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Asthma (CUI C0004096) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0004096

NCI Thesaurus Code: C28397  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A chronic respiratory disease manifested as difficulty breathing due to the narrowing of bronchial passageways.

RADLEX Definition: A form of bronchial disorder associated with airway obstruction, marked by recurrent attacks of paroxysmal dyspnea, with wheezing due to spasmodic contraction of the bronchi. [MeSH]

HPO Definition: Asthma is characterized by increased responsiveness of the tracheobronchial tree to multiple stimuli, leading to narrowing of the air passages with resultant dyspnea, cough, and wheezing. [HPO:probinson]

MEDLINEPLUS Definition: 

Asthma is a chronic disease that affects your airways. Your airways are tubes that carry air in and out of your lungs. If you have asthma, the inside walls of your airways become sore and swollen. That makes them very sensitive, and they may react strongly to things that you are allergic to or find irritating. When your airways react, they get narrower and your lungs get less air.

Symptoms of asthma include

  • Wheezing
  • Coughing, especially early in the morning or at night
  • Chest tightness
  • Shortness of breath

Not all people who have asthma have these symptoms. Having these symptoms doesn't always mean that you have asthma. Your doctor will diagnose asthma based on lung function tests, your medical history, and a physical exam. You may also have allergy tests.

When your asthma symptoms become worse than usual, it's called an asthma attack. Severe asthma attacks may require emergency care, and they can be fatal.

Asthma is treated with two kinds of medicines: quick-relief medicines to stop asthma symptoms and long-term control medicines to prevent symptoms.

NIH: National Heart, Lung, and Blood Institute

NCI-GLOSS Definition: A chronic disease in which the bronchial airways in the lungs become narrowed and swollen, making it difficult to breathe. Symptoms include wheezing, coughing, tightness in the chest, shortness of breath, and rapid breathing. An attack may be brought on by pet hair, dust, smoke, pollen, mold, exercise, cold air, or stress.

NICHD Definition: A chronic respiratory disease caused by obstruction of the bronchi and small airways, and characterized by wheezing and shortness of breath.

CSP Definition: form of bronchial disorder associated with airway obstruction, marked by recurrent attacks of paroxysmal dyspnea, with wheezing due to spasmodic contraction of the bronchi.

MSH Definition: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Synonyms & Abbreviations: (see Synonym Details)
-- Asthma
Airway hyperreactivity
Asthma (disorder)
Asthma [Disease/Finding]
ASTHMA BRONCHIAL
Asthma NOS
ASTHMA, BRONCHIAL
Asthma, unspecified
Asthmas
Asthmatic
asthma
Br. asthma
Bronchial asthma
Bronchitic asthma
Unspecified asthma

