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Cell Nucleus (CUI C0007610) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0007610

NCI Thesaurus Code: C13197  (see NCI Thesaurus info)

Semantic Type: Cell Component

NCIt Definition: A body within the cell, surrounded by a membrane, within which lie the chromosomes, one or more nucleoli, combined with proteins, and exhibits mitosis.

CDISC Definition: A body within the cell, surrounded by a membrane, within which lie the chromosomes, one or more nucleoli, combined with proteins, and exhibits mitosis. (NCI)

NCI-GLOSS Definition: In biology, the structure in a cell that contains the chromosomes. The nucleus has a membrane around it, and is where RNA is made from the DNA in the chromosomes.

CSP Definition: defining organelle of the eukaryotic cell; a membrane limited body which contains chromosomes and one or more nucleoli; the nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the endoplasmic reticulum.

MSH Definition: Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)

GO Definition: A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]

FMA Definition: Organelle which has as its direct parts a nuclear membrane and nuclear matrix.

Synonyms & Abbreviations: (see Synonym Details)
Cell Nuclei
cell nucleus
Nuclei, Cell
Nucleic
Nucleus (cell structure)
Nucleus of cell
Nucleus, Cell
NUCLEUS

External Source Codes: 
NCI Thesaurus Code C13197 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN A 11 qualif except /cytol; /genet permitted MSH
AQL CH CL DE EN GE IM ME MI PA PH PS RE SE UL VI MSH
AUTHORITY Bloom & Fawcett 1994:7 FMA
AUTHORITY rosse FMA
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000227009 SNOMEDCT_US
Contributing_Source CDISC NCI
CTV3ID XUMA9 SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 0593-3664 CSP
DX 19660101 MSH
EC transplantation:Nuclear Transfer Techniques MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FX D002451 MSH
FX D007620 MSH
GO_NAMESPACE cellular_component GO
GO_SUBSET goslim_aspergillus GO
GO_SUBSET goslim_candida GO
GO_SUBSET goslim_chembl GO
GO_SUBSET goslim_generic GO
GO_SUBSET goslim_metagenomics GO
GO_SUBSET goslim_pir GO
GO_SUBSET goslim_plant GO
GO_SUBSET goslim_yeast GO
GXR NIF_Subcellular:sao1702920020 GO
GXR Wikipedia:Cell_nucleus GO
MDA 19990101 MSH
MMR 20060705 MSH
MN A11.284.430.106 MSH
MN A11.284.430.214.190.875.117 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
SOS A membrane-bounded compartment in a eukaryotic cell which contains the genetic material and the nucleoli. The nucleus represents the control center of the cell. Responsible for DNA synthesis and repair, and for RNA synthesis. AOD
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUMA9 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T007188 MSH
TERMUI T007189 MSH
TH NLM (1966) MSH
TH NLM (1995) MSH
TRANSLATION German: Zelle Kern FMA
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
UWT Anatomical Structure UWDA

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0007610

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