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Diabetic Nephropathy (CUI C0011881) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0011881

NCI Thesaurus Code: C84417  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: Progressive kidney disorder caused by vascular damage to the glomerular capillaries, in patients with diabetes mellitus. It is usually manifested with nephritic syndrome and glomerulosclerosis.

MEDLINEPLUS Definition: 

If you have diabetes, your blood glucose, or blood sugar, levels are too high. Over time, this can damage your kidneys. Your kidneys clean your blood. If they are damaged, waste and fluids build up in your blood instead of leaving your body.

Kidney damage from diabetes is called diabetic nephropathy. It begins long before you have symptoms. An early sign of it is small amounts of protein in your urine. A urine test can detect it. A blood test can also help determine how well your kidneys are working.

If the damage continues, your kidneys could fail. In fact, diabetes is the most common cause of kidney failure in the United States. People with kidney failure need either dialysis or a kidney transplant.

You can slow down kidney damage or keep it from getting worse. Controlling your blood sugar and blood pressure, taking your medicines and not eating too much protein can help.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

NICHD Definition: Nephropathy resulting from diabetes mellitus. It is usually associated with proteinuria and progressive glomerulosclerosis.

CSP Definition: kidney disease and resultant kidney function impairment due to the long standing effects of diabetes on the microvasculature (glomerulus) of the kidney; features include increased urine protein and declining kidney function.

MSH Definition: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.

Synonyms & Abbreviations: (see Synonym Details)
-- Diabetic Kidney Disease
Diabetes with renal manifestations
Diabetic Kidney Diseases
Diabetic Kidney Disease
Diabetic Kidney Problems
Diabetic Nephropathies [Disease/Finding]
Diabetic Nephropathies
Diabetic nephropathy NOS
DIABETIC NEPHROPATHY
Diabetic renal disease (disorder)
Diabetic renal disease
Kidney Disease, Diabetic
Kidney Diseases, Diabetic
Nephropathies, Diabetic
Nephropathy, Diabetic
Renal disorder associated with diabetes mellitus

External Source Codes: 
NCI Thesaurus Code C84417 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN coord IM with specific kidney dis (IM); do not confuse with DIABETES INSIPIDUS, NEPHROGENIC, a form of diabetes insipidus MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID X30Kk SNOMEDCT_US
DATE_CREATED 10/04/2001 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 0862-6260 CSP
DX 19650101 MSH
EFFECTIVE_TIME 20060731 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
HN 65(64); KIMMELSTIEL-WILSON SYNDROME was heading 1963-76 MSH
ICA Use additional code to identify manifestation, as: {diabetic: {nephropathy NOS (583.81); nephrosis (581.81)}; intercapillary glomerulosclerosis (581.81); Kimmelstiel-Wilson syndrome (581.81)}; chronic kidney disease (585.1-585.9) ICD9CM
MDA 19990101 MSH
MESH_DEFINITION KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE. NDFRT
MESH_DUI D003928 NDFRT
MESH_NAME Diabetic Nephropathies NDFRT
MESH_UI M0006160 NDFRT
MMR 20060705 MSH
MN C12.777.419.192 MSH
MN C13.351.968.419.192 MSH
MN C19.246.099.875 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/diabetickidneyproblems.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Arabic https://www.nlm.nih.gov/medlineplus/languages/diabetickidneyproblems.html#Arabic MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Russian https://www.nlm.nih.gov/medlineplus/languages/diabetickidneyproblems.html#Russian MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Somali https://www.nlm.nih.gov/medlineplus/languages/diabetickidneyproblems.html#Somali MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/diabetickidneyproblems.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Diabetes and Digestive and Kidney Diseases http://www.niddk.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Diabetic Nephropathy NCI
NUI N0000000957 NDFRT
OL use DIABETIC NEPHROPATHIES to search KIMMELSTIEL-WILSON SYNDROME 1966-76 MSH
PM 65; KIMMELSTIEL-WILSON SYNDROME was heading 1963-76 MSH
PRIMARY_PATH 10061835$10029150$10029149$10038359$Diabetic nephropathy$Nephropathies and tubular disorders NEC$Nephropathies$Renal and urinary disorders MDR
PRIMARY_SOC 10038359 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3146369 RXNORM
RXAUI 3146377 RXNORM
RXAUI 3146378 RXNORM
RXAUI 3146379 RXNORM
RXCUI 1021799 RXNORM
SMQ_TERM_ADDVERSION 16.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 16.0 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 127013003 NDFRT
SNOMED_CID 197605007 NDFRT
SNOMED_CID 21858001 NDFRT
SNOMED_CID 54181000 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS E14.2 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS N08.3 | THIS CODE MAY BE USED IN THE PRIMARY POSITION WHEN THE MANIFESTATION IS THE PRIMARY FOCUS OF CARE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~E14.2 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~N08.3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS E11.21 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E11.21 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X30Kk SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T011764 MSH
TERMUI T577498 MSH
TERMUI T592718 MSH
TH NLM (1964) MSH
TH NLM (2005) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

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