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Benign prostatic hypertrophy (CUI C0005001) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0005001

NCI Thesaurus Code: C2897  (see NCI Thesaurus info)

Semantic Type: Neoplastic Process

NCIt Definition: A non-cancerous nodular enlargement of the prostate gland. It is characterized by the presence of epithelial cell nodules, and stromal nodules containing fibrous and smooth muscle elements. It is the most common urologic disorder in men, causing blockage of urine flow.

RADLEX Definition: PIRADS: A non-cancerous nodular enlargement of the transition zone of the prostate gland. It is characterized by the presence of glandular epithelial cell nodules, and stromal nodules containing fibrous and smooth muscle elements. Composed of BPH nodules.

HPO Definition: The presence of non-malignant hyperplasia of the prostate. [HPO:probinson]

MEDLINEPLUS Definition: 

The prostate is a gland in men. It helps make semen, the fluid that contains sperm. The prostate surrounds the tube that carries urine out of the body. As men age, their prostate grows bigger. If it gets too large, it can cause problems. An enlarged prostate is also called benign prostatic hyperplasia (BPH). Most men will get BPH as they get older. Symptoms often start after age 50.

BPH is not cancer, and it does not seem to increase your chance of getting prostate cancer. But the early symptoms are the same. Check with your doctor if you have

  • A frequent and urgent need to urinate, especially at night
  • Trouble starting a urine stream or making more than a dribble
  • A urine stream that is weak, slow, or stops and starts several times
  • The feeling that you still have to go, even just after urinating
  • Small amounts of blood in your urine

Severe BPH can cause serious problems over time, such as urinary tract infections, and bladder or kidney damage. If it is found early, you are less likely to develop these problems.

Tests for BPH include a digital rectal exam, blood and imaging tests, a urine flow study, and examination with a scope called a cystoscope. Treatments include watchful waiting, medicines, nonsurgical procedures, and surgery.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

NCI-GLOSS Definition: A benign (noncancerous) condition in which an overgrowth of prostate tissue pushes against the urethra and the bladder, blocking the flow of urine.

CSP Definition: enlargement or overgrowth of the prostate gland as a result of an increase in the number of its constituent cells.

MSH Definition: A disease caused by hyperplastic process of non-transformed prostatic cells.

Synonyms & Abbreviations: (see Synonym Details)
Benign enlargement of prostate
Benign Hyperplasia of Prostate
Benign Hyperplasia of the Prostate
Benign hypertrophy of prostate NOS
benign prostate hyperplasia
Benign prostatic hyperplasia (disorder)
Benign Prostatic Hyperplasia - BPH
benign prostatic hyperplasia
Benign Prostatic Hypertrophy
Benigne Prostatahyperplasie
BEP - Benign enlargement of prostate
BPH - benign prostatic hyperplasia
BPH
Enlarged prostate (benign)
Enlarged Prostate (BPH)
Hypertrophy (benign) of prostate
Hypertrophy, Benign Prostatic
Nodular hyperplasia of prostate gland
PROSTATE, HYPERTROPHY, BENIGN
Prostatic area hypertrophy
PROSTATIC HYPERPLASIA BENIGN <PROSTATISM>
Prostatic Hyperplasia, Benign
Prostatic hypertrophy (benign)
Prostatic Hypertrophy, Benign
Prostatic hypertrophy

External Source Codes: 
NCI Thesaurus Code C2897 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CITE PIRADS RADLEX
Contributing_Source CTRP NCI
CTV3ID XE0e6 SNOMEDCT_US
DATE_CREATED 06/03/2014 MEDLINEPLUS
DATE_FIRST_PUBLISHED 2006-12-01 PDQ
DATE_LAST_MODIFIED 07/07/2014 RADLEX
DATE_LAST_MODIFIED 2010-01-27 PDQ
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2587-6634 CSP
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EXCLUDES1 benign neoplasms of prostate (adenoma, benign) (fibroadenoma) (fibroma) (myoma) (D29.1) ICD10CM
EXCLUDES2 malignant neoplasm of prostate (C61) ICD10CM
IPX N40 ICPC
LAST_CHANGES_TO_CLASS def, source RADLEX
MIMTYPE 5 OMIM
MIMTYPEMEANING Mendelian phenotype or locus, molecular basis unknown. OMIM
MIMTYPEVALUE perc OMIM
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/enlargedprostatebph.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/enlargedprostatebph.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Diabetes and Digestive and Kidney Diseases http://www.niddk.nih.gov/ MEDLINEPLUS
NCI_THESAURUS_CODE C2897 PDQ
ORDER_NO 23481 ICD10CM
ORIG_STY Disease/diagnosis PDQ
PRIMARY_PATH 10004446$10036966$10036958$10038604$Benign prostatic hyperplasia$Prostatic neoplasms and hypertrophy$Prostatic disorders (excl infections and inflammations)$Reproductive system and breast disorders MDR
PRIMARY_SOC 10038604 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS N40 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~N40 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS N40.0 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF BENIGN PROSTATIC HYPERTROPHY WITH OUTFLOW OBSTRUCTION CHOOSE N13.8 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF BENIGN PROSTATIC HYPERTROPHY WITH OUTFLOW OBSTRUCTION CHOOSE N40.1 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 236646007 | Benign prostatic hypertrophy with outflow obstruction | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~N13.8 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~N40.0 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~N40.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XE0e6 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T033883 MSH
TERMUI T459340 MSH
TERMUI T459341 MSH
TH NLM (1992) MSH
TH NLM (2003) MSH
TH OMIM (2013) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0005001

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