|Terms & Properties|
Concept Unique Identifier (CUI): C0002771
NCI Thesaurus Code: C241 (see NCI Thesaurus info)
Semantic Type: Biologically Active Substance
Semantic Type: Pharmacologic Substance
NCIt Definition: Compounds that alleviate pain without loss of consciousness. Analgesics act by various mechanisms including binding with opioid receptors and decreasing inflammation. Choice of analgesic may be determined by the type of pain. These compounds include opioid, non-opioid and adjuvant analgesic agents.
Pain relievers are medicines that reduce or relieve headaches, sore muscles, arthritis, or other aches and pains. There are many different pain medicines, and each one has advantages and risks. Some types of pain respond better to certain medicines than others. Each person may also have a slightly different response to a pain reliever.
Over-the-counter (OTC) medicines are good for many types of pain. There are two main types of OTC pain medicines: acetaminophen (Tylenol) and nonsteroidal anti-inflammatory drugs (NSAIDs). Aspirin, naproxen (Aleve), and ibuprofen (Advil, Motrin) are examples of OTC NSAIDs.
If OTC medicines don't relieve your pain, your doctor may prescribe something stronger. Many NSAIDs are also available at higher prescription doses. The most powerful pain relievers are narcotics. They are very effective, but they can sometimes have serious side effects. Because of the risks, you must use them only under a doctor's supervision.
There are many things you can do to help ease pain. Pain relievers are just one part of a pain treatment plan.
NCI-GLOSS Definition: Drugs that reduce pain. These drugs include aspirin, acetaminophen, and ibuprofen.
CSP Definition: compounds capable of relieving pain without the loss of consciousness or without producing anesthesia.
MSH Definition: Compounds that show activity in animal models of human PAIN such as tail flick and hot plate assays.
MSH Definition: Compounds capable of relieving pain without the loss of CONSCIOUSNESS.
Synonyms & Abbreviations: (see Synonym Details)
External Source Codes:
|NCI Thesaurus Code||C241 (see NCI Thesaurus info)|
|AN||general or unspecified; prefer specific groups||MSH|
|AQL||AD AE AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR||MSH|
|HN||78; ANALGESICS AND ANTIPYRETICS was heading 1963-77||MSH|
|MP_OTHER_LANGUAGE_URL||Chinese - Traditional https://www.nlm.nih.gov/medlineplus/languages/painrelievers.html#Chinese - Traditional||MEDLINEPLUS|
|OL||use ANALGESICS to search ANALGESICS AND ANTIPYRETICS 1966-77||MSH|
|PM||78; ANALGESICS AND ANTIPYRETICS was heading 1963-77||MSH|
|SOS||A major classification of drugs that produce relief from, or diminish sensitivity to, pain (analgesia) without loss of consciousness; sometimes also called anodynes. Analgesics may be divided into three basic categories: (1) the opiate narcotics, for example, opium, codeine, morphine, meperidine hydrochloride, hydromorphone hydrochloride, heroin, and methadone hydrochloride; (2) nonnarcotic prescription drugs; (3) nonnarcotic, non-prescription, mild analgesics, for example, aspirin (acetylsalicylic acid) and acetaminophen. In contemporary Western culture, the analgesics have been the major source for drug addiction and there has been a continuing, as yet unsuccessful, effort to produce a "nonaddictive analgesic".||AOD|
|SOS||Substances that reduce pain and that may or may not have other psychoactive properties. See *+ZQ opioids*. Drugs that relieve pain without blocking the conduction of nerve impulses or markedly altering the function of the sensory apparatus. The narcotic analgesics act on the central nervous system, produce dependence, and alter the patient's perception; they are primarily used for severe pain. The nonnarcotic analgesics act at the site of pain, do not produce dependence, and do not alter the patient's perception; they are used for mild to moderate pain.||AOD|
Additional Concept Data: (none)