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Noninfiltrating Intraductal Carcinoma (CUI C0007124) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0007124

NCI Thesaurus Code: C2924  (see NCI Thesaurus info)

Semantic Type: Neoplastic Process

NCIt Definition: A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS.

PDQ Definition: A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS. Check for active clinical trials using this agent. (NCI Thesaurus)

HPO Definition: Presence of abnormal cells inside a milk duct, that is, non-invasive breast cancer. Ductal carcinoma in situ is considered to be a precursor lesion to invasive breast cancer. [pmid:24415964]

NCI-GLOSS Definition: A noninvasive condition in which abnormal cells are found in the lining of a breast duct. The abnormal cells have not spread outside the duct to other tissues in the breast. In some cases, ductal carcinoma in situ may become invasive cancer and spread to other tissues, although it is not known at this time how to predict which lesions will become invasive.

CTEP Definition: CTEP_For_FDA: 90002012/Intraductal neoplasm NOS

MSH Definition: A noninvasive (noninfiltrating) carcinoma of the breast characterized by a proliferation of malignant epithelial cells confined to the mammary ducts or lobules, without light-microscopy evidence of invasion through the basement membrane into the surrounding stroma.

Synonyms & Abbreviations: (see Synonym Details)
Carcinoma in situ of breast ductal
Carcinoma, Intraductal, Noninfiltrating [Disease/Finding]
Carcinoma, Intraductal, Noninfiltrating
Carcinoma, Intraductal
Carcinoma, Noninfiltrating Intraductal
Carcinomas, Intraductal
Carcinomas, Noninfiltrating Intraductal
DCIS of the breast
DCIS, NOS
DCIS
Ductal Breast Carcinoma In Situ
ductal cancer in situ of the breast
Ductal Carcinoma In Situ (DCIS)
Ductal Carcinoma In Situ of Breast
Ductal Carcinoma In Situ of the Breast
Ductal carcinoma in situ, NOS
ductal carcinoma in situ
in situ ductal breast carcinoma
Intraductal adenocarcinoma, noninfiltrating, NOS
Intraductal adenocarcinoma, noninfiltrating
intraductal breast cancer
Intraductal Breast Carcinoma
Intraductal carcinoma in situ of breast (disorder)
Intraductal carcinoma in situ of breast
Intraductal carcinoma in situ
Intraductal carcinoma of breast (disorder)
Intraductal Carcinoma of Breast
Intraductal Carcinoma of the Breast
Intraductal carcinoma, noninfiltrating, no ICD-O subtype
Intraductal carcinoma, noninfiltrating, no International Classification of Diseases for Oncology subtype (morphologic abnormality)
Intraductal carcinoma, noninfiltrating, no International Classification of Diseases for Oncology subtype
Intraductal carcinoma, noninfiltrating, NOS
Intraductal Carcinoma, Noninfiltrating
Intraductal carcinoma, NOS
Intraductal Carcinomas, Noninfiltrating
Intraductal Carcinomas
intraductal carcinoma
Non-Infiltrating Ductal Adenocarcinoma of Breast
Non-Infiltrating Ductal Adenocarcinoma of the Breast
Non-Infiltrating Ductal Breast Adenocarcinoma
Non-Infiltrating Ductal Breast Carcinoma
Non-Infiltrating Ductal Carcinoma of Breast
Non-Infiltrating Ductal Carcinoma of the Breast
Non-Infiltrating Intraductal Adenocarcinoma of Breast
Non-Infiltrating Intraductal Adenocarcinoma of the Breast
Non-Infiltrating Intraductal Adenocarcinoma
Non-Infiltrating Intraductal Breast Adenocarcinoma
Non-Infiltrating Intraductal Carcinoma
Non-Invasive Ductal Adenocarcinoma of Breast
Non-Invasive Ductal Adenocarcinoma of the Breast
Non-Invasive Ductal Breast Adenocarcinoma
Non-Invasive Ductal Breast Carcinoma
Non-Invasive Ductal Carcinoma of Breast
Non-Invasive Ductal Carcinoma of the Breast
Non-Invasive Intraductal Adenocarcinoma of Breast
Non-Invasive Intraductal Adenocarcinoma of the Breast
Non-Invasive Intraductal Breast Adenocarcinoma
Noninfiltrating Intraductal Carcinomas
Noninfiltrating Intraductal Carcinoma

