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Acetylcholine (CUI C0001041) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0001041

NCI Thesaurus Code: C77840  (see NCI Thesaurus info)

Semantic Type: Biologically Active Substance

Semantic Type: Pharmacologic Substance

Semantic Type: Organic Chemical

NCI-GLOSS Definition: A chemical made by some types of nerve cells. It is used to send messages to other cells, including other nerve cells, muscle cells, and gland cells. It is released from the nerve ending and carries signals to cells on the other side of a synapse (space between nerve cells and other cells). Acetylcholine helps control memory and the action of certain muscles. It is a type of neurotransmitter.

CSP Definition: neurotransmitter; in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.

MSH Definition: A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.

Synonyms & Abbreviations: (see Synonym Details)
2-(Acetyloxy)-N,N,N-trimethylethanaminium
Acetylcholine (substance)
Acetylcholine [Chemical/Ingredient]
acetylcholine
Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-
Product containing acetylcholine (medicinal product)
Product containing acetylcholine

External Source Codes: 
NCI Thesaurus Code C77840 (see NCI Thesaurus info)
CAS Registry Number 51-84-3 (see NLM ChemIDplus info)
FDA UNII Code N9YNS0M02X

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BI BL CF CH CL CS CT DF EC GE HI IM IP ME PD PH PK PO RE SD SE ST TO TU UR MSH
AUTHORITY Gray's 99:935-936; Burt 93:97 FMA
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:15355 NCI
Chemical_Formula C7H16NO2 NCI
Contributing_Source FDA NCI
CTV3ID XU7ZM SNOMEDCT_US
CTV3ID XUGlR SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 0663-0733 CSP
DX 19600101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
FDA_UNII_CODE N9YNS0M02X DRUGBANK
FDA_UNII_CODE N9YNS0M02X NDFRT
FX D011950 MSH
HN 1998; for MIOCHOL use ACETYLCHOLINE (NM) 1981-1997; for CHLOROACETYLCHOLINE use ACETYLCHOLINE (NM) 1969-2000; for BROMOACETYLCHOLINE use ACETYLCHOLINE (NM) 1969-2000 MSH
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. NDFRT
MESH_DUI D000109 NDFRT
MESH_NAME Acetylcholine NDFRT
MESH_UI M0000165 NDFRT
MMR 20160705 MSH
MN D02.092.211.111 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006306 NDFRT
NUI N0000147690 NDFRT
PA D014665 MSH
PA D018679 MSH
PM 1998; MIOCHOL (now ACETYLCHOLINE) was indexed under ACETYLCHOLINE & MANNITOL 1981-97; CHLOROACETYLCHOLINE was indexed under ACETYLCHOLINE 1975-2000 & under CHLORINE 1974-1975; BROMOACETYLCHOLINE was indexed under ACETYLCHOLINE/analogs & derivatives 1974-2000 & ACETYLCHOLINE 1969-1974 MSH
RN N9YNS0M02X MSH
RR 2260-50-6 MSH
RR 51-84-3 (Acetylcholine) MSH
RR 52978-03-7 MSH
RR 56-13-3 MSH
RR 60-31-1 (Acetylcholine Chloride) MSH
RR 66-23-9 (Acetylcholine Bromide) MSH
RR 7632-27-1 MSH
RR 77822-10-7 MSH
RR 78213-25-9 MSH
RR 927-86-6 MSH
RR AF73293C2R MSH
RR C12HG588IF MSH
RXAUI 2067578 RXNORM
RXAUI 3092404 RXNORM
RXAUI 3095740 RXNORM
RXAUI 3095741 RXNORM
RXAUI 3104912 RXNORM
RXAUI 3104933 RXNORM
RXAUI 3155740 RXNORM
RXAUI 5433 RXNORM
RXAUI 6394934 RXNORM
RXAUI 6394988 RXNORM
RXCUI 194 RXNORM
SID EXPT00412 DRUGBANK
SPL_SET_ID 0012578b-66ff-49a8-8415-693c68ab9c16 MTHSPL
SPL_SET_ID 04f2642b-fd1c-4181-89c7-eace044a8984 MTHSPL
