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Diabetic Ketoacidosis (CUI C0011880) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0011880

NCI Thesaurus Code: C50530  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.

HPO Definition: A type of diabetic metabolic abnormality with an accumulation of ketone bodies. [HPO:probinson]

NICHD Definition: A metabolic derangement characterized by ketosis, acidosis, and often hyperglycemia, as a consequence of absolute or relative insulin deficiency.

FDA Definition: A type of metabolic acidosis produced by accumulation of ketone bodies resulting from uncontrolled diabetes mellitus.

CSP Definition: complication of diabetes resulting from severe insulin deficiency coupled with an absolute or relative increase in glucagon concentration; metabolic acidosis is caused by the breakdown of adipose stores and resulting increased levels of free fatty acids; glucagon accelerates the oxidation of the free fatty acids producing excess ketone bodies (ketosis).

MSH Definition: A life-threatening complication of diabetes mellitus, primarily of TYPE 1 DIABETES MELLITUS with severe INSULIN deficiency and extreme HYPERGLYCEMIA. It is characterized by KETOSIS; DEHYDRATION; and depressed consciousness leading to COMA.

Synonyms & Abbreviations: (see Synonym Details)
Acidoses, Diabetic
ACIDOSIS DIABETIC
ACIDOSIS, DIABETIC
Diabetes Mellitus with Ketoacidosis
Diabetes with ketoacidosis
Diabetic Acidoses
diabetic acidosis
Diabetic Ketoacidoses
Diabetic Ketoacidosis [Disease/Finding]
diabetic ketoacidosis
Diabetic Ketoses
Diabetic ketosis
DKA - diabetic ketoacidosis
DKA
Ketoacidoses, Diabetic
Ketoacidosis (diabetic)
Ketoacidosis in diabetes mellitus (disorder)
Ketoacidosis in diabetes mellitus
KETOACIDOSIS, DIABETIC
Ketoses, Diabetic
Ketosis, Diabetic

External Source Codes: 
NCI Thesaurus Code C50530 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source FDA NCI
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID XUdz3 SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 0862-6200 CSP
DX 19920101 MSH
EFFECTIVE_TIME 20060731 SNOMEDCT_US
FDA_Table Patient Code (Appendix B) NCI
HN 92; KETOSIS, DIABETIC was heading 1975-91 (see under ACIDOSIS, DIABETIC 1975-90); ACIDOSIS, DIABETIC was heading 1966-91 MSH
HN Introduced 2000. AOD
ICE Diabetic: {acidosis without mention of coma; ketosis without mention of coma} ICD9CM
MDA 19910530 MSH
MESH_DEFINITION A life-threatening complication of diabetes mellitus, primarily of TYPE 1 DIABETES MELLITUS with severe INSULIN deficiency and extreme HYPERGLYCEMIA. It is characterized by KETOSIS; DEHYDRATION; and depressed consciousness leading to COMA. NDFRT
MESH_DUI D016883 NDFRT
MESH_NAME Diabetic Ketoacidosis NDFRT
MESH_UI M0025687 NDFRT
MMR 20100625 MSH
MN C18.452.076.176.652.500 MSH
MN C18.452.394.750.535 MSH
MN C19.246.099.812 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Diabetic Ketoacidosis NCI
NUI N0000003499 NDFRT
OL use DIABETIC KETOACIDOSIS to search KETOSIS, DIABETIC 1975-91 & ACIDOSIS, DIABETIC 1966-91 MSH
PM 92; KETOSIS, DIABETIC was heading 1975-91 (see under ACIDOSIS, DIABETIC 1975-90); ACIDOSIS, DIABETIC was heading 1966-91 MSH
PRIMARY_PATH 10012671$10012655$10012653$10027433$Diabetic ketoacidosis$Diabetic complications NEC$Diabetic complications$Metabolism and nutrition disorders MDR
PRIMARY_PATH 10012673$10012655$10012653$10027433$Diabetic ketosis$Diabetic complications NEC$Diabetic complications$Metabolism and nutrition disorders MDR
PRIMARY_SOC 10027433 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3105421 RXNORM
RXAUI 3146345 RXNORM
RXAUI 3146365 RXNORM
RXAUI 3146366 RXNORM
RXAUI 3146368 RXNORM
RXAUI 3184509 RXNORM
RXAUI 3184559 RXNORM
RXCUI 1022795 RXNORM
SID HP:0008253 HPO
SMQ_TERM_ADDVERSION 9.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 20.1 MDR
SMQ_TERM_LMVERSION 9.0 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 24927004 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS E14.1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~E14.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS E13.10 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF DIABETIC KETOACIDOSIS WITHOUT COMA CHOOSE E11.69 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF DIABETIC KETOACIDOSIS WITHOUT COMA CHOOSE E87.2 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF KETOACIDOSIS IN TYPE 1 DIABETES MELLITUS CHOOSE E10.10 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF KETOACIDOSIS IN TYPE 1 DIABETES MELLITUS CHOOSE E87.2 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF KETOACIDOSIS IN TYPE 2 DIABETES MELLITUS CHOOSE E11.10 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 111556005 | Diabetic ketoacidosis without coma | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 420270002 | Ketoacidosis in type 1 diabetes mellitus | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 421750000 | Ketoacidosis in type 2 diabetes mellitus | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E10.10 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E11.10 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E11.69 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E13.10 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E87.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUdz3 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T050538 MSH
TERMUI T050539 MSH
TERMUI T050540 MSH
TERMUI T050541 MSH
TERMUI T050542 MSH
TERMUI T050543 MSH
TH NLM (1992) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0011880

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