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Astrocytes (CUI C0004112) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0004112

NCI Thesaurus Code: C12477  (see NCI Thesaurus info)

Semantic Type: Cell

NCIt Definition: A heterogeneous group of specialized neuroglial cells with many diverse supporting roles in the structure, function, and homeostasis of the central nervous system.

NCI-GLOSS Definition: A large, star-shaped cell that holds nerve cells in place and helps them develop and work the way they should. An astrocyte is a type of glial cell.

CSP Definition: neuroglial CNS cells of ectodermal origin characterized by fibrous, protoplasmic, or plasmatofibrous processes.

MSH Definition: A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.

Synonyms & Abbreviations: (see Synonym Details)
Astrocyte (cell)
Astrocytes
astrocyte
Astrocytus
Astroglias
Astroglia

External Source Codes: 
NCI Thesaurus Code C12477 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL CH CL CY DE EN IM ME MI PA PH PS RE SE TR UL VI MSH
AUTHORITY Gray's 99:939; Burt 93:44; Bloom & Fawcett 94:354-355 FMA
AUTHORITY Nomina Anatomica 1989 FMA
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CTV3ID XUKvD SNOMEDCT_US
DATE_LAST_MODIFIED Fri Jun 09 11:04:13 PDT 2000 FMA
DATE_LAST_MODIFIED Fri Jun 09 13:30:14 PDT 2000 FMA
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2047-3484 CSP
DX 19790101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FX D001812 MSH
HN 79(75); was see under NEUROGLIA 1963-78 MSH
MDA 19990101 MSH
MMR 20010725 MSH
MN A08.637.200 MSH
MN A11.650.200 MSH
OL search NEUROGLIA 1966-74 MSH
PM 79; was see under NEUROGLIA 1963-78 MSH
SOS Serves several functions, such as structural support for nerve cells, proliferation and repair after injury to the nerves, and isolation and grouping of nerve fibers and terminals; their interaction with neurons is of the utmost importance in the development of the CNS. AOD
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUKvD SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T003750 MSH
TERMUI T003751 MSH
TH NLM (1975) MSH
TH NLM (1994) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0004112

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