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Coccidioidomycosis (CUI C0009186) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0009186

NCI Thesaurus Code: C84642  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A fungal infection caused by Coccidioides immitis. Affected individuals usually have mild flu-like symptoms. However, pneumonia and systemic involvement with the formation of abscesses may develop as complications of the disease.

MEDLINEPLUS Definition: 

Valley Fever is a disease caused by a fungus (or mold) called Coccidioides. The fungi live in the soil of dry areas like the southwestern U.S. You get it from inhaling the spores of the fungus. The infection cannot spread from person to person.

Anyone can get Valley Fever. But it's most common among older adults, especially those 60 and older. People who have recently moved to an area where it occurs are at highest risk for infection. Other people at higher risk include

  • Workers in jobs that expose them to soil dust. These include construction workers, agricultural workers, and military forces doing field training.
  • African Americans and Asians
  • Women in their third trimester of pregnancy
  • People with weak immune systems

Valley Fever is often mild, with no symptoms. If you have symptoms, they may include a flu-like illness, with fever, cough, headache, rash, and muscle aches. Most people get better within several weeks or months. A small number of people may develop a chronic lung or widespread infection.

Valley Fever is diagnosed by testing your blood, other body fluids, or tissues. Many people with the acute infection get better without treatment. In some cases, doctors may prescribe antifungal drugs for acute infections. Severe infections require antifungal drugs.

Centers for Disease Control and Prevention

NICHD Definition: An infection that is caused by Coccidioides immitis, which typically manifests as a flu-like illness, although pneumonia and systemic infection can occur.

CSP Definition: infection with a fungus of the genus Coccidioides, species C. immitis; primary form is an acute, benign, self limited respiratory infection due to inhalation of spores and varying in severity; secondary form is a virulent, severe, chronic, progressive granulomatous disease with systemic involvement.

MSH Definition: Infection with a fungus of the genus COCCIDIOIDES, endemic to the SOUTHWESTERN UNITED STATES. It is sometimes called valley fever but should not be confused with RIFT VALLEY FEVER. Infection is caused by inhalation of airborne, fungal particles known as arthroconidia, a form of FUNGAL SPORES. A primary form is an acute, benign, self-limited respiratory infection. A secondary form is a virulent, severe, chronic, progressive granulomatous disease with systemic involvement. It can be detected by use of COCCIDIOIDIN.

Synonyms & Abbreviations: (see Synonym Details)
Coccidioides immitis Infections
Coccidioides immitis infection
Coccidioidomycoses
Coccidioidomycosis (disorder)
Coccidioidomycosis [Disease/Finding]
Coccidioidomycosis infection
Coccidioidomycosis NOS
Coccidioidomycosis, unspecified
Coccidioidomycosis
desert fever
FEVER, DESERT
FEVER, SAN JOAQUIN
FEVER, VALLEY
Infection by Coccidioides immitis
Infection caused by Coccidioides immitis (disorder)
Infection caused by Coccidioides immitis
Infection, Coccidioides immitis
Infections, Coccidioides immitis
POSADAS-WERNICKE DISEASE
San Joaquin fever
San Joaquin Valley fever
Valley Fevers
Valley fever

External Source Codes: 
NCI Thesaurus Code C84642 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN fungus disease caused by COCCIDIOIDES, not COCCIDIA MSH
ANSWER_CODE 11900 LNC
ANSWER_CODE_SYSTEM NNDSS LNC
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH TM UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID XUHRz SNOMEDCT_US
CTV3ID XUiqy SNOMEDCT_US
DATE_CREATED 10/04/2010 MEDLINEPLUS
DATE_CREATED 2013-01-09T00:04:00 GARD
DATE_LAST_MODIFIED 2013-01-09T00:04:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 1988-4353 CSP
DISEASE_IDENTIFIER_ID 2410 GARD
DISEASE_IDENTIFIER_ID 2411 GARD
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20090731 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
HAS_GARD_PAGE true GARD
IAN DEFAULT ICD10
IDENTIFIER_TYPE_ID 1 GARD
IS_ACTIVE true GARD
IS_RARE true GARD
IS_SPANISH false GARD
LAST_REVIEW_ACTION Modified GARD
LAST_REVIEW_DATE 2013-07-16T00:00:00 GARD
MDA 19990101 MSH
MESH_DEFINITION Infection with a fungus of the genus COCCIDIOIDES, endemic to the SOUTHWESTERN UNITED STATES. It is sometimes called valley fever but should not be confused with RIFT VALLEY FEVER. Infection is caused by inhalation of airborne, fungal particles known as arthroconidia, a form of FUNGAL SPORES. A primary form is an acute, benign, self-limited respiratory infection. A secondary form is a virulent, severe, chronic, progressive granulomatous disease with systemic involvement. It can be detected by use of COCCIDIOIDIN. NDFRT
MESH_DUI D003047 NDFRT
MESH_NAME Coccidioidomycosis NDFRT
MESH_UI M0004676 NDFRT
MMR 20100625 MSH
MN C01.703.203 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/valleyfever.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/valleyfever.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Allergy and Infectious Diseases http://www.niaid.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Coccidioidomycosis NCI
NUI N0000000800 NDFRT
ORDER_NO 00936 ICD10CM
ORDER_NO 00946 ICD10CM
PRIMARY_PATH 10009825$10009824$10017528$10021881$Coccidioidomycosis$Coccidioides infections$Fungal infectious disorders$Infections and infestations MDR
PRIMARY_SOC 10021881 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/9525/coccidioidomycosis/resources/1 GARD
RXAUI 3134169 RXNORM
RXAUI 3134170 RXNORM
RXAUI 3605643 RXNORM
RXAUI 3606297 RXNORM
RXAUI 3606401 RXNORM
RXCUI 1023493 RXNORM
SNOMED_CID 60826002 NDFRT
SNOMEDID DE-40600 SNOMEDCT_US
SNOMEDID DE-40613 SNOMEDCT_US
SOS Includes: infection by Coccidioides (immitis); Posada-Wernicke disease ICD9CM
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS B38.8 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS B38.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~B38.8 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~B38.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS B38.9 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS B38.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF COCCIDIOIDAL MENINGITIS CHOOSE B38.4 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF COCCIDIOIDAL MENINGITIS CHOOSE G02 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 46303000 | Coccidioidal meningitis (disorder) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~B38.4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~B38.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G02 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUHRz SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUiqy SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~DE-40600 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~DE-40613 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T008829 MSH
TERMUI T764030 MSH
TERMUI T764031 MSH
TERMUI T764032 MSH
TH NLM (1966) MSH
TH NLM (2011) MSH
TH ORD (2010) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0009186

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