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Astrocytoma (CUI C0004114) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0004114

NCI Thesaurus Code: C60781  (see NCI Thesaurus info)

Semantic Type: Neoplastic Process

NCIt Definition: A tumor of the brain or spinal cord showing astrocytic differentiation. It includes the following clinicopathological entities: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma, pleomorphic xanthoastrocytoma, and subependymal giant cell astrocytoma.

RADLEX Definition: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082) [MeSH]

HPO Definition: Astrocytoma is a neoplasm of the central nervous system derived from astrocytes. Astrocytes are a type of glial cell, and thus astrocytoma is a subtype of glioma. [HPO:curators]

NICHD Definition: A malignant neoplasm of the central nervous system that arises from astrocytes.

NCI-GLOSS Definition: A tumor that begins in the brain or spinal cord in small, star-shaped cells called astrocytes.

CSP Definition: neoplasms composed of astrocytes of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors.

MSH Definition: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Synonyms & Abbreviations: (see Synonym Details)
Astrocytoma [Disease/Finding]
Astrocytoma, no ICD-O subtype
Astrocytoma, no International Classification of Diseases for Oncology subtype (morphologic abnormality)
Astrocytoma, no International Classification of Diseases for Oncology subtype
Astrocytoma, NOS
Astrocytomas
astrocytoma
Astrozytom

External Source Codes: 
NCI Thesaurus Code C60781 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN coord IM with precoord CNS/neopl term (IM) + site (IM); Grades I-III go here, with pathol; for ASTROCYTOMA, GRADE IV see GLIOBLASTOMA; for SUBEPENDYMAL ASTROCYTOMA see GLIOMA, SUBEPENDYMAL; for MIXED OLIGODENDROGLIOMA-ASTROCYTOMA see OLIGODENDROGLIOMA MSH
AQL BL BS CF CH CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SC SE SU TH UL UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CODE_REF (C71._) ICDO
COMMENT use WHO grading system RADLEX
Contributing_Source CTRP NCI
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID Xa995 SNOMEDCT_US
DATE_CREATED 2009-01-28T10:51:01Z HPO
DATE_CREATED 2015-01-22T00:04:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2012-6768 CSP
DISEASE_IDENTIFIER_ID 34621 GARD
DX 19630101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
HN 1963; for ASTROCYTOMA, SUBEPENDYMAL GIANT CELL use GLIOMA 1994-1999 MSH
ICD-O-3_Code 9400/3 NCI
ICD-O-3_CODE 9400/3 SNOMEDCT_US
IDENTIFIER_SOURCE Orp GARD
IDENTIFIER_TYPE_ID 1 GARD
IS_ACTIVE true GARD
MDA 19990101 MSH
MESH_DEFINITION Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082) NDFRT
MESH_DUI D001254 NDFRT
MESH_NAME Astrocytoma NDFRT
MESH_UI M0001891 NDFRT
MMR 20120703 MSH
MN C04.557.465.625.600.380.080 MSH
MN C04.557.470.670.380.080 MSH
MN C04.557.580.625.600.380.080 MSH
NDFRT_KIND DISEASE_KIND NDFRT
Neoplastic_Status Undetermined NCI
NICHD_Hierarchy_Term Astrocytoma NCI
NUI N0000000501 NDFRT
PM 1963; for ASTROCYTOMA, SUBEPENDYMAL GIANT CELL see GLIOMA 1994-1999 MSH
PRIMARY_PATH 10003571$10029213$10029211$10029104$Astrocytoma$Nervous system neoplasms unspecified malignancy NEC$Nervous system neoplasms malignant and unspecified NEC$Neoplasms benign, malignant and unspecified (incl cysts and polyps) MDR
PRIMARY_SOC 10029104 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3112067 RXNORM
RXAUI 3112068 RXNORM
RXCUI 1024668 RXNORM
SMQ_TERM_ADDVERSION 10.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LMVERSION 20.0 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 254938000 NDFRT
SUBSET_MEMBER 446608001~MAPTARGET~9400/3 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~Xa995 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERM_LEVEL 4 ICDO
TERMUI T003752 MSH
TH NLM (1966) MSH
TH OMIM (2013) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0004114

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