Concept Unique Identifier (CUI): C0043454

Semantic Type: Organic Chemical

Semantic Type: Hazardous or Poisonous Substance

MSH Definition: (S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione. One of a group of compounds known under the general designation of resorcylic acid lactones. Cis, trans, dextro and levo forms have been isolated from the fungus Gibberella zeae (formerly Fusarium graminearum). They have estrogenic activity, cause toxicity in livestock as feed contaminant, and have been used as anabolic or estrogen substitutes.

Synonyms & Abbreviations: (see Synonym Details)

1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-, (S-(E))-

F 2 Toxin

F A 02 TOXIN

F-2 Toxin

F2 Toxin

Toxin, F-2

Toxin, F2

Zearalenone (substance)

Zearalenone

External Source Codes:  (none)

Other Properties:

Name	Value	Source
ACTIVE	1	SNOMEDCT_US
AN	a mycotoxin & non-steroidal estrogen; do not confuse with zearalanone (index under ZEARALENONE /analogs)	MSH
AQL	AA AD AE AG AI AN BI BL CF CH CL CS EC GE HI IM IP ME PD PK PO RE SD ST TO TU UR	MSH
CASE_SIGNIFICANCE_ID	900000000000017005	SNOMEDCT_US
CTV3ID	XUK0e	SNOMEDCT_US
DC	1	MSH
DEFINITION_STATUS_ID	900000000000074008	SNOMEDCT_US
DX	19910101	MSH
EFFECTIVE_TIME	20020131	SNOMEDCT_US
HN	91(75); was see under RESORCINOLS 1975-90	MSH
MDA	19741111	MSH
MMR	20130708	MSH
MN	D02.455.426.559.389.657.852.900	MSH
MN	D02.540.950	MSH
MN	D23.946.587.989	MSH
PA	D004968	MSH
PM	91; was see under RESORCINOLS 1975-90	MSH
RN	5W827M159J	MSH
RR	17924-92-4 (Zearalenone)	MSH
SUBSET_MEMBER	900000000000497000~MAPTARGET~XUK0e	SNOMEDCT_US
TERMUI	T043833	MSH
TERMUI	T043834	MSH
TERMUI	T043835	MSH
TH	FDA SRS (2014)	MSH
TH	NLM (1975)	MSH
TH	UNK (19XX)	MSH
TYPE_ID	900000000000003001	SNOMEDCT_US
TYPE_ID	900000000000013009	SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0043454