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Edetic Acid (CUI C0013618) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0013618

NCI Thesaurus Code: C61742  (see NCI Thesaurus info)

Semantic Type: Indicator, Reagent, or Diagnostic Aid

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

NCIt Definition: The acid form of edetate, a chelating agent with anti-hypercalcemic and anticoagulant properties. Edetic acid binds calcium and heavy metal ions, forming soluble stable complexes which are readily excreted by the kidneys. This results in a decrease in serum calcium levels. This agent is also used as an anticoagulant for blood specimens and is applied as a treatment of lead poisoning.

MSH Definition: A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.

CSP Definition: chelating agent that binds calcium and heavy metal ions; used as an anticoagulant for blood specimens and for treatment of lead poisoning and hypercalcemia.

Synonyms & Abbreviations: (see Synonym Details)
(ethylenedinitrilo)tetraacetic acid, ion(4-)
Acid, Edetic
Acid, Ethylenediaminetetraacetic
Acid, Ethylenedinitrilotetraacetic
acide edetique
Acide ethylenediaminetetracetique
Acido edetico
Acidum edeticum
Edathamil
Edetic Acid [Chemical/Ingredient]
Edetic Acid
EDTA, ion(4-)
EDTA
Ethylenediamine tetra-acetate (substance)
Ethylenediamine tetra-acetate
ethylenediaminetetraacetate
Ethylenediaminetetraacetic acid
Ethylenedinitrilotetraacetic Acid
Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl))-
N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine)
N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine)
{[-(bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid

External Source Codes: 
NCI Thesaurus Code C61742 (see NCI Thesaurus info)
CAS Registry Number 60-00-4 (see NLM ChemIDplus info)
FDA UNII Code 9G34HU7RV0

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHEBI_ID CHEBI:42191 NCI
Chemical_Formula C10H16N2O8 NCI
Contributing_Source FDA NCI
CTV3ID XUJAJ SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 0124-2508 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FDA_UNII_CODE 9G34HU7RV0 DRUGBANK
FDA_UNII_CODE 9G34HU7RV0 NDFRT
HN 92(63) MSH
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive. NDFRT
MESH_DUI D004492 NDFRT
MESH_NAME Edetic Acid NDFRT
MESH_UI M0007067 NDFRT
MMR 20140616 MSH
MN D02.092.782.258.368.250 MSH
MN D02.241.081.018.253 MSH
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006192 NDFRT
NUI N0000145867 NDFRT
PA D000925 MSH
PA D005503 MSH
PA D065096 MSH
PM 92; see EDTA 1966-91, see EDATHAMIL 1963-65 MSH
RN 9G34HU7RV0 MSH
RR 139-33-3 (di-Na salt) MSH
RR 14667-04-0 (Mg salt) MSH
RR 17421-79-3 (mono-Na salt) MSH
RR 2001-94-7 (di-K salt) MSH
RR 24267-45-6 (di-Na, mono-K salt) MSH
RR 24669-13-4 (Cr salt) MSH
RR 53404-51-6 (mono-K salt) MSH
RR 60-00-4 (Edetic Acid) MSH
RR 62-33-9 MSH
RR 6381-92-6 (di-Na salt, di-H2O) MSH
RR 7379-27-3 (K salt) MSH
RR 7379-28-4 (Na salt) MSH
RR 76353-66-7 (Ca,Na salt) MSH
RR 7785-82-2 (Ca salt) MSH
RR 7FLD91C86K MSH
RR NDT563S5VZ MSH
RXAUI 114809 RXNORM
RXAUI 2070691 RXNORM
RXAUI 3150012 RXNORM
RXAUI 3150013 RXNORM
RXAUI 3150014 RXNORM
RXAUI 3153219 RXNORM
RXAUI 3153262 RXNORM
RXAUI 3153263 RXNORM
RXAUI 3155977 RXNORM
RXAUI 3155978 RXNORM
RXAUI 3166307 RXNORM
RXAUI 3201312 RXNORM
RXAUI 4232705 RXNORM
RXAUI 4232816 RXNORM
RXAUI 5072979 RXNORM
RXAUI 6395355 RXNORM
RXCUI 1370600 RXNORM
RXCUI 3755 RXNORM
SID APRD01327 DRUGBANK
SNOMEDID C-21723 SNOMEDCT_US
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SPL_SET_ID c9d03a52-8696-4965-996b-67c057a4f578 MTHSPL
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SPL_SET_ID cb03d2b3-66ea-470b-ac86-378ac83107d8 MTHSPL
SPL_SET_ID cbbb4da1-8406-4958-bfb6-7bf5d879d2df MTHSPL
SPL_SET_ID cc2dbe89-a84a-4c8c-b192-8fbee867c74f MTHSPL
SPL_SET_ID ce2e68ab-0bd8-4d06-96c8-f4f69afa6cc9 MTHSPL
SPL_SET_ID ce3b375e-14fe-46d0-829e-ba850e191a42 MTHSPL
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SPL_SET_ID d02ace0b-7244-45d4-987f-eb569303a426 MTHSPL
SPL_SET_ID d03fa89f-c5bb-483a-b3e5-72044acece9a MTHSPL
SPL_SET_ID d07eb2cb-1e18-46dd-a11f-03a9e91f6841 MTHSPL
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SPL_SET_ID e556a452-90ff-4efe-be0c-9899e6956844 MTHSPL
SPL_SET_ID e584b064-f279-4bcb-aa2e-197155edda72 MTHSPL
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SPL_SET_ID e63d89d0-cb5b-49cb-8564-b91dfc76af85 MTHSPL
SPL_SET_ID e75cbce9-3791-4572-9359-8049d6ce9beb MTHSPL
SPL_SET_ID e7e8db77-1c0a-4313-9f53-24dca617a4db MTHSPL
SPL_SET_ID e9135aeb-b436-4601-b29f-1fe39e261a0a MTHSPL
SPL_SET_ID eb250e55-1c38-449d-9d94-db11e22c7746 MTHSPL
SPL_SET_ID ebab46ed-87aa-4448-bf69-72c4bb2e8db3 MTHSPL
SPL_SET_ID ed63df26-3879-46df-8e09-10be569b25be MTHSPL
SPL_SET_ID edb69317-e6a1-4f50-9aa9-77be367aa8c3 MTHSPL
SPL_SET_ID f2a27068-59d6-4113-bdc7-094fbfda7bdf MTHSPL
SPL_SET_ID f4664f65-c308-40a5-a6cf-a751c464f409 MTHSPL
SPL_SET_ID f5ca55b5-1c71-4b27-860c-ffb6414b9fb2 MTHSPL
SPL_SET_ID f73d7c29-8b3e-49c1-9b33-68b3ede7f347 MTHSPL
SPL_SET_ID f8059aa8-3dc5-4e09-81c8-90a8eaee26f0 MTHSPL
SPL_SET_ID f950d4eb-39b9-4ef7-b5f3-0cf45d4d6bc0 MTHSPL
SPL_SET_ID f9b7bf26-e83f-4923-af17-cb4fc5d87a2b MTHSPL
SPL_SET_ID fe3ee6db-5ddb-4e60-bb8b-4b34edecf246 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUJAJ SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~C-21723 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T013717 MSH
TERMUI T013718 MSH
TERMUI T013719 MSH
TERMUI T013722 MSH
TERMUI T013723 MSH
TERMUI T013724 MSH
TH BAN (19XX) MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH NLM (1992) MSH
TH NLM (1999) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^71^Active/Master NDFRT
VUID 4017479 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0013618

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