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Betaine (CUI C0005304) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0005304

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

CSP Definition: class of trimethyl derivatives of amino acids or the internal salts of quaternary ammonium bases.

MSH Definition: A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341)

Synonyms & Abbreviations: (see Synonym Details)
2-trimethylammonioacetate
Betaine (substance)
Betaine [Chemical/Ingredient]
betaine compound
Betaine, Glycine
Betaine
Glycine betaine
Lycine
Methanaminium, 1-carboxy-N,N,N-trimethyl-, inner salt
Oxyneurine
Product containing betaine (medicinal product)
Product containing betaine
TMG
Trimethylglycine

External Source Codes:  (none)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CTV3ID XUcg7 SNOMEDCT_US
CTV3ID XUE0Y SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 0156-9564 CSP
DX 19680101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20050131 SNOMEDCT_US
FDA_UNII_CODE 3SCV180C9W DRUGBANK
FDA_UNII_CODE 3SCV180C9W NDFRT
HN 68(64) MSH
LEVEL Example Part D Eligible Drugs USPMG
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341) NDFRT
MESH_DUI D001622 NDFRT
MESH_NAME Betaine NDFRT
MESH_UI M0002435 NDFRT
MMR 20160705 MSH
MN D02.092.877.883.077 MSH
MN D02.675.276.125 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006734 NDFRT
NUI N0000147725 NDFRT
PA D005765 MSH
PA D008082 MSH
PM 68 MSH
RN 3SCV180C9W MSH
RR 107-43-7 (Betaine) MSH
RR 590-46-5 (HCl) MSH
RR JK8U8K4D6K MSH
RXAUI 2068563 RXNORM
RXAUI 3052137 RXNORM
RXAUI 3114681 RXNORM
RXAUI 3114682 RXNORM
RXAUI 3117514 RXNORM
RXAUI 3117521 RXNORM
RXAUI 3166261 RXNORM
RXAUI 3190433 RXNORM
RXAUI 3198200 RXNORM
RXAUI 3211550 RXNORM
RXAUI 3631004 RXNORM
RXAUI 4231257 RXNORM
RXAUI 46411 RXNORM
RXCUI 1512 RXNORM
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SPL_SET_ID fde605a7-75f3-4ee7-b882-ce8f6447bf66 MTHSPL
SPL_SET_ID fe80c9ef-62dd-43fc-9cf2-e04ee66b8689 MTHSPL
SPL_SET_ID ffd64693-8cb4-4ced-a7d4-eaeb1f310523 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUcg7 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUE0Y SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T004694 MSH
TERMUI T004695 MSH
TERMUI T004696 MSH
TERMUI T004697 MSH
TH FDA SRS (2014) MSH
TH NLM (1964) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^2251^Active/Master NDFRT
VANDF_RECORD 50.6^3402^Active/Master NDFRT
VUID 4019632 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0005304

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