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Comatose (CUI C0009421) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0009421

NCI Thesaurus Code: C34497  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A state of profound unconsciousness associated with markedly depressed cerebral activity. Causes include central nervous system damage, intoxication, and metabolic abnormalities.

HPO Definition: Complete absence of wakefulness and content of conscience, which manifests itself as a lack of response to any kind of external stimuli. [HPO:probinson]

MEDLINEPLUS Definition: 

A coma is a deep state of unconsciousness. An individual in a coma is alive but unable to move or respond to his or her environment. Coma may occur as a complication of an underlying illness, or as a result of injuries, such as brain injury.

A coma rarely lasts more than 2 to 4 weeks. The outcome for coma depends on the cause, severity, and site of the damage. People may come out of a coma with physical, intellectual, and psychological problems. Some people may remain in a coma for years or even decades. For those people, the most common cause of death is infection, such as pneumonia.

NIH: National Institute of Neurological Disorders and Stroke

NCI-GLOSS Definition: A condition in which a patient is in a state of deep sleep and cannot be awakened. A coma may be caused by many things, including trauma, drugs, toxins, or certain diseases.

NICHD Definition: Prolonged unconsciousness.

CSP Definition: profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused; coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem.

MSH Definition: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.

Synonyms & Abbreviations: (see Synonym Details)
Coma (disorder)
COMA (NOS)
Coma [Disease/Finding]
Coma NOS
Coma, unspecified
Comas
Comatose
coma
exanimation
Unspecified coma

External Source Codes: 
NCI Thesaurus Code C34497 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN check MeSH for specific coma terms MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CODE_FIRST any associated: ICD10CM
CODE_FIRST fracture of skull (S02.-) ICD10CM
CODE_FIRST intracranial injury (S06.-) ICD10CM
Contributing_Source FDA NCI
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID XUUrC SNOMEDCT_US
DATE_CREATED 07/06/2010 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2056-8649 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020731 SNOMEDCT_US
FDA_Table Patient Code (Appendix B) NCI
FX D002389 MSH
FX D018458 MSH
HPO_COMMENT Coma is generally a result of diffuse or extensive involvement of both hemispheres of the brain or lesions in the brainstem. HPO
IAN DEFAULT ICD10
INCLUSION_TERM Unconsciousness NOS ICD10
IPX R40 ICPC
MDA 19990101 MSH
MESH_DEFINITION A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION. NDFRT
MESH_DUI D003128 NDFRT
MESH_NAME Coma NDFRT
MESH_UI M0004841 NDFRT
MMR 20130709 MSH
MN C10.597.606.358.800.200 MSH
MN C23.888.592.604.359.800.200 MSH
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/coma.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/coma.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Neurological Disorders and Stroke http://www.ninds.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Coma NCI
NUI N0000000819 NDFRT
ORDER_NO 28553 ICD10CM
ORDER_NO 28554 ICD10CM
PRIMARY_PATH 10010071$10052770$10029305$10029205$Coma$Coma states$Neurological disorders NEC$Nervous system disorders MDR
PRIMARY_SOC 10029205 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3134578 RXNORM
RXAUI 3134582 RXNORM
RXAUI 3134606 RXNORM
RXCUI 988251 RXNORM
SMQ_TERM_ADDVERSION 10.1 MDR
SMQ_TERM_ADDVERSION 19.0 MDR
SMQ_TERM_ADDVERSION 9.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_CAT D MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 10.1 MDR
SMQ_TERM_LMVERSION 19.0 MDR
SMQ_TERM_LMVERSION 9.0 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 371632003 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS R40.2 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~R40.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS R40.20 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF AGE AT ONSET OF CLINICAL FINDING BEFORE 29.0 DAYS CHOOSE P91.5 | DESCENDANTS NOT EXHAUSTIVELY MAPPED | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 445518008 | Age at onset of clinical finding (observable entity) | < 29.0 days SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~P91.5 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~R40.20 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUUrC SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T009113 MSH
TERMUI T372627 MSH
TH BIOETHICS (1989) MSH
TH NLM (2000) MSH
TH ORD (2010) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0009421

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