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Carnitine (CUI C0007258) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0007258

NCI Thesaurus Code: C82599  (see NCI Thesaurus info)

Semantic Type: Amino Acid, Peptide, or Protein

Semantic Type: Vitamin

Semantic Type: Pharmacologic Substance

NCIt Definition: An amino acid derivative. Carnitine facilitates long-chain fatty acid entry into mitochondria, delivering substrate for oxidation and subsequent energy production. Fatty acids are utilized as an energy substrate in all tissues except the brain.

MSH Definition: A constituent of STRIATED MUSCLE and LIVER. It is an amino acid derivative and an essential cofactor for fatty acid metabolism.

NCI-GLOSS Definition: A substance made in the muscle and liver tissue and found in certain foods, such as meat, poultry, fish, and some dairy products. It is used by many cells in the body to make energy from fatty acids.

CSP Definition: betaine derivative constituent of skeletal muscle and liver; required for mitochondrial beta oxidation of fatty acids; used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.

Synonyms & Abbreviations: (see Synonym Details)
(3-Carboxy-2-hydroxypropyl)trimethylammonium Hydroxide Inner Salt
1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, inner salt, (R)-
Carnitine (substance)
Carnitine [Chemical/Ingredient]
carnitines
carnitine

External Source Codes: 
NCI Thesaurus Code C82599 (see NCI Thesaurus info)
CAS Registry Number 461-06-3 (see NLM ChemIDplus info)
FDA UNII Code S7UI8SM58A

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BI BL CF CH CL CS CT DF EC GE HI IM IP ME PD PH PK PO RE SD SE ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHEBI_ID CHEBI:17126 NCI
CHEBI_ID CHEBI:3424 NCI
Chemical_Formula C7H15NO3 NCI
Contributing_Source FDA NCI
CTV3ID X80KT SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 0157-0806 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FDA_UNII_CODE S7UI8SM58A NDFRT
HN 66(64); was see under VITAMIN B COMPLEX 1963-65 MSH
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION A constituent of STRIATED MUSCLE and LIVER. It is an amino acid derivative and an essential cofactor for fatty acid metabolism. NDFRT
MESH_DUI D002331 NDFRT
MESH_NAME Carnitine NDFRT
MESH_UI M0003493 NDFRT
MMR 20141014 MSH
MN D02.092.877.883.099 MSH
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006688 NDFRT
NUI N0000148430 NDFRT
PM 66; was see under VITAMIN B COMPLEX 1963-65 MSH
RN S7UI8SM58A MSH
RR 0G389FZZ9M MSH
RR 541-15-1 MSH
RXAUI 2068846 RXNORM
RXAUI 3091477 RXNORM
RXAUI 3121534 RXNORM
RXAUI 3121535 RXNORM
RXAUI 3130603 RXNORM
RXAUI 3130621 RXNORM
RXAUI 3548918 RXNORM
RXAUI 64643 RXNORM
RXAUI 6841226 RXNORM
RXCUI 2106 RXNORM
RXN_ACTIVATED 01/28/2010 RXNORM
RXN_OBSOLETED 08/30/2007 RXNORM
SPL_SET_ID 0c2c1365-f4e2-4552-87e6-c5c41cf9a5be MTHSPL
SPL_SET_ID 32afd406-1f13-44dd-a195-ca2825d4c3b3 MTHSPL
SPL_SET_ID 3fcff8dc-ba5e-4633-8762-0bd4a58a479a MTHSPL
SPL_SET_ID 4325bda3-9af0-479a-a7e2-062dc1fb7ec6 MTHSPL
SPL_SET_ID 4a4eb814-da54-4522-a06c-0f850d4b5999 MTHSPL
SPL_SET_ID 54168b09-09b7-4952-925f-af85a7157709 MTHSPL
SPL_SET_ID 5e9c03c7-136d-46b5-a16a-a3419a5bc079 MTHSPL
SPL_SET_ID 96e4d5fe-f459-41f7-b446-342c12880223 MTHSPL
SPL_SET_ID 974d14c6-74b0-43b3-8218-13c94b730dc9 MTHSPL
SPL_SET_ID 9c3159a5-591b-4932-8f8f-8bae2d5edc25 MTHSPL
SPL_SET_ID accf470e-f8a0-4d3f-a4a6-33f3f912d536 MTHSPL
SPL_SET_ID b53e5739-c9f6-44e4-8032-c2bf24fa8398 MTHSPL
SPL_SET_ID b7e59721-9cac-4d7a-8a07-e82b48232e2f MTHSPL
SPL_SET_ID dddcf6ae-c803-45d8-ba3b-946f3a548b85 MTHSPL
SPL_SET_ID f90b2b29-9029-42c4-8b09-87bb9d5b2e50 MTHSPL
SPL_SET_ID fe88b2e3-18f7-4cf7-bacc-22b204eac76d MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~X80KT SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T006702 MSH
TH FDA SRS (2015) MSH
TH INN (19XX) MSH
TH NLM (1964) MSH
TH USAN (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^3617^Active/Master NDFRT
VUID 4020953 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0007258

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