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Carpal Tunnel Syndrome (CUI C0007286) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0007286

NCI Thesaurus Code: C34450  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: Entrapment of the median nerve in the wrist that is characterized by numbness, tingling and painful movement.

RADLEX Definition: Entrapment of the median nerve in the carpal tunnel, which is formed by the flexor retinaculum and the carpal bones. This syndrome may be associated with repetitive occupational trauma (cumulative trauma disorders); wrist injuries; amyloid neuropathies; rheumatoid arthritis (see arthritis, rheumatoid); acromegaly; pregnancy; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45) [MeSH]

MEDLINEPLUS Definition: 

You're working at your desk, trying to ignore the tingling or numbness you've had for some time in your hand and wrist. Suddenly, a sharp, piercing pain shoots through the wrist and up your arm. Just a passing cramp? It could be carpal tunnel syndrome.

The carpal tunnel is a narrow passageway of ligament and bones at the base of your hand. It contains nerve and tendons. Sometimes, thickening from irritated tendons or other swelling narrows the tunnel and causes the nerve to be compressed. Symptoms usually start gradually. As they worsen, grasping objects can become difficult.

Often, the cause is having a smaller carpal tunnel than other people do. Other causes include performing assembly line work, wrist injury, or swelling due to certain diseases, such as rheumatoid arthritis. Women are three times more likely to have carpal tunnel syndrome than men.

Early diagnosis and treatment are important to prevent permanent nerve damage. Your doctor diagnoses carpal tunnel syndrome with a physical exam and special nerve tests. Treatment includes resting your hand, splints, pain and anti-inflammatory medicines, and sometimes surgery.

NIH: National Institute of Neurological Disorders and Stroke

CSP Definition: entrapment of the median nerve in the carpal tunnel, which is formed by the flexor retinaculum and the carpal bones; this syndrome may be associated with repetitive occupational trauma, wrist injuries, amyloid neuropathies, rheumatoid arthritis, acromegaly, pregnancy, and other conditions; symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally; impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur.

MSH Definition: Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)

Synonyms & Abbreviations: (see Synonym Details)
Amyotrophy, Thenar, Of Carpal Origin
Carpal canal
carpal tunnel median neuropathy
Carpal tunnel syndrome (disorder)
Carpal Tunnel Syndrome [Disease/Finding]
Carpal tunnel syndrome, unspecified upper limb
Carpal Tunnel Syndromes
CARPAL TUNNEL SYNDROME
Carpal tunnel
CARPEL TUNNEL SYNDROME
Compression Neuropathy, Carpal Tunnel
CTS - Carpal tunnel syndrome
CTS1
CTS
Distal median nerve compression
Distal median nerve entrapment
Entrapment Neuropathy, Carpal Tunnel
Karpaltunnelsyndrom
MEDIAN NERVE COMPRESSION
Median nerve entrapment (disorder)
MEDIAN NERVE ENTRAPMENT
Median Neuropathy, Carpal Tunnel
SYNDROME CARPEL TUNNEL
Syndrome, Carpal Tunnel
Syndromes, Carpal Tunnel

External Source Codes: 
NCI Thesaurus Code C34450 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CTV3ID X75at SNOMEDCT_US
CTV3ID XE15g SNOMEDCT_US
DATE_CREATED 07/26/1999 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 2042-6577 CSP
DX 19650101 MSH
EFFECTIVE_TIME 20120731 SNOMEDCT_US
EFFECTIVE_TIME 20130731 SNOMEDCT_US
GENELOCUS ,1,8,q,1,1,.,2,-,q,1,2,.,1, OMIM
GENESYMBOL PALB OMIM
GENESYMBOL TTR OMIM
HN 1965(1963) MSH
IAN DEFAULT ICD10
ICE Median nerve entrapment; Partial thenar atrophy ICD9CM
IPX G56.0 ICPC
MDA 19990101 MSH
MESH_DEFINITION Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45) NDFRT
MESH_DUI D002349 NDFRT
MESH_NAME Carpal Tunnel Syndrome NDFRT
MESH_UI M0003553 NDFRT
MIMTYPE 3 OMIM
MIMTYPEMEANING Phenotype description, molecular basis known. OMIM
MIMTYPEVALUE pound OMIM
MMR 20120703 MSH
MN C10.668.829.500.500.200 MSH
MN C10.668.829.550.200 MSH
MN C26.844.150.206 MSH
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/carpaltunnelsyndrome.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Arabic https://www.nlm.nih.gov/medlineplus/languages/carpaltunnelsyndrome.html#Arabic MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/carpaltunnelsyndrome.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Neurological Disorders and Stroke http://www.ninds.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NUI N0000000693 NDFRT
ORDER_NO 06228 ICD10CM
ORDER_NO 06229 ICD10CM
PM 1965 MSH
PRIMARY_PATH 10007697$10027917$10034606$10029205$Carpal tunnel syndrome$Mononeuropathies$Peripheral neuropathies$Nervous system disorders MDR
PRIMARY_SOC 10029205 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3130693 RXNORM
RXAUI 3130694 RXNORM
RXAUI 3135217 RXNORM
RXAUI 3154399 RXNORM
RXAUI 3197015 RXNORM
RXAUI 5038638 RXNORM
RXCUI 1024790 RXNORM
SNOMED_CID 246611002 NDFRT
SNOMED_CID 57406009 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS G56.0 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~G56.0 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS G56.00 | CONSIDER LATERALITY SPECIFICATION | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS G56.00 | CONSIDER LATERALITY SPECIFICATION SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF BILATERAL CARPAL TUNNEL SYNDROME CHOOSE G56.01 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF CARPAL TUNNEL SYNDROME OF LEFT WRIST CHOOSE G56.02 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF CARPAL TUNNEL SYNDROME OF RIGHT WRIST CHOOSE G56.01 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 12265501000119101 | Bilateral carpal tunnel syndrome | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 293861000119102 | Carpal tunnel syndrome of left wrist | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 293871000119108 | Carpal tunnel syndrome of right wrist | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G56.00 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G56.01 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G56.02 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X75at SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XE15g SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T006779 MSH
TERMUI T370717 MSH
TERMUI T370718 MSH
TERMUI T370719 MSH
TERMUI T811441 MSH
TH NLM (1963) MSH
TH NLM (2000) MSH
TH OMIM (2013) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0007286

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