|Terms & Properties|
Concept Unique Identifier (CUI): C0004030
NCI Thesaurus Code: C2886 (see NCI Thesaurus info)
Semantic Type: Disease or Syndrome
NCIt Definition: An infection that is caused by Aspergillus.
RADLEX Definition: Aspergillosis is an infection, growth, or allergic response due to the Aspergillus fungus
GARD Definition: Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas. - this information is from GARD/ORDR/NCATS.
Aspergillosis is a disease caused by a fungus (or mold) called Aspergillus. The fungus is very common in both indoors and outdoors. Most people breathe in the spores of the fungus every day without being affected. But some people get the disease. It usually occurs in people with lung diseases or weakened immune systems.
There are different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA). Symptoms of ABPA include wheezing and coughing. ABPA can affect healthy people but it is most common in people with asthma or cystic fibrosis.
Another kind is invasive aspergillosis, which damages tissues in the body. It usually affects the lungs. Sometimes it can also cause infection in other organs and spread throughout the body. It affects people who have immune system problems, such as people who have had a transplant, are taking high doses of steroids, or getting chemotherapy for some cancers.
Your doctor might do a variety of tests to make the diagnosis, including a chest x-ray, CT scan of the lungs, and an examination of tissues for signs of the fungus. Treatment is with antifungal drugs. If you have ABPA, you may also take steroids.
Centers for Disease Control and Prevention
NCI-GLOSS Definition: An infectious fungal disease that occurs most often in the skin, ears, nasal sinuses, and lungs of people with suppressed immune systems.
NICHD Definition: A group of diseases which result from an infection with, or allergic response to the fungus Aspergillus.
CSP Definition: disease condition caused by species of Aspergillus and marked by inflammatory granulomatous lesions in the skin, ear, orbit, nasal sinuses, lungs, and sometimes in the bones and meninges.
MSH Definition: Infections with fungi of the genus ASPERGILLUS.
Synonyms & Abbreviations: (see Synonym Details)
|Infection due to Aspergillus|
External Source Codes:
|NCI Thesaurus Code||C2886 (see NCI Thesaurus info)|
|AN||specify species (IM) if pertinent; coordinate IM with precoordinated organ/disease term (IM); note PULMONARY ASPERGILLOSIS and specifics and NEUROASPERGILLOSIS are also available||MSH|
|AQL||BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH TM UR VE VI||MSH|
|ICE||Infection by Aspergillus species, mainly A. fumigatus, A. flavus group, A. terreus group||ICD9CM|
|MESH_DEFINITION||Infections with fungi of the genus ASPERGILLUS.||NDFRT|
|MP_PRIMARY_INSTITUTE_URL||National Institute of Allergy and Infectious Diseases http://www.niaid.nih.gov/||MEDLINEPLUS|
|SUBSET_MEMBER||6011000124106~MAPADVICE~ALWAYS B44.9 | DESCENDANTS NOT EXHAUSTIVELY MAPPED||SNOMEDCT_US|
Additional Concept Data: (none)