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Endometriosis (CUI C0014175) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0014175

NCI Thesaurus Code: C3014  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs.

RADLEX Definition: A condition in which functional endometrial tissue is present outside the uterus. It is often confined to the pelvis involving the ovary, the ligaments, cul-de-sac, and the uterovesical peritoneum. [MeSH]

HPO Definition: The growth of endometrial tissue outside the uterus. [HPO:probinson, pmid:25221341]

MEDLINEPLUS Definition: 

Endometriosis is a problem affecting a woman's uterus - the place where a baby grows when she's pregnant. Endometriosis is when the kind of tissue that normally lines the uterus grows somewhere else. It can grow on the ovaries, behind the uterus or on the bowels or bladder. Rarely, it grows in other parts of the body.

This "misplaced" tissue can cause pain, infertility, and very heavy periods. The pain is usually in the abdomen, lower back or pelvic areas. Some women have no symptoms at all. Having trouble getting pregnant may be the first sign.

The cause of endometriosis is not known. Pain medicines and hormones often help. Severe cases may need surgery. There are also treatments to improve fertility in women with endometriosis.

NCI-GLOSS Definition: A benign condition in which tissue that looks like endometrial tissue grows in abnormal places in the abdomen.

CSP Definition: condition in which tissue more or less perfectly resembling the uterine mucous membrane (the endometrium) and containing typical endometrial granular and stromal elements occurs aberrantly in various locations in the pelvic cavity.

MSH Definition: A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum.

Synonyms & Abbreviations: (see Synonym Details)
Endometrioses
Endometriose
Endometriosis (clinical)
Endometriosis (disorder)
Endometriosis (morphologic abnormality)
Endometriosis [Disease/Finding]
Endometriosis NOS
Endometriosis, site unspecified
Endometriosis, unspecified
Endometriosis
Endo

External Source Codes: 
NCI Thesaurus Code C3014 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN non-neoplastic & nothing to do with "endometrial carcinoma" ( = ENDOMETRIAL NEOPLASMS); coord IM with specific precoord organ/dis term (IM) MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CTV3ID XU7L9 SNOMEDCT_US
CTV3ID XUY03 SNOMEDCT_US
DATE_CREATED 06/21/1999 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2000-5488 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20030731 SNOMEDCT_US
EFFECTIVE_TIME 20170131 SNOMEDCT_US
HPO_COMMENT The main manifestations of endometriosis are chronic upper abdominal pain and infertility. Endometriosis occurs primarily on the pelvic peritoneum, ovaries, and rectovaginal septum, and in rare cases on the diaphragm, pleura, and pericardium. Endometriosis affects 6 to 10% of women of reproductive age, 50 to 60% of women and teenage girls with pelvic pain, and up to 50% of women with infertility. Peritoneal disease, which is dependent on estrogen for growth, derives from retrograde menstruation of steroid hormone sensitive endometrial cells and tissues, which implant on peritoneal surfaces and elicit an inflammatory response. This response is accompanied by angiogenesis, adhesions, fibrosis, scarring, neuronal infiltration, and anatomical distortion resulting in pain and infertility. HPO
IAN DEFAULT ICD10
MDA 19990101 MSH
MESH_DEFINITION A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum. NDFRT
MESH_DUI D004715 NDFRT
MESH_NAME Endometriosis NDFRT
MESH_UI M0007413 NDFRT
MMR 20120703 MSH
MN C13.351.500.163 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MODULE_ID 731000124108 SNOMEDCT_US
MODULE_NAME US National Library of Medicine maintained module SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/endometriosis.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Arabic https://www.nlm.nih.gov/medlineplus/languages/endometriosis.html#Arabic MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/endometriosis.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Child Health and Human Development http://www.nichd.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NUI N0000001102 NDFRT
ORDER_NO 23732 ICD10CM
ORDER_NO 23741 ICD10CM
PRIMARY_PATH 10014778$10013376$10046828$10038604$Endometriosis$Uterine disorders NEC$Uterine, pelvic and broad ligament disorders$Reproductive system and breast disorders MDR
PRIMARY_SOC 10038604 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3154070 RXNORM
RXAUI 3154071 RXNORM
RXCUI 1024249 RXNORM
SID HP:0030013 HPO
SNOMED_CID 129103003 NDFRT
SNOMEDID D7-70089 SNOMEDCT_US
SNOMEDID M-76002 SNOMEDCT_US
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS N80.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~N80.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS N80.9 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~N80.9 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU7L9 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUY03 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~D7-70089 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~M-76002 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T014432 MSH
TH NLM (1966) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0014175

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