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Acquired Immunodeficiency Syndrome (CUI C0001175) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0001175

NCI Thesaurus Code: C2851  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV). It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes. Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. Patients with AIDS are especially susceptible to opportunistic infections (usually pneumocystis carinii pneumonia, cytomegalovirus (CMV) infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin lymphoma and Kaposi sarcoma). The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood.

NICHD Definition: A chronic, potentially life threatening condition that is caused by human immunodeficiency virus (HIV) infection, and is characterized by increased susceptibility to opportunistic infections, certain cancers and neurologic disorders.

NCI-GLOSS Definition: A disease caused by human immunodeficiency virus (HIV). People with acquired immunodeficiency syndrome are at an increased risk for developing certain cancers and for infections that usually occur only in individuals with a weak immune system.

CSP Definition: one or more indicator diseases, depending on laboratory evidence of HIV infection (CDC); late phase of HIV infection characterized by marked suppression of immune function resulting in opportunistic infections, neoplasms, and other systemic symptoms (NIAID).

MSH Definition: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.

Synonyms & Abbreviations: (see Synonym Details)
ACQUIRED IMMUNE DEFIC SYNDROME
Acquired Immune Deficiency Syndrome (AIDS)
Acquired immune deficiency syndrome (disorder)
acquired immune deficiency syndrome
Acquired immune deficiency syndr
Acquired Immune Deficiency
ACQUIRED IMMUNO DEFIC SYNDROME
Acquired immuno deficiency syndrome
Acquired Immuno-Deficiency Syndromes
Acquired Immuno-Deficiency Syndrome
ACQUIRED IMMUNODEFIC SYNDROME
Acquired Immunodeficiency Disease
Acquired Immunodeficiency Syndrome [Disease/Finding]
Acquired immunodeficiency syndrome NOS
Acquired Immunodeficiency Syndrome, AIDS
Acquired immunodeficiency syndrome, unspecified
Acquired immunodeficiency syndromes
acquired immunodeficiency syndrome
AIDS - Acquired immunodeficiency syndrome
AIDS, Acquired Immunodeficiency Syndrome
AIDS
AUTOIMMUNE DEFICIENCY SYNDROME
IMMUNE DEFICIENCY SYNDROME ACQUIRED <AIDS>
Immuno-Deficiency Syndrome, Acquired
Immuno-Deficiency Syndromes, Acquired
IMMUNODEFIC SYNDROME ACQUIRED
Immunodeficiency due to human immunodeficiency virus infection
Immunodeficiency Syndrome, Acquired
Immunodeficiency Syndromes, Acquired
IMMUNOL DEFIC SYNDROME ACQUIRED
Immunologic Deficiency Syndrome, Acquired
Syndrome, Acquired Immuno-Deficiency
Syndrome, Acquired Immunodeficiency
Syndromes, Acquired Immuno-Deficiency
Syndromes, Acquired Immunodeficiency

External Source Codes: 
NCI Thesaurus Code C2851 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN caused by HIV; coord IM with HIV-1 or HIV-2 (IM) if pertinent; /epidemiol: consider also HIV SEROPREVALENCE; AIDS-RELATED OPPORTUNISTIC INFECTIONS is available if particularly discussed: see note there; for lymphoma with AIDS, use LYMPHOMA, AIDS-RELATED MSH
ANSWER_CODE 10560 LNC
ANSWER_CODE_SYSTEM NNDSS LNC
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH TM UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
Contributing_Source FDA NCI
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID XE0RX SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 1560-6271 CSP
DX 19830101 MSH
EFFECTIVE_TIME 20160131 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
FDA_Table Patient Code (Appendix B) NCI
FX D006679 MSH
FX D015492 MSH
FX D015526 MSH
FX D015528 MSH
FX D016483 MSH
FX D020943 MSH
HN 83 MSH
MDA 19830318 MSH
MESH_DEFINITION An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993. NDFRT
MESH_DUI D000163 NDFRT
MESH_NAME Acquired Immunodeficiency Syndrome NDFRT
MESH_UI M0000245 NDFRT
MMR 20040713 MSH
MN C02.782.815.616.400.040 MSH
MN C02.800.801.400.040 MSH
MN C02.839.040 MSH
MN C20.673.480.040 MSH
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Acquired Immunodeficiency Disease NCI
NUI N0000000291 NDFRT
PM 83 MSH
PRIMARY_PATH 10000565$10038997$10047438$10021881$Acquired immunodeficiency syndrome$Retroviral infections$Viral infectious disorders$Infections and infestations MDR
PRIMARY_SOC 10021881 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3096269 RXNORM
RXAUI 3105699 RXNORM
RXAUI 3105701 RXNORM
RXAUI 3105703 RXNORM
RXAUI 3105704 RXNORM
RXAUI 3178514 RXNORM
RXAUI 3178678 RXNORM
RXCUI 1022762 RXNORM
SNOMED_CID 62479008 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS B24 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~B24 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS B20 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF ACQUIRED IMMUNE DEFICIENCY SYNDROME COMPLICATING CHILDBIRTH CHOOSE B20 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF ACQUIRED IMMUNE DEFICIENCY SYNDROME COMPLICATING CHILDBIRTH CHOOSE O98.72 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 10746341000119109 | Acquired immune deficiency syndrome complicating childbirth | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~B20 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~O98.72 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XE0RX SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T000473 MSH
TERMUI T000474 MSH
TERMUI T000475 MSH
TERMUI T000476 MSH
TERMUI T000477 MSH
TERMUI T000478 MSH
TH BIOETHICS (1983) MSH
TH NLM (1986) MSH
TH POPLINE (1986) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0001175

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