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Amobarbital (CUI C0002640) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0002640

NCI Thesaurus Code: C76523  (see NCI Thesaurus info)

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

MSH Definition: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)

Synonyms & Abbreviations: (see Synonym Details)
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(3-methylbutyl)-
5-Ethyl-5-(3-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
Amobarbital (substance)
Amobarbital [Chemical/Ingredient]
amobarbital
Amylobarbitone
Pentymal
Product containing amobarbital (medicinal product)
Product containing amobarbital

External Source Codes: 
NCI Thesaurus Code C76523 (see NCI Thesaurus info)
CAS Registry Number 57-43-2 (see NLM ChemIDplus info)
FDA UNII Code GWH6IJ239E

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:2673 NCI
Chemical_Formula C11H18N2O3 NCI
Contributing_Source FDA NCI
CTV3ID x000K SNOMEDCT_US
CTV3ID XUW1V SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2517-5236 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20020731 SNOMEDCT_US
FDA_UNII_CODE GWH6IJ239E DRUGBANK
FDA_UNII_CODE GWH6IJ239E NDFRT
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565) NDFRT
MESH_DUI D000654 NDFRT
MESH_NAME Amobarbital NDFRT
MESH_UI M0001000 NDFRT
MMR 20160527 MSH
MN D03.383.742.698.253.077 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000005827 NDFRT
NUI N0000145880 NDFRT
PA D006993 MSH
PA D018757 MSH
RN GWH6IJ239E MSH
RR 57-43-2 (Amobarbital) MSH
RR 64-43-7 (Na) MSH
RR G0313KNC7D MSH
RXAUI 1833226 RXNORM
RXAUI 2067786 RXNORM
RXAUI 3092258 RXNORM
RXAUI 3100407 RXNORM
RXAUI 3100408 RXNORM
RXAUI 3108553 RXNORM
RXAUI 3108556 RXNORM
RXAUI 3108674 RXNORM
RXAUI 3218819 RXNORM
RXAUI 6394959 RXNORM
RXCUI 1805546 RXNORM
RXCUI 719 RXNORM
SOS A common, intermediate-acting barbiturate. AOD
SOS Manufactured as Amytal and, in a different form, as Amytal Sodium. Classification: sedative/hypnotics. AOD
SPL_SET_ID a2523317-e071-4e04-9d9f-9053286e0ce2 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~x000K SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUW1V SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T001952 MSH
TERMUI T001953 MSH
TERMUI T001954 MSH
TH BAN (19XX) MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH UNK (19XX) MSH
TH USP (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^86^Active/Master NDFRT
VANDF_RECORD 50.6^48^Active/Master NDFRT
VUID 4017494 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0002640

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