External Source Codes: 
NCI Thesaurus Code C28397 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN note specifics; ASTHMA, CARDIAC see DYSPNEA, PAROXYSMAL is also available; in historical literature consider indexing "phthisic" here; "phthisis" probably goes under TUBERCULOSIS, PULMONARY MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
Contributing_Source FDA NCI
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID H33.. SNOMEDCT_US
DATE_CREATED 10/22/1998 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 1525-2157 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20040731 SNOMEDCT_US
EXCLUDES1 detergent asthma (J69.8) ICD10CM
EXCLUDES1 eosinophilic asthma (J82) ICD10CM
EXCLUDES1 lung diseases due to external agents (J60-J70) ICD10CM
EXCLUDES1 miner's asthma (J60) ICD10CM
EXCLUDES1 wheezing NOS (R06.2) ICD10CM
EXCLUDES1 wood asthma (J67.8) ICD10CM
EXCLUDES2 asthma with chronic obstructive pulmonary disease (J44.9) ICD10CM
EXCLUDES2 chronic asthmatic (obstructive) bronchitis (J44.9) ICD10CM
EXCLUDES2 chronic obstructive asthma (J44.9) ICD10CM
EXTERNALLY_DEFINED N LNC
FDA_Table Patient Code (Appendix B) NCI
FX D018927 MSH
HAS_GARD_PAGE true GARD
HN ETOH descriptor 2000. AOD
IAN DEFAULT ICD10
ICE Asthma (bronchial) (allergic NOS); Bronchitis: {allergic; asthmatic} ICD9CM
ICF The following fifth-digit subclassification is for use with codes 493.0-493.2,493.9; : {0 unspecified; 1 with status asthmaticus; 2 with (acute) exacerbation} ICD9CM
INCLUSION_TERM Asthmatic bronchitis NOS ICD10
INCLUSION_TERM Late-onset asthma ICD10
IPX -J45 ICPC
IPX -J46 ICPC
IS_RARE false GARD
IS_SPANISH false GARD
MDA 19990101 MSH
MESH_DEFINITION A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL). NDFRT
MESH_DUI D001249 NDFRT
MESH_NAME Asthma NDFRT
MESH_UI M0001885 NDFRT
MMR 20110624 MSH
MN C08.127.108 MSH
MN C08.381.495.108 MSH
MN C08.674.095 MSH
MN C20.543.480.680.095 MSH
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/asthma.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Amharic https://www.nlm.nih.gov/medlineplus/languages/asthma.html#Amharic MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Arabic https://www.nlm.nih.gov/medlineplus/languages/asthma.html#Arabic MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Bosnian https://www.nlm.nih.gov/medlineplus/languages/asthma.html#Bosnian MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Simplified https://www.nlm.nih.gov/medlineplus/languages/asthma.html#Chinese - Simplified MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Traditional https://www.nlm.nih.gov/medlineplus/languages/asthma.html#Chinese - Traditional MEDLINEPLUS
MP_OTHER_LANGUAGE_URL French https://www.nlm.nih.gov/medlineplus/languages/asthma.html#French MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Hindi https://www.nlm.nih.gov/medlineplus/languages/asthma.html#Hindi MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Japanese https://www.nlm.nih.gov/medlineplus/languages/asthma.html#Japanese MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Korean https://www.nlm.nih.gov/medlineplus/languages/asthma.html#Korean MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Portuguese https://www.nlm.nih.gov/medlineplus/languages/asthma.html#Portuguese MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Russian https://www.nlm.nih.gov/medlineplus/languages/asthma.html#Russian MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Somali https://www.nlm.nih.gov/medlineplus/languages/asthma.html#Somali MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/asthma.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Tagalog https://www.nlm.nih.gov/medlineplus/languages/asthma.html#Tagalog MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Ukrainian https://www.nlm.nih.gov/medlineplus/languages/asthma.html#Ukrainian MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Heart, Lung, and Blood Institute http://www.nhlbi.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Asthma NCI
NUI N0000000498 NDFRT
ORDER_NO 12582 ICD10CM
ORDER_NO 12600 ICD10CM
PRIMARY_PATH 10003553$10006484$10006436$10038738$Asthma$Bronchospasm and obstruction$Bronchial disorders (excl neoplasms)$Respiratory, thoracic and mediastinal disorders MDR
PRIMARY_SOC 10038738 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/10246/asthma/resources/1 GARD
RXAUI 3112044 RXNORM
RXAUI 3112045 RXNORM
RXAUI 3112046 RXNORM
RXAUI 3119104 RXNORM
RXCUI 1023235 RXNORM
SID HP:0002112 HPO
SMQ_TERM_ADDVERSION 12.0 MDR
SMQ_TERM_ADDVERSION 16.0 MDR
SMQ_TERM_ADDVERSION 8.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_CAT B MDR
SMQ_TERM_CAT C MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 12.0 MDR
SMQ_TERM_LMVERSION 16.0 MDR
SMQ_TERM_LMVERSION 8.1 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 195967001 NDFRT
SNOMED_CID 195979001 NDFRT
SOS Excludes: wheezing NOS (786.07) ICD9CM
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS J45.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~J45.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS J45.909 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~J45.909 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~H33.. SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T003741 MSH
TERMUI T003742 MSH
TERMUI T003743 MSH
TH NLM (1966) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
USE_ADDITIONAL code to identify: ICD10CM
USE_ADDITIONAL exposure to environmental tobacco smoke (Z77.22) ICD10CM
USE_ADDITIONAL exposure to tobacco smoke in the perinatal period (P96.81) ICD10CM
USE_ADDITIONAL history of tobacco dependence (Z87.891) ICD10CM
USE_ADDITIONAL occupational exposure to environmental tobacco smoke (Z57.31) ICD10CM
USE_ADDITIONAL tobacco dependence (F17.-) ICD10CM
USE_ADDITIONAL tobacco use (Z72.0) ICD10CM

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0004096

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