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| Terms & Properties |
Concept Unique Identifier (CUI): C0035258
NCI Thesaurus Code: C84501 (see NCI Thesaurus info)
Semantic Type: Disease or Syndrome
NCIt Definition: A condition that occurs while resting or lying in bed; it is characterized by an irresistible urgency to move the legs to obtain relief from a strange and uncomfortable sensation in the legs.
MSH Definition: A disorder characterized by aching or burning sensations in the lower and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep.
NCI-GLOSS Definition: A condition in which a person has a strong urge to move his or her legs in order to stop uncomfortable sensations. These include burning, itching, creeping, tugging, crawling, or pain. These feelings usually happen when a person is lying or sitting down, and are worse at night. They can also occur in other parts of the body.
NICHD Definition: Uncomfortable or painful sensation associated with an irresistible urge to move the limbs, usually triggered by relaxation or lying down.
MEDLINEPLUS Definition:
Restless legs syndrome (RLS) causes a powerful urge to move your legs. Your legs become uncomfortable when you are lying down or sitting. Some people describe it as a creeping, crawling, tingling, or burning sensation. Moving makes your legs feel better, but not for long. RLS can make it hard to fall asleep and stay asleep.
In most cases, there is no known cause for RLS. In other cases, RLS is caused by a disease or condition, such as anemia or pregnancy. Some medicines can also cause temporary RLS. Caffeine, tobacco, and alcohol may make symptoms worse.
Lifestyle changes, such as regular sleep habits, relaxation techniques, and moderate exercise during the day can help. If those don't work, medicines may reduce the symptoms of RLS.
Most people with RLS also have a condition called periodic limb movement disorder (PLMD). PLMD is a condition in which a person's legs twitch or jerk uncontrollably, usually during sleep. PLMD and RLS can also affect the arms.
NIH: National Heart, Lung, and Blood Institute
FDA Definition: A condition that is characterized by an irresistible urgency to move the legs to obtain relief from a strange and uncomfortable sensation in the legs.
HPO Definition: A feeling of uneasiness and restlessness in the legs after going to bed (sometimes causing insomnia). [https://orcid.org/0000-0002-0736-9199]
CSP Definition: neurological disorder characterized by unpleasant sensations of the legs and an urge to move them for relief; usually occurs during or just prior to sleep, causing difficulty falling asleep or staying asleep.
Synonyms & Abbreviations: (see Synonym Details)
| Disease, Willis Ekbom |
| Disease, Willis-Ekbom |
| ekbom syndrome |
| LEGS RESTLESS |
| RESTLESS LEG SYNDROME |
| Restless legs (disorder) |
| Restless legs syndrome (RLS) |
| restless legs syndrome |
| RESTLESS LEGS |
| RLS |
| SYNDROME RESTLESS LEGS |
| Syndrome, Restless Leg |
| Syndrome, Willis Ekbom |
| Syndrome, Willis-Ekbom |
| Syndrome, Wittmaack Ekbom |
| Syndrome, Wittmaack-Ekbom |
| Willis Ekbom Disease |
| Willis Ekbom Syndrome |
| Willis-Ekbom disease |
| Willis-Ekbom Syndrome |
| Wittmaack Ekbom Syndrome |
| Wittmaack-Ekbom syndrome |
External Source Codes:
| NCI Thesaurus Code | C84501 (see NCI Thesaurus info) |
Other Properties:
| Name | Value | Source |
|---|---|---|
| ACTIVE | 1 | SNOMEDCT_US |
| AN | note entry terms containing "Ekbom": do not confuse with entry terms for DELUSIONAL PARASITOSIS which also contain "Ekbom" | MSH |
| AQL | BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI | MSH |
| CASE_SIGNIFICANCE_ID | 900000000000017005 | SNOMEDCT_US |
| CASE_SIGNIFICANCE_ID | 900000000000448009 | SNOMEDCT_US |
