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Fibromyalgia (CUI C0016053) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0016053

NCI Thesaurus Code: C87497  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A chronic disorder of unknown etiology characterized by pain, stiffness, and tenderness in the muscles of neck, shoulders, back, hips, arms, and legs. Other signs and symptoms include headaches, fatigue, sleep disturbances, and painful menstruation.

RADLEX Definition: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, headaches, and occasionally depression. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (fatigue syndrome, chronic). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95) [MeSH]

MEDLINEPLUS Definition: 

Fibromyalgia is a disorder that causes muscle pain and fatigue. People with fibromyalgia have "tender points" on the body. Tender points are specific places on the neck, shoulders, back, hips, arms, and legs. These points hurt when pressure is put on them.

People with fibromyalgia may also have other symptoms, such as

  • Trouble sleeping
  • Morning stiffness
  • Headaches
  • Painful menstrual periods
  • Tingling or numbness in hands and feet
  • Problems with thinking and memory (sometimes called "fibro fog")

No one knows what causes fibromyalgia. Anyone can get it, but it is most common in middle-aged women. People with rheumatoid arthritis and other autoimmune diseases are particularly likely to develop fibromyalgia. There is no cure for fibromyalgia, but medicine can help you manage your symptoms. Getting enough sleep, exercising, and eating well may also help.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

NICHD Definition: Chronic, diffuse, non-inflammatory musculoskeletal pain disorder with characteristic tender points of neck, back, shoulders, hips, arms and legs, and associated with fatigue and sleep disturbance. Other symptoms may include headaches, abdominal discomfort, and depression/anxiety. It may also be associated with a primary rheumatic disorder.

CSP Definition: an acute, subacute, or chronic painful state of muscles, subcutaneous tissues, ligaments, tendons, or fasciae caused by a number of agents such as trauma, strain, occupation, exposure, posture, infection, or arthritis.

MSH Definition: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)

Synonyms & Abbreviations: (see Synonym Details)
Diffuse Myofascial Pain Syndrome
Fibromyalgia (disorder)
Fibromyalgia [Disease/Finding]
Fibromyalgia Fibromyositis Syndrome
Fibromyalgia syndrome
Fibromyalgia-Fibromyositis Syndromes
Fibromyalgia-Fibromyositis Syndrome
Fibromyalgias
FIBROMYALGIA
Fibromyalgie
fibromyositis fibromyalgia syndrome
Fibromyositis-Fibromyalgia Syndromes
Fibromyositis-Fibromyalgia Syndrome
Fibromyositis
Fibrositides
Fibrositis (disorder)
FIBROSITIS
FMS
MPD syndrome
MPS - myofascial pain syndrome
Muscular rheumatism (disorder)
muscular rheumatism
myofascial pain dysfunction syndrome
Myofascial pain syndrome (disorder)
Myofascial Pain Syndrome, Diffuse
Myofascial pain syndrome
Myofascial trigger point syndrome
Rheumatism, Muscular
RHEUMATISM, TENSION
Syndrome, Fibromyalgia-Fibromyositis
Syndrome, Fibromyositis-Fibromyalgia
Syndromes, Fibromyalgia-Fibromyositis
Syndromes, Fibromyositis-Fibromyalgia

External Source Codes: 
NCI Thesaurus Code C87497 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID N239. SNOMEDCT_US
CTV3ID N2402 SNOMEDCT_US
CTV3ID XUGc6 SNOMEDCT_US
CTV3ID XUwlm SNOMEDCT_US
DATE_CREATED 10/22/1998 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 0729-8307 CSP
DID 2139-2181 CSP
DX 19890101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20160131 SNOMEDCT_US
EFFECTIVE_TIME 20170731 SNOMEDCT_US
FX D015673 MSH
HN 89; was FIBROSITIS 1963-88 MSH
IAN DEFAULT ICD10
INCLUSION_TERM Fibromyositis ICD10
INCLUSION_TERM Fibrositis ICD10
INCLUSION_TERM Myofibrositis ICD10
MDA 19990101 MSH
MESH_DEFINITION A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95) NDFRT
MESH_DUI D005356 NDFRT
MESH_NAME Fibromyalgia NDFRT
MESH_UI M0008454 NDFRT
MMR 19991103 MSH
MN C05.651.324 MSH
MN C05.799.321 MSH
MN C10.668.491.425 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/fibromyalgia.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/fibromyalgia.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Arthritis and Musculoskeletal and Skin Diseases http://www.niams.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Fibromyalgia NCI
NUI N0000001250 NDFRT
OL use FIBROMYALGIA to search FIBROSITIS 1966-88 MSH
ORDER_NO 20120 ICD10CM
PM 89; was FIBROSITIS 1963-88 MSH
PRIMARY_PATH 10048439$10028323$10028302$10028395$Fibromyalgia$Muscle pains$Muscle disorders$Musculoskeletal and connective tissue disorders MDR
PRIMARY_SOC 10028395 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3146840 RXNORM
RXAUI 3160591 RXNORM
RXAUI 3160593 RXNORM
RXAUI 3160596 RXNORM
RXAUI 3160604 RXNORM
RXAUI 3160643 RXNORM
RXAUI 3200891 RXNORM
RXAUI 3232165 RXNORM
RXCUI 1022590 RXNORM
SMQ_TERM_ADDVERSION 20.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 20.0 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 203101004 NDFRT
SNOMED_CID 203102006 NDFRT
SNOMED_CID 24693007 NDFRT
SNOMED_CID 56557000 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS M79.19 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS M79.79 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~M79.19 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~M79.79 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS M79.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS M79.7 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF CERVICAL TRIGGER POINT SYNDROME CHOOSE M54.2 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF FIBROSITIS AND NODULAR FASCIITIS CHOOSE M72.4 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF LUMBAR TRIGGER POINT SYNDROME CHOOSE M54.5 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF THORACIC TRIGGER POINT SYNDROME CHOOSE M54.6 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 240044003 | Fibrositis and nodular fasciitis | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 279030006 | Cervical trigger point syndrome | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 279036000 | Thoracic trigger point syndrome | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 279041008 | Lumbar trigger point syndrome | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~M54.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~M54.5 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~M54.6 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~M72.4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~M79.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~M79.7 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~N239. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~N2402 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUGc6 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUwlm SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T016350 MSH
TERMUI T016351 MSH
TERMUI T016352 MSH
TERMUI T369282 MSH
TERMUI T369283 MSH
TERMUI T369284 MSH
TERMUI T369285 MSH
TH NLM (1966) MSH
TH NLM (2000) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0016053

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