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Spectinomycin (CUI C0001268) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0001268

NCI Thesaurus Code: C61951  (see NCI Thesaurus info)

Semantic Type: Organic Chemical

Semantic Type: Antibiotic

NCIt Definition: An aminocyclitol aminoglycoside antibiotic derived from Streptomyces spectabilis with bacteriostatic activity. Spectinomycin binds to the bacterial 30S ribosomal subunit. As a result, this agent interferes with the initiation of protein synthesis and with proper protein elongation. This eventually leads to bacterial cell death.

MSH Definition: An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of GONORRHEA.

Synonyms & Abbreviations: (see Synonym Details)
4H-Pyrano(2,3-b)(1,4)benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, (2R-(2alpha,4abeta,5abeta,6beta,7beta,8beta,9alpha,9aalpha,10abeta))-
Actinospectacina
Actinospectacin
Espectinomicina
Product containing spectinomycin (medicinal product)
Product containing spectinomycin
SCM
Spectinomicina
Spectinomycin (substance)
Spectinomycin [Chemical/Ingredient]
Spectinomycine
Spectinomycinum
Spectinomycin

External Source Codes: 
NCI Thesaurus Code C61951 (see NCI Thesaurus info)
CAS Registry Number 1695-77-8 (see NLM ChemIDplus info)
FDA UNII Code 93AKI1U6QF

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BI BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Chemical_Formula C14H24N2O7 NCI
Contributing_Source FDA NCI
CTV3ID eb6.. SNOMEDCT_US
CTV3ID XUW2L SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DX 19730101 MSH
EFFECTIVE_TIME 20020731 SNOMEDCT_US
EFFECTIVE_TIME 20160131 SNOMEDCT_US
FDA_UNII_CODE 93AKI1U6QF DRUGBANK
FDA_UNII_CODE 93AKI1U6QF NDFRT
HN 93; was ACTINOSPECTACIN 1973-92; SPECTINOMYCIN was see ACTINOSPECTACIN 1978-92 MSH
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea. NDFRT
MESH_DUI D000198 NDFRT
MESH_NAME Spectinomycin NDFRT
MESH_UI M0000292 NDFRT
MMR 20160705 MSH
MN D03.383.188.712 MSH
MN D03.633.300.835 MSH
MN D09.408.051.836 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006595 NDFRT
NUI N0000148017 NDFRT
OL use SPECTINOMYCIN to search ACTINOSPECTACIN 1966-92 (as Prov 1966-72) MSH
PA D000900 MSH
PM 93; was ACTINOSPECTACIN 1965-92 (Prov 1965-72); SPECTINOMYCIN was see ACTINOSPECTACIN 1978-92 MSH
RN 93AKI1U6QF MSH
RR 1695-77-8 (Spectinomycin) MSH
RR 22189-32-8 (di-HCl, pentahydrate) MSH
RR 296JEI210Z MSH
RR HWT06H303Z MSH
RXAUI 2074452 RXNORM
RXAUI 3021759 RXNORM
RXAUI 3093807 RXNORM
RXAUI 3105858 RXNORM
RXAUI 3235353 RXNORM
RXAUI 3235354 RXNORM
RXAUI 3239548 RXNORM
RXAUI 3239552 RXNORM
RXAUI 3503841 RXNORM
RXAUI 6395902 RXNORM
RXAUI 7746 RXNORM
RXCUI 270 RXNORM
SID APRD01232 DRUGBANK
SPL_SET_ID 03974f03-924f-44e6-bb88-8850f4d9a211 MTHSPL
SPL_SET_ID 0e3be1f5-9375-4837-b47d-5b3cf364f10f MTHSPL
SPL_SET_ID 10b21053-d173-4c6f-b867-5efcab9d3420 MTHSPL
SPL_SET_ID 24c2c29d-bb24-4a67-9e7d-4012dbedd089 MTHSPL
SPL_SET_ID 78b88351-cfe4-40b5-8cb4-66244b7ccd1d MTHSPL
SPL_SET_ID ae3a3afa-debf-44d1-8378-d3227e3d0488 MTHSPL
SPL_SET_ID e161433d-baa9-4e29-b2ee-232ea40d7756 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~eb6.. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUW2L SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T000562 MSH
TERMUI T000563 MSH
TH BAN (19XX) MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH NLM (1993) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^2557^Active/Master NDFRT
VANDF_RECORD 50.6^412^Active/Master NDFRT
VUID 4019932 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0001268

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