| Contributing_Source | FDA | NCI |
| Contributing_Source | mCode | NCI |
| Contributing_Source | MedDRA | NCI |
| Contributing_Source | NICHD | NCI |
| CTV3ID | F13z2 | SNOMEDCT_US |
| DATE_CREATED | 07/01/1999 | MEDLINEPLUS |
| DATE_CREATED | 2013-11-23T07:42:59Z | HPO |
| DC | 1 | MSH |
| DEFINITION_STATUS_ID | 900000000000074008 | SNOMEDCT_US |
| DID | 5006-0032 | CSP |
| DX | 19730101 | MSH |
| EFFECTIVE_TIME | 20020131 | SNOMEDCT_US |
| HN | 2000(1973) | MSH |
| HPO_COMMENT | Restless legs syndrome is a disorder characterized by aching or burning sensations in the legs that occur prior to sleep or may awaken the affected persons. Complying with an irresistible urge to move the affected limbs brings temporary relief. Sleep may become disrupted, resulting in excessive daytime hypersomnolence. | HPO |
| IPX | G25.8 | ICPC |
| MDA | 19990101 | MSH |
| MMR | 20130708 | MSH |
| MN | C10.803 | MSH |
| MN | C10.886.425.800.700 | MSH |
| MN | C10.886.659.634 | MSH |
| MN | F03.870.400.800.700 | MSH |
| MN | F03.870.664.634 | MSH |
| MP_OTHER_LANGUAGE_URL | Spanish https://medlineplus.gov/spanish/restlesslegs.html | MEDLINEPLUS |
| MP_PRIMARY_INSTITUTE_URL | National Institute of Neurological Disorders and Stroke http://www.ninds.nih.gov/ | MEDLINEPLUS |
| ORDER_NO | 06253 | ICD10CM |
| PM | 2000; see Restless Legs 1973-1999 | MSH |
| PRIMARY_PATH | 10058920$10040021$10029305$10029205$Restless legs syndrome$Sensory abnormalities NEC$Neurological disorders NEC$Nervous system disorders | MDR |
| PRIMARY_SOC | 10029205 | MDR |
| PT_IN_VERSION | 10.0 | MDR |
| PT_IN_VERSION | 10.1 | MDR |
| PT_IN_VERSION | 11.0 | MDR |
| PT_IN_VERSION | 11.1 | MDR |
| PT_IN_VERSION | 12.0 | MDR |
| PT_IN_VERSION | 12.1 | MDR |
| PT_IN_VERSION | 13.0 | MDR |
| PT_IN_VERSION | 13.1 | MDR |
| PT_IN_VERSION | 14.0 | MDR |
| PT_IN_VERSION | 14.1 | MDR |
| PT_IN_VERSION | 15.0 | MDR |
| PT_IN_VERSION | 15.1 | MDR |
| PT_IN_VERSION | 16.0 | MDR |
| PT_IN_VERSION | 16.1 | MDR |
| PT_IN_VERSION | 17.0 | MDR |
| PT_IN_VERSION | 17.1 | MDR |
| PT_IN_VERSION | 18.0 | MDR |
| PT_IN_VERSION | 18.1 | MDR |
| PT_IN_VERSION | 19.0 | MDR |
| PT_IN_VERSION | 19.1 | MDR |
| PT_IN_VERSION | 20.0 | MDR |
| PT_IN_VERSION | 20.1 | MDR |
| PT_IN_VERSION | 21.0 | MDR |
| PT_IN_VERSION | 21.1 | MDR |
| PT_IN_VERSION | 22.0 | MDR |
| PT_IN_VERSION | 22.1 | MDR |
| PT_IN_VERSION | 23.0 | MDR |
| PT_IN_VERSION | 23.1 | MDR |
| PT_IN_VERSION | 24.0 | MDR |
| PT_IN_VERSION | 24.1 | MDR |
| PT_IN_VERSION | 25.0 | MDR |
| PT_IN_VERSION | 25.1 | MDR |
| PT_IN_VERSION | 26.0 | MDR |
| PT_IN_VERSION | 8.0 | MDR |
| PT_IN_VERSION | 8.1 | MDR |
| PT_IN_VERSION | 9.0 | MDR |
| PT_IN_VERSION | 9.1 | MDR |
| SMQ_TERM_ADDVERSION | 23.0 | MDR |
| SMQ_TERM_CAT | A | MDR |
| SMQ_TERM_LEVEL | 5 | MDR |
| SMQ_TERM_LMVERSION | 23.0 | MDR |
| SMQ_TERM_SCOPE | 1 | MDR |
| SMQ_TERM_SCOPE | 2 | MDR |
| SMQ_TERM_STATUS | A | MDR |
| SMQ_TERM_WEIGHT | 0 | MDR |
| SOS | That creeping, crawling, tingling, or burning feeling in your legs when lying down or sitting may be restless leg syndrome (RLS). Learn what can help.https://medlineplus.gov/restlesslegs.html | MEDLINEPLUS |
| SUBSET_MEMBER | 900000000000497000~MAPTARGET~F13z2 | SNOMEDCT_US |
| SYN_QUALIFIER | layperson term | HPO |
| TERMUI | T036177 | MSH |
| TERMUI | T365808 | MSH |
| TERMUI | T829757 | MSH |
| TERMUI | T829758 | MSH |
| TERMUI | T829759 | MSH |
| TERMUI | T829760 | MSH |
| TERMUI | T829761 | MSH |
| TERMUI | T829762 | MSH |
| TERMUI | T830589 | MSH |
| TH | NLM (1973) | MSH |
| TH | NLM (2000) | MSH |
| TH | NLM (2014) | MSH |
| TYPE_ID | 900000000000003001 | SNOMEDCT_US |
| TYPE_ID | 900000000000013009 | SNOMEDCT_US |
Additional Concept Data: (none)
URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0035258
