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Aspergillosis (CUI C0004030) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0004030

NCI Thesaurus Code: C2886  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: An infection that is caused by Aspergillus.

RADLEX Definition: Aspergillosis is an infection, growth, or allergic response due to the Aspergillus fungus

GARD Definition: Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas. - this information is from GARD/ORDR/NCATS.

MEDLINEPLUS Definition: 

Aspergillosis is a disease caused by a fungus (or mold) called Aspergillus. The fungus is very common in both indoors and outdoors. Most people breathe in the spores of the fungus every day without being affected. But some people get the disease. It usually occurs in people with lung diseases or weakened immune systems.

There are different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA). Symptoms of ABPA include wheezing and coughing. ABPA can affect healthy people but it is most common in people with asthma or cystic fibrosis.

Another kind is invasive aspergillosis, which damages tissues in the body. It usually affects the lungs. Sometimes it can also cause infection in other organs and spread throughout the body. It affects people who have immune system problems, such as people who have had a transplant, are taking high doses of steroids, or getting chemotherapy for some cancers.

Your doctor might do a variety of tests to make the diagnosis, including a chest x-ray, CT scan of the lungs, and an examination of tissues for signs of the fungus. Treatment is with antifungal drugs. If you have ABPA, you may also take steroids.

Centers for Disease Control and Prevention

NICHD Definition: A group of diseases which result from an infection with, or allergic response to the fungus Aspergillus.

NCI-GLOSS Definition: An infectious fungal disease that occurs most often in the skin, ears, nasal sinuses, and lungs of people with suppressed immune systems.

CSP Definition: disease condition caused by species of Aspergillus and marked by inflammatory granulomatous lesions in the skin, ear, orbit, nasal sinuses, lungs, and sometimes in the bones and meninges.

MSH Definition: Infections with fungi of the genus ASPERGILLUS.

Synonyms & Abbreviations: (see Synonym Details)
Aspergilloses
Aspergillosis (disorder)
Aspergillosis [Disease/Finding]
Aspergillosis NOS
Aspergillosis, unspecified
aspergillosis
Infection due to Aspergillus

External Source Codes: 
NCI Thesaurus Code C2886 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN specify species (IM) if pertinent; coordinate IM with precoordinated organ/disease term (IM); note PULMONARY ASPERGILLOSIS and specifics and NEUROASPERGILLOSIS are also available MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH TM UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID AB63. SNOMEDCT_US
DATE_CREATED 10/04/2010 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 1988-4002 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020731 SNOMEDCT_US
HAS_GARD_PAGE true GARD
IAN DEFAULT ICD10
ICE Infection by Aspergillus species, mainly A. fumigatus, A. flavus group, A. terreus group ICD9CM
INCLUSION_TERM aspergilloma ICD10
IS_RARE true GARD
IS_SPANISH false GARD
LAST_REVIEW_DATE 2009-10-20T00:00:00 GARD
MDA 19990101 MSH
MESH_DEFINITION Infections with fungi of the genus ASPERGILLUS. NDFRT
MESH_DUI D001228 NDFRT
MESH_NAME Aspergillosis NDFRT
MESH_UI M0001850 NDFRT
MMR 20160630 MSH
MN C01.703.080 MSH
MN C01.703.295.328.249 MSH
MN C01.703.534.045 MSH
MN C17.800.838.208.416.249 MSH
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/aspergillosis.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/aspergillosis.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Allergy and Infectious Diseases http://www.niaid.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Aspergillosis NCI
NUI N0000000492 NDFRT
ORDER_NO 00985 ICD10CM
ORDER_NO 00993 ICD10CM
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/5856/aspergillosis/resources/1 GARD
RXAUI 3111989 RXNORM
RXAUI 3111990 RXNORM
RXCUI 1025666 RXNORM
SMQ_TERM_ADDVERSION 20.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 20.1 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 65553006 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS B44.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~B44.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS B44.9 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~B44.9 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~AB63. SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T003684 MSH
TH NLM (1966) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0004030

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