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| Terms & Properties |
Note: The CUI C0025033 you searched for is obsolete.
Concept Unique Identifier (CUI): C0025033
NCI Thesaurus Code: C62056 (see NCI Thesaurus info)
Semantic Type: Hazardous or Poisonous Substance
Semantic Type: Pharmacologic Substance
Semantic Type: Organic Chemical
NCIt Definition: A synthetic agent related to sulphur mustard with antineoplastic and immunosuppressive properties. Nitrogen mustard (a member of a family of chemotherapy agents including cyclophosphamide and chlorambucil) is an irritant and carcinogenic agent metabolized to a highly reactive ethylene immonium derivative; the ethylene immonium derivative alkylates DNA and inhibits DNA replication. This agent also exhibits lympholytic properties. (NCI04)
MSH Definition: A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.
CDISC Definition: The nitrogen mustard vesicant HN-2.
CSP Definition: antineoplastic cytotoxic alkylating agent of the nitrogen mustard group.
Synonyms & Abbreviations: (see Synonym Details)
| 2,2'-dichloro-N-methyldiethylamine |
| bis(2-chloroethyl)methylamine |
| bis(β-chloroethyl)methylamine |
| chloramin |
| Chlorethazine |
| Chlormethine (substance) |
| Chlormethine-containing product |
| Chlormethine |
| Chlormethinum |
| chloromethine |
| Clormetina |
| Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl- |
| ethanamine,2-chloro-N-(2-chloroethyl)-N-methyl |
| HN 2 |
| HN2 |
| HN2 |
| HN>2< |
| Mechlorethamine-containing product |
| mechlorethamine |
| methylbis(2-chloroethyl)amine |
| Methylbis(beta-chloroethyl)amine |
| methylbis(β-chloroethyl)amine |
| Methylchlorethamine |
| Mustard |
| Mustine |
| N-methyl-bis(2-chloroethyl)amine |
| N-methyl-bis(β-chloroethyl)amine |
| NH-2 |
| NH2 |
| NITROGEN MUSTARD HN-2 |
| Nitrogen mustard |
| NM |
| Product containing chlormethine (medicinal product) |
| β,β'-dichlorodiethyl-N-methylamine |
External Source Codes:
| NCI Thesaurus Code | C62056 (see NCI Thesaurus info) |
| CAS Registry Number | 51-75-2 (see NLM ChemIDplus info) |
| FDA UNII Code | 50D9XSG0VR |
Other Properties:
| Name | Value | Source |
|---|---|---|
| ACTIVE | 1 | SNOMEDCT_US |
| AQL | AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR | MSH |
| CASE_SIGNIFICANCE_ID | 900000000000017005 | SNOMEDCT_US |
| CASE_SIGNIFICANCE_ID | 900000000000448009 | SNOMEDCT_US |
| CHEBI_ID | CHEBI:28925 | NCI |
| Chemical_Formula | C5H11Cl2N | NCI |
| Contributing_Source | CDISC | NCI |
| Contributing_Source | FDA | NCI |
| Contributing_Source | GDC | NCI |
| Contributing_Source | HemOnc | NCI |
| Contributing_Source | PCDC | NCI |
| CTV3ID | XUB7m | SNOMEDCT_US |
| CTV3ID | XUVzE | SNOMEDCT_US |
| DC | 1 | MSH |
| DEFINITION_STATUS_ID | 900000000000073002 | SNOMEDCT_US |
| DEFINITION_STATUS_ID | 900000000000074008 | SNOMEDCT_US |
| DID | 1371-8974 | CSP |
| DX | 19630101 | MSH |
| EFFECTIVE_TIME | 20020731 | SNOMEDCT_US |
| EFFECTIVE_TIME | 20180731 | SNOMEDCT_US |
| FDA_UNII_CODE | 50D9XSG0VR | DRUGBANK |
| HN | MECHLORETHAMINE OXIDE was heading 1963-79; NITROGEN MUSTARD N-OXIDE was NITROGEN MUSTARD N-OXIDE (NM) 1984-91 | MSH |
| MDA | 19990101 | MSH |
| MMR | 20160701 | MSH |
| MN | D02.455.526.728.650.529 | MSH |
| OL | use MECHLORETHAMINE to search MECHLORETHAMINE OXIDE 1966-79; use MECHLORETHAMINE (NM) to search NITROGEN MUSTARD N-OXIDE (NM) 1984-91 | MSH |
| PA | D000477 | MSH |
| PA | D002619 | MSH |
| PA | D007509 | MSH |
| PA | D018906 | MSH |
| PM | MECHLORETHAMINE OXIDE was heading 1963-79; NITROGEN MUSTARD N-OXIDE was indexed under NITROGEN MUSTARD COMPOUNDS 1984-91 | MSH |
| RN | 50D9XSG0VR | MSH |
| RR | 126-85-2 (N-oxide) | MSH |
| RR | 302-70-5 (N-oxide, HCl) | MSH |
| RR | 51-75-2 | MSH |
| RR | 55-86-7 (HCl) | MSH |
| RR | L0MR697HHI | MSH |
| RXAUI | 10824948 | RXNORM |
| RXAUI | 10824949 | RXNORM |
| RXAUI | 10824950 | RXNORM |
| RXAUI | 10824951 | RXNORM |
| RXAUI | 10824952 | RXNORM |
| RXAUI | 10824953 | RXNORM |
| RXAUI | 10824954 | RXNORM |
| RXAUI | 12251035 | RXNORM |
| RXAUI | 2072190 | RXNORM |
| RXAUI | 216751 | RXNORM |
| RXAUI | 216791 | RXNORM |
| RXAUI | 5529982 | RXNORM |
| RXAUI | 7870754 | RXNORM |
| RXAUI | 7902060 | RXNORM |
| RXAUI | 7975987 | RXNORM |
| RXAUI | 8059960 | RXNORM |
| RXAUI | 8102387 | RXNORM |
| RXAUI | 8127929 | RXNORM |
| RXAUI | 8267828 | RXNORM |
| RXAUI | 8386315 | RXNORM |
| RXAUI | 8409689 | RXNORM |
| RXAUI | 8462321 | RXNORM |
| RXAUI | 8555023 | RXNORM |
| RXAUI | 8601000 | RXNORM |
| RXAUI | 8683372 | RXNORM |
| RXAUI | 9270383 | RXNORM |
| RXCUI | 6674 | RXNORM |
| SID | APRD00249 | DRUGBANK |
| SPL_SET_ID | 6a52e4c2-6a9f-4ebb-bc77-046b4f8bcd57 | MTHSPL |
| SUBSET_MEMBER | 900000000000497000~MAPTARGET~XUB7m | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000497000~MAPTARGET~XUVzE | SNOMEDCT_US |
| TERMUI | T025151 | MSH |
| TERMUI | T025152 | MSH |
| TERMUI | T025155 | MSH |
| TERMUI | T025156 | MSH |
| TERMUI | T025157 | MSH |
| TERMUI | T025159 | MSH |
| TERMUI | T025160 | MSH |
| TH | BAN (19XX) | MSH |
| TH | FDA SRS (2015) | MSH |
| TH | INN (19XX) | MSH |
| TH | NLM (1966) | MSH |
| TH | NLM (1992) | MSH |
| TH | UNK (19XX) | MSH |
| TH | USAN (19XX) | MSH |
| TYPE_ID | 900000000000003001 | SNOMEDCT_US |
| TYPE_ID | 900000000000013009 | SNOMEDCT_US |
Additional Concept Data: (none)
URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0025033
