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Cluster Headache (CUI C0009088) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0009088

NCI Thesaurus Code: C117077  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A headache disorder that is characterized by periodic severe, unilateral orbital, supraorbital, and/or temporal pain, and is associated with ipsilateral cranial autonomic symptoms.

GARD Definition: Cluster headaches are a form of headache notable for their extreme pain and their pattern of occurring in "clusters", usually at the same time(s) of the day for several weeks.   A cluster headache usually begins suddenly with excruciating pain on one side of the head, often behind or around one eye.  In some individuals, it may be preceded by a migraine-like "aura." The pain usually peaks over the next 5 to 10 minutes, and then continues at that intensity for up to an hour or two before going away. Cluster headaches generally begin between the ages of 20 and 50, although the syndrome can also start in childhood or late in life. Males are much more likely than females to develop cluster headaches.   - this information is from GARD/ORDR/NCATS.

HPO Definition: A type of headache characterized by repeated attacks of unilateral pain lasting 15 to 180 minutes and associated with local autonomic signs. [HPO:probinson, pmid:21912573]

NICHD Definition: A headache disorder that is characterized by periodic severe, unilateral orbital, supraorbital, and/or temporal pain, and is associated with ipsilateral cranial autonomic symptoms.

MSH Definition: A primary headache disorder that is characterized by severe, strictly unilateral PAIN which is orbital, supraorbital, temporal or in any combination of these sites, lasting 15-180 min. occurring 1 to 8 times a day. The attacks are associated with one or more of the following, all of which are ipsilateral: conjunctival injection, lacrimation, nasal congestion, rhinorrhea, facial SWEATING, eyelid EDEMA, and miosis. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Synonyms & Abbreviations: (see Synonym Details)
BING-HORTON SYNDROME
CEPHALALGIA, HISTAMINE
CEPHALALGIA, PAROXYSMAL, NOCTURNAL, ORBITAL
Cephalgia, Histamine
Cephalgias, Histamine
Chronic cluster headache (disorder)
Chronic cluster headache NOS
Chronic Cluster Headaches
Chronic cluster headache
Ciliary neuralgia (disorder)
Ciliary Neuralgias
Ciliary neuralgia
Cluster Headache [Disease/Finding]
Cluster headache NOS
Cluster headache syn NOS
Cluster headache syndrome (disorder)
Cluster headache syndrome NOS
Cluster headache syndrome, unspecified
Cluster Headache Syndromes
Cluster headache syndrome
Cluster Headache, Chronic
Cluster Headaches, Chronic
CLUSTER HEADACHES
CLUSTER HEADACHE
ERYTHROPROSOPALGIA
HEADACHE HISTAMINE
Headache Syndrome, Cluster
Headache Syndromes, Cluster
HEADACHE VASOMOTOR
Headache, Chronic Cluster
Headache, Cluster
Headaches cluster
Headaches, Chronic Cluster
Headaches, Cluster
Histamine Cephalgias
Histamine cephalgia
HISTAMINE HEADACHE
HORTON SYNDROME
HORTON'S HEADACHE
Horton's neuralgia
Horton's Syndrome
Hortons Syndrome
Migraine, Neuralgic
Migraines, Neuralgic
Migrainous neuralgia
Neuralgia, Ciliary
Neuralgias, Ciliary
Neuralgic Migraines
Neuralgic Migraine
Syndrome, Cluster Headache
Syndrome, Horton's
Syndrome, Horton
Syndromes, Cluster Headache
Vasomotor headache

