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Encephalitis (CUI C0014038) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0014038

NCI Thesaurus Code: C26760  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: An inflammatory process affecting the brain parenchyma. Causes include viral infections and less frequently bacterial infections, toxins, and immune-mediated processes.

RADLEX Definition: Inflammation of the brain due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see encephalitis, viral) are a relatively frequent cause of this condition. [MeSH]

MEDLINEPLUS Definition: 

Encephalitis is an inflammation of the brain. Usually the cause is a viral infection, but bacteria can also cause it. It can be mild or severe. Most cases are mild. You may have flu-like symptoms. With a mild case, you may just need rest, plenty of fluids, and a pain reliever.

Severe cases need immediate treatment. Symptoms of severe cases include

  • Severe headache
  • Sudden fever
  • Drowsiness
  • Vomiting
  • Confusion
  • Seizures

In babies, additional symptoms may include constant crying, poor feeding, body stiffness, and bulging in the soft spots of the skull.

Severe cases may require a stay in the hospital. Treatments include oral and intravenous medicines to reduce inflammation and treat infection. Patients with breathing difficulties may need artificial respiration. Some people may need physical, speech, and occupational therapy once the illness is under control.

NIH: National Institute of Neurological Disorders and Stroke

NICHD Definition: Inflammation of the brain.

CSP Definition: inflammation of the brain due to infection, autoimmune processes, toxins, and other conditions; viral infections are a relatively frequent cause of this condition.

MSH Definition: Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.

Synonyms & Abbreviations: (see Synonym Details)
Brain Inflammations
Brain inflammation
BRAIN INFLAMM
Encephalitis (disorder)
Encephalitis [Disease/Finding]
Encephalitis NOS
encephalitis
ENCEPH
Enzephalitis
INFLAMM BRAIN
Inflammation, Brain

External Source Codes: 
NCI Thesaurus Code C26760 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN general, note specifics particularly INFECTIOUS ENCEPHALITIS and ENCEPHALITIS, VIRAL MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source FDA NCI
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID X000h SNOMEDCT_US
DATE_CREATED 07/13/1999 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 2042-4877 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FDA_Table Patient Code (Appendix B) NCI
FX D004679 MSH
MDA 19990101 MSH
MESH_DEFINITION Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition. NDFRT
MESH_DUI D004660 NDFRT
MESH_NAME Encephalitis NDFRT
MESH_UI M0007337 NDFRT
MMR 20160226 MSH
MN C10.228.140.430 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/encephalitis.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/encephalitis.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Neurological Disorders and Stroke http://www.ninds.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Encephalitis NCI
NUI N0000001076 NDFRT
PRIMARY_PATH 10014581$10007935$10021879$10021881$Encephalitis$Central nervous system and spinal infections$Infections - pathogen unspecified$Infections and infestations MDR
PRIMARY_SOC 10021881 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
REF orcid.org/0000-0001-5208-3432 HPO
RXAUI 3118703 RXNORM
RXAUI 3153680 RXNORM
RXAUI 3153686 RXNORM
RXAUI 3181028 RXNORM
RXCUI 1022474 RXNORM
SMQ_TERM_ADDVERSION 10.1 MDR
SMQ_TERM_ADDVERSION 18.0 MDR
SMQ_TERM_ADDVERSION 19.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_CAT B MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 10.1 MDR
SMQ_TERM_LMVERSION 18.0 MDR
SMQ_TERM_LMVERSION 19.0 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 45170000 NDFRT
SNOMEDID DA-10100 SNOMEDCT_US
SOS Inflammation of the CNS caused by infection. AOD
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS G04.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~G04.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS G04.90 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G04.90 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X000h SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~DA-10100 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T014244 MSH
TERMUI T367439 MSH
TERMUI T367441 MSH
TH NLM (2000) MSH
TH POPLINE (1994) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0014038

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