH
AQL CH CL CY DE EN IM ME MI PA PH PS RE SE TR UL VI MSH
AUTHORITY Open Biological Ontologies FMA
AUTHORITY Stedman's Electronic Medical Dictionary FMA
AUTHORITY Unified Medical Language System FMA
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CTV3ID XU8No SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 0432-6461 CSP
DX 19910101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
HN 91(77); was see under MACROPHAGES 1977-90 MSH
HPO_COMMENT Foam cells may contain polymorphic cytoplasmic inclusions consisting of lamellar osmiophilic membranes on electron microscopy. HPO
MDA 19760416 MSH
MMR 20070709 MSH
MN A11.329.372.368 MSH
MN A11.627.482.368 MSH
MN A11.733.397.368 MSH
MN A15.382.680.397.368 MSH
MN A15.382.812.522.368 MSH
PM 91; was see under MACROPHAGES 1977-90 MSH
SID HP:0003650 HPO
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU8No SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T016700 MSH
TH NLM (1977) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0016390

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