SPL_SET_ID 0735b8c0-fd9c-4154-9a08-8c2d2200ec93 MTHSPL
SPL_SET_ID 076587d3-46a0-48e5-9425-f5e1f5847ee3 MTHSPL
SPL_SET_ID 0b94f4c6-7907-4162-ab8f-15e881adcfa5 MTHSPL
SPL_SET_ID 10007c6a-1e22-4221-bde7-ff8e63ab9adc MTHSPL
SPL_SET_ID 11c56d03-d663-47b0-ac5a-f4ed3ba7f46b MTHSPL
SPL_SET_ID 160afc8d-b485-41ac-97ad-96f567ace387 MTHSPL
SPL_SET_ID 19aa6ca2-66e9-42e7-91e4-93220da84a08 MTHSPL
SPL_SET_ID 2801988f-18a8-491b-b7fd-132dedc3e4c6 MTHSPL
SPL_SET_ID 2bc74ff2-09fb-4f4a-af90-4d6ce0256945 MTHSPL
SPL_SET_ID 30bf403b-5408-4089-af74-f06a78ce6214 MTHSPL
SPL_SET_ID 33c0a5ad-3a7a-44c3-862d-288f4a7bc5c4 MTHSPL
SPL_SET_ID 350f76f7-a6de-48b9-a09a-847ba4041180 MTHSPL
SPL_SET_ID 389c57fd-b4cf-4997-a350-043c131cbfc4 MTHSPL
SPL_SET_ID 3ac392a3-7ef2-4bf8-97b4-30d32d66a088 MTHSPL
SPL_SET_ID 3af34476-26df-8ecd-2198-40b6ee5708b0 MTHSPL
SPL_SET_ID 4533d8c9-b35c-4753-bb72-ba4fffd0f1a9 MTHSPL
SPL_SET_ID 49f31fe2-bb1f-4596-b748-86ae0567c261 MTHSPL
SPL_SET_ID 4a8a6aaf-d676-469c-bd47-2f543332c25c MTHSPL
SPL_SET_ID 4b5af55d-98f9-477d-9815-5cb67e44bfbf MTHSPL
SPL_SET_ID 50988b6f-184c-81f9-4e65-739a91e88906 MTHSPL
SPL_SET_ID 576e3499-260b-4cc9-87c8-b54375719dd3 MTHSPL
SPL_SET_ID 57c8ec91-5103-4e6f-a678-efa4d55145ae MTHSPL
SPL_SET_ID 59a111c0-b728-4f33-8528-4cb09ecf5ae3 MTHSPL
SPL_SET_ID 5c8f36b2-aec3-442a-bc13-d454a0de252b MTHSPL
SPL_SET_ID 62fd8726-8be8-4d32-a11e-85c02ef368c8 MTHSPL
SPL_SET_ID 6e77a40c-6c9d-44ed-8a62-1b3a508a69dc MTHSPL
SPL_SET_ID 70251489-1511-485e-bb95-6eaac218c27b MTHSPL
SPL_SET_ID 73e43367-3513-d0e3-ddb8-e7b10f420ec5 MTHSPL
SPL_SET_ID 74bdd5ad-0f93-4f2e-87a1-960d68458314 MTHSPL
SPL_SET_ID 7665d5a4-06d5-4d78-b7a9-481512b8a5ef MTHSPL
SPL_SET_ID 787ebb96-e635-4d45-a2b0-414bf848d862 MTHSPL
SPL_SET_ID 7e35a2c2-e1be-de39-27ee-f462c3cbbc07 MTHSPL
SPL_SET_ID 82e64e99-daa7-4ffc-ac8f-c837c13f99c1 MTHSPL
SPL_SET_ID 89ef0203-5cb0-4c18-bfa4-e23e4f52d812 MTHSPL
SPL_SET_ID 91916d24-940c-4f6c-85ef-f1524f1db5c7 MTHSPL
SPL_SET_ID a6feaedd-9044-42d8-9bb7-63ee3d3094a1 MTHSPL
SPL_SET_ID b3abed0f-4d8c-42b5-8b28-f7bfb3fcb0eb MTHSPL
SPL_SET_ID b6637f00-3660-4fc5-acbd-4f1dfb02e80d MTHSPL
SPL_SET_ID b67c4ec1-20ee-4607-abdf-7989ad6c47e0 MTHSPL
SPL_SET_ID bd9698e8-1f5e-4881-8b58-beb6b632198e MTHSPL
SPL_SET_ID c98abc4d-8539-42e9-954a-5a850f28c9ed MTHSPL
SPL_SET_ID cf3a9cde-f74e-ebbb-1d6a-58c6a0bd0bd6 MTHSPL
SPL_SET_ID d0b9f2d6-bd1c-4e20-a0a4-3c85005f6e88 MTHSPL
SPL_SET_ID dd6b7ad0-0dca-40a0-9b38-5856f1893281 MTHSPL
SPL_SET_ID e64fa825-e087-4851-8f3a-d460dc8ebce3 MTHSPL
SPL_SET_ID e701ef07-9499-4b56-931f-f4eb3eedbe24 MTHSPL
SPL_SET_ID e8bfb8b0-43b4-4eb6-85c9-3abd8185a8c3 MTHSPL
SPL_SET_ID e96ed884-239a-4676-aa3c-a472d8e23a61 MTHSPL
SPL_SET_ID ec9fdbfe-9c4d-427c-9243-df155fa4e7d3 MTHSPL
SPL_SET_ID f13a92ec-bb94-4ebd-acaa-b9ad14d67cac MTHSPL
SPL_SET_ID f6792297-b480-48a9-a7c4-2f0c434a23b0 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU7ZM SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUGlR SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T000309 MSH
TERMUI T000310 MSH
TH FDA SRS (2014) MSH
TH NLM (1966) MSH
TH NLM (1995) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
UWT Anatomical Structure UWDA
VANDF_RECORD 50.416^2212^Active/Master NDFRT
VUID 4019594 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0001041

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