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Cholestasis (CUI C0008370) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0008370

NCI Thesaurus Code: C83006  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: Impairment of the bile flow caused by obstruction within the liver, or outside the liver in the bile duct system.

HPO Definition: Impairment of bile flow due to obstruction in bile ducts. [HPO:probinson]

NCI-GLOSS Definition: Any condition in which the release of bile from the liver is blocked. The blockage can occur in the liver (intrahepatic cholestasis) or in the bile ducts (extrahepatic cholestasis).

NICHD Definition: Diminished or obstructed bile flow.

CSP Definition: intrahepatic impairment of bile flow; usually due to liver cell damage, but may be due to obstruction of intrahepatic bile ducts.

CSP Definition: stoppage or suppression of bile by intrahepatic or extrahepatic causes.

MSH Definition: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).

Synonyms & Abbreviations: (see Synonym Details)
Bile duct obstruction NOS
Bile Duct Obstructions
bile duct obstruction
Bile duct occlusion
bile obstruction
bile occlusion
Bile stasis
Biliary Stases
BILIARY STASIS
Cholestases
Cholestasis (finding)
Cholestasis [Disease/Finding]
cholestasis
Duct Obstruction, Bile
Duct Obstructions, Bile
Obstruction of bile duct (disorder)
Obstruction of bile duct
Obstruction, Bile Duct
Obstructions, Bile Duct
Occlusion of bile duct (disorder)
Occlusion of bile duct
Stases, Biliary
Stasis, Biliary

External Source Codes: 
NCI Thesaurus Code C83006 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID J662. SNOMEDCT_US
CTV3ID J6620 SNOMEDCT_US
CTV3ID XUC19 SNOMEDCT_US
DATE_FIRST_PUBLISHED 2009-06-05 PDQ
DATE_LAST_MODIFIED 2009-06-05 PDQ
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 0413-4023 CSP
DID 4000-0147 CSP
DX 19720101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20040731 SNOMEDCT_US
EXCLUDES1 congenital obstruction of bile duct (Q44.3) ICD10CM
EXCLUDES1 obstruction of bile duct with cholelithiasis (K80.-) ICD10CM
FX D041781 MSH
HN 1972 (1969) MSH
HN ETOH descriptor 1995. AOD
IAN DEFAULT ICD10
ICE Occlusion of bile duct, except cystic duct, without mention of calculus; Stenosis of bile duct, except cystic duct, without mention of calculus; Stricture of bile duct, except cystic duct, without mention of calculus ICD9CM
INCLUSION_TERM Occlusion of bile duct without calculus ICD10
INCLUSION_TERM Stenosis of bile duct without calculus ICD10
INCLUSION_TERM Stricture of bile duct without calculus ICD10
MDA 19990101 MSH
MESH_DEFINITION Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS). NDFRT
MESH_DUI D002779 NDFRT
MESH_NAME Cholestasis NDFRT
MESH_UI M0004258 NDFRT
MMR 20030709 MSH
MN C06.130.120.135 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MSC Diagnosis.Term MTHMST
NCI_THESAURUS_CODE C83006 PDQ
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Cholestasis NCI
NUI N0000000762 NDFRT
ORDER_NO 13671 ICD10CM
ORIG_STY Secondary related condition PDQ
PM 1972 MSH
PRIMARY_PATH 10008635$10008636$10019654$10019805$Cholestasis$Cholestasis and jaundice$Hepatic and hepatobiliary disorders$Hepatobiliary disorders MDR
PRIMARY_PATH 10056375$10029976$10004606$10019805$Bile duct obstruction$Obstructive bile duct disorders (excl neoplasms)$Bile duct disorders$Hepatobiliary disorders MDR
PRIMARY_SOC 10019805 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3117634 RXNORM
RXAUI 3117671 RXNORM
RXAUI 3132833 RXNORM
RXAUI 3132834 RXNORM
RXCUI 1023457 RXNORM
SMQ_TERM_ADDVERSION 10.1 MDR
SMQ_TERM_ADDVERSION 19.0 MDR
SMQ_TERM_ADDVERSION 8.0 MDR
SMQ_TERM_ADDVERSION 9.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_CAT B MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 10.1 MDR
SMQ_TERM_LMVERSION 12.1 MDR
SMQ_TERM_LMVERSION 16.0 MDR
SMQ_TERM_LMVERSION 19.0 MDR
SMQ_TERM_LMVERSION 9.1 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 197446008 NDFRT
SNOMED_CID 30144000 NDFRT
SOS Excludes: congenital (751.61); that with calculus (574.3-574.5 with fifth-digit 1) ICD9CM
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS K83.1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~K83.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS K83.1 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS K83.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF CHOLESTASIS IN NEWBORN CHOOSE Q44.3 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF CHOLESTASIS OF PREGNANCY CHOOSE K83.1 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF CHOLESTASIS OF PREGNANCY CHOOSE O26.619 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | CONSIDER TRIMESTER SPECIFICATION | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF CHOLESTASIS OF PREGNANCY COMPLICATING CHILDBIRTH CHOOSE O26.62 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF CHOLESTASIS WITH PIGMENTARY RETINOPATHY AND CLEFT PALATE SYNDROME CHOOSE H35.52 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF CHOLESTASIS WITH PIGMENTARY RETINOPATHY AND CLEFT PALATE SYNDROME CHOOSE Q35.9 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INTRAHEPATIC CHOLESTASIS CHOOSE K71.0 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF NEONATAL INTRAHEPATIC CHOLESTASIS DUE TO CITRIN DEFICIENCY CHOOSE K83.1 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~5 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~6 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 10750161000119106 | Cholestasis of pregnancy complicating childbirth | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 235888006 | Cholestasis of pregnancy | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 433237003 | Cholestasis in newborn | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 4637005 | Intrahepatic cholestasis | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 717155003 | Neonatal intrahepatic cholestasis due to citrin deficiency | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 720636001 | Cholestasis with pigmentary retinopathy and cleft palate syndrome | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~H35.52 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~K71.0 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~K83.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~O26.619 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~O26.62 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~Q35.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~Q44.3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~J662. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~J6620 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUC19 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T008064 MSH
TERMUI T008065 MSH
TERMUI T008066 MSH
TH NLM (1972) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0008370

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