External Source Codes: 
NCI Thesaurus Code C2924 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN intraductal refers to mammary ducts only; do not confuse entry term CARCINOMA, INTRADUCTAL with CARCINOMA, DUCTAL; CARCINOMA, DUCTAL, BREAST; or CARCINOMA, PANCREATIC DUCTAL; coordinate IM with BREAST NEOPLASMS (IM) MSH
AQL BL BS CF CH CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SC SE SU TH UL UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CODE_REF (C50._) ICDO
Contributing_Source CTEP NCI
Contributing_Source CTRP NCI
CTV3ID X77nz SNOMEDCT_US
CTV3ID X78WW SNOMEDCT_US
CTV3ID Xa0bT SNOMEDCT_US
DATE_LAST_MODIFIED 2007-08-13 PDQ
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2000-1867 CSP
DID 2016-0671 CSP
DX 19940101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20020731 SNOMEDCT_US
HN 94; was CARCINOMA, DUCTAL 1963-93 MSH
IAN DEFAULT ICD10
ICD-O-3_Code 8500/2 NCI
ICD-O-3_CODE 8500/2 SNOMEDCT_US
MDA 19990101 MSH
MESH_DEFINITION A noninvasive (noninfiltrating) carcinoma of the breast characterized by a proliferation of malignant epithelial cells confined to the mammary ducts or lobules, without light-microscopy evidence of invasion through the basement membrane into the surrounding stroma. NDFRT
MESH_DUI D002285 NDFRT
MESH_NAME Carcinoma, Intraductal, Noninfiltrating NDFRT
MESH_UI M0003436 NDFRT
MMR 20160531 MSH
MN C04.557.470.200.025.275 MSH
MN C04.557.470.200.240.187.250 MSH
MN C04.557.470.615.275 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NCI_THESAURUS_CODE C2924 PDQ
NDFRT_KIND DISEASE_KIND NDFRT
Neoplastic_Status Malignant NCI
NUI N0000000672 NDFRT
OL use CARCINOMA, INTRADUCTAL, NONINFILTRATING to search CARCINOMA, DUCTAL 1966-93 MSH
ORDER_NO 02818 ICD10CM
ORIG_STY Neoplasm diagnosis PDQ
PID 2518 PDQ
PM 94; was CARCINOMA, DUCTAL 1963-93 MSH
RXAUI 3130302 RXNORM
RXAUI 3130303 RXNORM
RXAUI 3130304 RXNORM
RXAUI 3138367 RXNORM
RXAUI 3149249 RXNORM
RXAUI 3182657 RXNORM
RXCUI 1022096 RXNORM
SMQ_TERM_ADDVERSION 10.0 MDR
SMQ_TERM_ADDVERSION 11.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 14.0 MDR
SMQ_TERM_LMVERSION 20.0 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 109889007 NDFRT
SNOMED_CID 278053004 NDFRT
SUBSET_MEMBER 446608001~MAPTARGET~8500/2 SNOMEDCT_US
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS D05.1 | POSSIBLE REQUIREMENT FOR MORPHOLOGY CODE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~D05.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS D05.10 | CONSIDER LATERALITY SPECIFICATION SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INTRADUCTAL CARCINOMA IN SITU OF BILATERAL BREASTS CHOOSE D05.11 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INTRADUCTAL CARCINOMA IN SITU OF LEFT BREAST CHOOSE D05.12 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INTRADUCTAL CARCINOMA IN SITU OF RIGHT BREAST CHOOSE D05.11 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 1079811000119104 | Intraductal carcinoma in situ of left breast | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 1079821000119106 | Intraductal carcinoma in situ of right breast | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 15636951000119108 | Intraductal carcinoma in situ of bilateral breasts | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~D05.10 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~D05.11 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~D05.12 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X77nz SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X78WW SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~Xa0bT SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERM_LEVEL 4 ICDO
TERM_LEVEL Related ICDO
TERM_LEVEL Synonym ICDO
TERMUI T006580 MSH
TERMUI T006581 MSH
TERMUI T006582 MSH
TERMUI T006583 MSH
TERMUI T006584 MSH
TH NLM (1966) MSH
TH NLM (1994) MSH
TH NLM (1999) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0007124

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