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Epilepsy (CUI C0014544) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0014544

NCI Thesaurus Code: C3020  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions.

MEDLINEPLUS Definition: 

Epilepsy is a brain disorder that causes people to have recurring seizures. The seizures happen when clusters of nerve cells, or neurons, in the brain send out the wrong signals. People may have strange sensations and emotions or behave strangely. They may have violent muscle spasms or lose consciousness.

Epilepsy has many possible causes, including illness, brain injury, and abnormal brain development. In many cases, the cause is unknown.

Doctors use brain scans and other tests to diagnose epilepsy. It is important to start treatment right away. There is no cure for epilepsy, but medicines can control seizures for most people. When medicines are not working well, surgery or implanted devices such as vagus nerve stimulators may help. Special diets can help some children with epilepsy.

NIH: National Institute of Neurological Disorders and Stroke

NCI-GLOSS Definition: A group of disorders marked by problems in the normal functioning of the brain. These problems can produce seizures, unusual body movements, a loss of consciousness or changes in consciousness, as well as mental problems or problems with the senses.

NICHD Definition: A neurological disorder characterized by recurring seizures.

SNOMEDCT_US Definition: A disorder characterized by recurrent seizures

CSP Definition: brain disorder characterized by recurring excessive neuronal discharge, exhibited by transient episodes of motor, sensory, or psychic dysfunction, with or without unconsciousness or convulsive movements.

MSH Definition: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Synonyms & Abbreviations: (see Synonym Details)
EP - Epilepsy
epilepsia
Epilepsies
Epilepsy (disorder)
Epilepsy [Disease/Finding]
Epilepsy all types
Epilepsy NOS
Epilepsy, unspecified
epilepsy
Epileptic attack
Epileptic convulsions NOS
Epileptic convulsion
Epileptic disorder
Epileptic fits NOS
Epileptic fit
Epileptic seizure (finding)
Epileptic seizures NOS
Epileptic Seizures
epileptic seizure
Epileptic
Seizure disorder (disorder)
Seizure disorder NOS
Seizure Disorders
SEIZURE DISORDER
SEIZURE DIS
Seizure, Epileptic
Seizures, Epileptic

External Source Codes: 
NCI Thesaurus Code C3020 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN GEN or unspecified; prefer specifics MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID F25.. SNOMEDCT_US
CTV3ID XaEIj SNOMEDCT_US
CTV3ID XU7DQ SNOMEDCT_US
DATE_CREATED 08/04/1999 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 0485-6986 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20050131 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
FX D012640 MSH
IAN DEFAULT ICD10
ICE Epileptic convulsions, fits, or seizures NOS; Seizure disorder NOS ICD9CM
INCLUSION_TERM Epileptic: convulsions NOS ICD10
INCLUSION_TERM Epileptic: fits NOS ICD10
INCLUSION_TERM Epileptic: seizures NOS ICD10
IPX -G40 ICPC
IPX -G41 ICPC
MDA 19990101 MSH
MESH_DEFINITION A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313) NDFRT
MESH_DUI D004827 NDFRT
MESH_NAME Epilepsy NDFRT
MESH_UI M0007564 NDFRT
MMR 20040707 MSH
MN C10.228.140.490 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/epilepsy.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/epilepsy.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Neurological Disorders and Stroke http://www.ninds.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Epilepsy NCI
NUI N0000001126 NDFRT
ORDER_NO 05981 ICD10CM
PRIMARY_PATH 10015037$10039912$10039911$10029205$Epilepsy$Seizures and seizure disorders NEC$Seizures (incl subtypes)$Nervous system disorders MDR
PRIMARY_SOC 10029205 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3154828 RXNORM
RXAUI 3154829 RXNORM
RXAUI 3154950 RXNORM
RXAUI 3237186 RXNORM
RXAUI 3237275 RXNORM
RXCUI 1021750 RXNORM
SMQ_TERM_ADDVERSION 10.0 MDR
SMQ_TERM_ADDVERSION 15.1 MDR
SMQ_TERM_ADDVERSION 9.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_CAT G MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 10.0 MDR
SMQ_TERM_LMVERSION 15.1 MDR
SMQ_TERM_LMVERSION 9.0 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SMQ_TERM_WEIGHT 2 MDR
SNOMED_CID 128613002 NDFRT
SNOMED_CID 84757009 NDFRT
SOS A condition characterized by recurrent electroencephalographic seizures of various types that are associated with a disturbance of consciousness. AOD
SOS Excludes: convulsion (convulsive) disorder (780.39); convulsive seizures or fit NOS (780.39); recurrent convulsions (780.39) ICD9CM
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS G40.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS R56.8 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~G40.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~R56.8 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS G40.909 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS G40.909 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS R56.9 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF AGE AT ONSET OF CLINICAL FINDING BEFORE 29.0 DAYS CHOOSE P90 | DESCENDANTS NOT EXHAUSTIVELY MAPPED | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF ANOXIC EPILEPTIC SEIZURE CHOOSE G40.802 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF ANOXIC EPILEPTIC SEIZURE CHOOSE R09.02 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF EPILEPTIC SEIZURES - AKINETIC CHOOSE G40.409 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF EPILEPTIC SEIZURES - ATONIC CHOOSE G40.409 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF EPILEPTIC SEIZURES - CLONIC CHOOSE G40.409 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF EPILEPTIC SEIZURES - TONIC CHOOSE G40.409 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF SINGLE EPILEPTIC SEIZURE CHOOSE G40.409 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF WITNESSED EPILEPTIC SEIZURE CHOOSE G40.409 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~5 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~6 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~7 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~8 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 192981006 | Epileptic seizures - atonic | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 192982004 | Epileptic seizures - akinetic | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 192991000 | Epileptic seizures - clonic | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 192993002 | Epileptic seizures - tonic | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 438156004 | Anoxic epileptic seizure | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 445095002 | Witnessed epileptic seizure | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 445518008 | Age at onset of clinical finding (observable entity) | < 29.0 days SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 981000119108 | Single epileptic seizure | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G40.409 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G40.802 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G40.909 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~P90 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~R09.02 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~R56.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~F25.. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XaEIj SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU7DQ SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T014710 MSH
TERMUI T014711 MSH
TERMUI T014712 MSH
TERMUI T367712 MSH
TH BIOETHICS (1991) MSH
TH NLM (1998) MSH
TH NLM (2000) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0014544

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