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Chenodeoxycholic Acid (CUI C0008024) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0008024

NCI Thesaurus Code: C65206  (see NCI Thesaurus info)

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

Semantic Type: Biologically Active Substance

MSH Definition: A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.

Synonyms & Abbreviations: (see Synonym Details)
3 alpha,7 alpha, Dihydroxycholanic acid
3alpha,7alpha-Dihydroxy-5beta-cholanic acid
7alpha-Hydroxylithocholic acid
Acid, Chenic
Acid, Chenique
Acid, Chenodeoxycholic
Acid, Gallodesoxycholic
Anthropodeoxycholic acid
Anthropodesoxycholic acid
CDCA - Chenodeoxycholic acid
CDCA
Chenic acid
Chenique Acid
Chenocholic acid
Chenodeoxycholic Acid [Chemical/Ingredient]
chenodeoxycholic acid
Chenodesoxycholic acid
Chenodiol (substance)
Chenodiol
Cholan-24-oic acid, 3,7-dihydroxy-, (3alpha,5beta,7alpha)-
Gallodesoxycholic acid
Henohol
Product containing chenodiol (medicinal product)
Product containing chenodiol

External Source Codes: 
NCI Thesaurus Code C65206 (see NCI Thesaurus info)
CAS Registry Number 474-25-9 (see NLM ChemIDplus info)
FDA UNII Code 0GEI24LG0J

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BI BL CF CH CL CS CT DF EC GE HI IM IP ME PD PH PK PO RE SD SE ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:16755 NCI
Chemical_Formula C24H40O4 NCI
Contributing_Source FDA NCI
CTV3ID am1.. SNOMEDCT_US
CTV3ID XM0l5 SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DX 19740101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FDA_UNII_CODE 0GEI24LG0J DRUGBANK
FDA_UNII_CODE 0GEI24LG0J NDFRT
HN 74(73) MSH
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones. NDFRT
MESH_DUI D002635 NDFRT
MESH_NAME Chenodeoxycholic Acid NDFRT
MESH_UI M0004029 NDFRT
MMR 20160528 MSH
MN D04.210.500.105.225.272.150 MSH
MN D04.210.500.221.430.342.300 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000005963 NDFRT
NUI N0000020371 NDFRT
NUI N0000146754 NDFRT
PA D002400 MSH
PA D005765 MSH
PM 74 MSH
RN 0GEI24LG0J MSH
RR 474-25-9 (Chenodeoxycholic Acid) MSH
RXAUI 2069527 RXNORM
RXAUI 2627524 RXNORM
RXAUI 3034427 RXNORM
RXAUI 3044270 RXNORM
RXAUI 3123601 RXNORM
RXAUI 3123602 RXNORM
RXAUI 3123606 RXNORM
RXAUI 3123607 RXNORM
RXAUI 3132268 RXNORM
RXAUI 3132269 RXNORM
RXAUI 3132270 RXNORM
RXAUI 3132271 RXNORM
RXAUI 3132274 RXNORM
RXAUI 3132712 RXNORM
RXAUI 3164665 RXNORM
RXAUI 3172064 RXNORM
RXAUI 71274 RXNORM
RXCUI 2323 RXNORM
SPL_SET_ID 769e0a3b-826d-4faf-9129-5eeb7ebe0b67 MTHSPL
SPL_SET_ID b8b4539b-31d1-40cb-b284-86cf8b16522a MTHSPL
SPL_SET_ID bbb86251-9423-40e6-9117-9511ab5fbf63 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~am1.. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XM0l5 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T007658 MSH
TERMUI T007659 MSH
TERMUI T007660 MSH
TERMUI T007661 MSH
TERMUI T007662 MSH
TERMUI T007663 MSH
TH BAN (19XX) MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH UNK (19XX) MSH
TH USAN (1978) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^1026^Active/Master NDFRT
VANDF_RECORD 50.6^729^Active/Master NDFRT
VUID 4018428 NDFRT
VUID 4022365 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0008024

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