External Source Codes: 
NCI Thesaurus Code C117077 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
ANSWER_CODE 3 LNC
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID F2620 SNOMEDCT_US
CTV3ID X007X SNOMEDCT_US
CTV3ID XU1av SNOMEDCT_US
DATE_CREATED 2013-03-12T11:37:40Z HPO
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DX 19910101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
HAS_GARD_PAGE true GARD
HN 1991(1978) MSH
HPO_COMMENT According to the International Classification of Headache Disorders (ICHD-II), the diagnosis of cluster headache can be made with at least five attacks fulfilling criteria B-D:nB) Severe or very severe unilateral orbital, supraorbital and/or temporal pain lasting 15-180 minutes if untreated.nC) Headache is accompanied by at least 1 of the following:n(i) Ipsilateral conjunctival injection and/or lacrimation.n(ii) Ipsilateral nasal congestion and/or rhinorrhea.n(iii) Ipsilateral eyelid edema.n(iv) Ipsilateral forehead and facial sweating.n(v) Ipsilateral miosis and/or ptosis.n(vi) A sense of restlessness or agitation.nD) Attacks have a frequency from 1 every other day to 8/day.nAdditionally, the headaches cannot attributed to another disorder. HPO
IAN DEFAULT ICD10
ICE Ciliary neuralgia; Cluster headache NOS; Histamine cephalgia; lower half migraine; Migrainous neuralgia ICD9CM
INCLUSION_TERM Chronic paroxysmal hemicrania ICD10
INCLUSION_TERM Cluster headache: chronic ICD10
INCLUSION_TERM Cluster headache: episodic ICD10
IPX G44.0 ICPC
IS_RARE false GARD
IS_SPANISH false GARD
LAST_REVIEW_ACTION Modified GARD
MDA 19770513 MSH
MESH_DEFINITION A primary headache disorder that is characterized by severe, strictly unilateral PAIN which is orbital, supraorbital, temporal or in any combination of these sites, lasting 15-180 min. occurring 1 to 8 times a day. The attacks are associated with one or more of the following, all of which are ipsilateral: conjunctival injection, lacrimation, nasal congestion, rhinorrhea, facial SWEATING, eyelid EDEMA, and miosis. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1) NDFRT
MESH_DUI D003027 NDFRT
MESH_NAME Cluster Headache NDFRT
MESH_UI M0004652 NDFRT
MMR 20050630 MSH
MN C10.228.140.546.399.937.500 MSH
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Cluster Headache NCI
NUI N0000000798 NDFRT
ORDER_NO 06065 ICD10CM
ORDER_NO 06071 ICD10CM
PM 1991; see VASCULAR HEADACHE 1978-1990 MSH
PRIMARY_PATH 10059133$10019233$10019231$10029205$Cluster headache$Headaches NEC$Headaches$Nervous system disorders MDR
PRIMARY_SOC 10029205 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/10286/cluster-headache/resources/1 GARD
RXAUI 3133369 RXNORM
RXAUI 3133562 RXNORM
RXAUI 3133974 RXNORM
RXAUI 3133975 RXNORM
RXAUI 3133977 RXNORM
RXAUI 3171085 RXNORM
RXAUI 3173031 RXNORM
RXAUI 3173429 RXNORM
RXAUI 3173432 RXNORM
RXAUI 3205945 RXNORM
RXCUI 1022422 RXNORM
SNOMED_CID 193031009 NDFRT
SNOMED_CID 193947008 NDFRT
SNOMED_CID 230473009 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS G44.0 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~G44.0 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS G44.009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS G44.029 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF CHRONIC CLUSTER HEADACHE CHOOSE G44.029 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF EPISODIC CLUSTER HEADACHE CHOOSE G44.019 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INTRACTABLE EPISODIC CLUSTER HEADACHE CHOOSE G44.011 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 230472004 | Episodic cluster headache | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 230473009 | Chronic cluster headache | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 293901000119108 | Intractable episodic cluster headache | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G44.009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G44.011 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G44.019 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G44.029 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~F2620 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X007X SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU1av SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T008790 MSH
TERMUI T367192 MSH
TERMUI T367193 MSH
TERMUI T367194 MSH
TERMUI T367195 MSH
TERMUI T367196 MSH
TERMUI T367197 MSH
TERMUI T367198 MSH
TERMUI T367199 MSH
TH NLM (1978) MSH
TH NLM (2000) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

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